IL75448A - Insulin formulations,processes for their preparation and their use - Google Patents
Insulin formulations,processes for their preparation and their useInfo
- Publication number
- IL75448A IL75448A IL75448A IL7544885A IL75448A IL 75448 A IL75448 A IL 75448A IL 75448 A IL75448 A IL 75448A IL 7544885 A IL7544885 A IL 7544885A IL 75448 A IL75448 A IL 75448A
- Authority
- IL
- Israel
- Prior art keywords
- plunger pipe
- plate
- damper
- sealing plate
- pipe
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
- 102000004877 Insulin Human genes 0.000 title 1
- 108090001061 Insulin Proteins 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 229940125396 insulin Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 238000007789 sealing Methods 0.000 abstract 3
- 238000009434 installation Methods 0.000 abstract 2
- 229920000297 Rayon Polymers 0.000 abstract 1
- 238000013016 damping Methods 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 230000010349 pulsation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Luminescent Compositions (AREA)
- Steroid Compounds (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Prostheses (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3421615 | 1984-06-09 | ||
| DE3421613 | 1984-06-09 | ||
| DE19843443877 DE3443877A1 (de) | 1984-06-09 | 1984-12-01 | Insulinzubereitungen, verfahren zu deren herstellung und deren verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL75448A0 IL75448A0 (en) | 1985-10-31 |
| IL75448A true IL75448A (en) | 1989-07-31 |
Family
ID=27192050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL75448A IL75448A (en) | 1984-06-09 | 1985-06-07 | Insulin formulations,processes for their preparation and their use |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0166971B1 (fi) |
| AT (1) | ATE50502T1 (fi) |
| AU (1) | AU575951B2 (fi) |
| CA (1) | CA1258427A (fi) |
| DE (1) | DE3576120D1 (fi) |
| DK (1) | DK162255C (fi) |
| ES (1) | ES8605679A1 (fi) |
| FI (1) | FI80596C (fi) |
| GR (1) | GR851393B (fi) |
| HU (1) | HU200102B (fi) |
| IE (1) | IE57998B1 (fi) |
| IL (1) | IL75448A (fi) |
| NO (1) | NO164277C (fi) |
| NZ (1) | NZ212338A (fi) |
| PH (1) | PH24118A (fi) |
| PT (1) | PT80620B (fi) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO179479C (no) * | 1988-03-11 | 1996-10-16 | Teikoku Seiyaku Kk | Fremgangsmåte for fremstilling av et intravaginalt farmasöytisk preparat |
| DE10114178A1 (de) | 2001-03-23 | 2002-10-10 | Aventis Pharma Gmbh | Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität |
| DE10227232A1 (de) * | 2002-06-18 | 2004-01-15 | Aventis Pharma Deutschland Gmbh | Saure Insulinzubereitungen mit verbesserter Stabilität |
| LT3228320T (lt) | 2008-10-17 | 2020-03-10 | Sanofi-Aventis Deutschland Gmbh | Insulino ir glp-1 agonisto derinys |
| PE20121362A1 (es) | 2009-11-13 | 2012-10-17 | Sanofi Aventis Deutschland | Composicion farmaceutica que comprende despro36exendina-4(1-39)-lys6-nh2, insulina gly(a21)-arg(b31)-arg(b32) y metionina |
| KR101772372B1 (ko) | 2009-11-13 | 2017-08-29 | 사노피-아벤티스 도이칠란트 게엠베하 | Ｇｌｐ-1 효능제 및 메티오닌을 포함하는 약제학적 조성물 |
| EP2611458B1 (en) | 2010-08-30 | 2016-09-21 | Sanofi-Aventis Deutschland GmbH | Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2 |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| MX369511B (es) | 2013-04-03 | 2019-11-11 | Sanofi Sa | Tratamiento de la diabetes mellitus mediante formulaciones de insulinas de acción prolongada. |
| HRP20230470T1 (hr) | 2014-12-12 | 2023-07-21 | Sanofi-Aventis Deutschland Gmbh | Formulacija fiksnog omjera inzulin glargin/liksisenatid |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第２型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第２型糖尿病病患之治療 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2474729A (en) * | 1945-01-03 | 1949-06-28 | Rhone Poulenc Sa | Insulin preparations |
| US2574889A (en) * | 1947-10-06 | 1951-11-13 | Leo Ab | Methylated gelatin-insulin preparation |
| SU1011126A1 (ru) * | 1981-07-14 | 1983-04-15 | Всесоюзный научно-исследовательский и испытательный институт медицинской техники | Средство дл лечени сахарного диабета |
| ZW17382A1 (en) * | 1981-08-27 | 1982-11-17 | Lilly Co Eli | Human proinsulin pharmaceutical formulations |
| FI78616C (fi) * | 1982-02-05 | 1989-09-11 | Novo Industri As | Foerfarande foer framstaellning av en foer infusionsaendamaol avsedd stabiliserad insulinloesning, som har en foerhoejd zinkhalt. |
| WO1985005036A1 (en) * | 1984-04-30 | 1985-11-21 | The Trustees Of Columbia University In The City Of | Topical treatment of diabetes with insulin and penetrant enhancer applied to the skin and covered by a patch |
-
1985
- 1985-05-30 DE DE8585106669T patent/DE3576120D1/de not_active Expired - Lifetime
- 1985-05-30 AT AT85106669T patent/ATE50502T1/de not_active IP Right Cessation
- 1985-05-30 EP EP85106669A patent/EP0166971B1/de not_active Expired - Lifetime
- 1985-06-04 HU HU852203A patent/HU200102B/hu unknown
- 1985-06-06 DK DK254585A patent/DK162255C/da not_active IP Right Cessation
- 1985-06-06 FI FI852273A patent/FI80596C/fi not_active IP Right Cessation
- 1985-06-07 NO NO852314A patent/NO164277C/no unknown
- 1985-06-07 GR GR851393A patent/GR851393B/el unknown
- 1985-06-07 IL IL75448A patent/IL75448A/xx not_active IP Right Cessation
- 1985-06-07 NZ NZ212338A patent/NZ212338A/xx unknown
- 1985-06-07 PH PH32375A patent/PH24118A/en unknown
- 1985-06-07 AU AU43424/85A patent/AU575951B2/en not_active Expired
- 1985-06-07 CA CA000483496A patent/CA1258427A/en not_active Expired
- 1985-06-07 ES ES543972A patent/ES8605679A1/es not_active Expired
- 1985-06-07 IE IE1431/85A patent/IE57998B1/en not_active IP Right Cessation
- 1985-06-07 PT PT80620A patent/PT80620B/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE57998B1 (en) | 1993-06-02 |
| ES543972A0 (es) | 1986-01-16 |
| HU200102B (en) | 1990-04-28 |
| FI80596C (fi) | 1990-07-10 |
| DE3576120D1 (de) | 1990-04-05 |
| DK254585A (da) | 1985-12-10 |
| DK254585D0 (da) | 1985-06-06 |
| EP0166971A1 (de) | 1986-01-08 |
| FI852273A0 (fi) | 1985-06-06 |
| FI80596B (fi) | 1990-03-30 |
| ATE50502T1 (de) | 1990-03-15 |
| EP0166971B1 (de) | 1990-02-28 |
| HUT37893A (en) | 1986-03-28 |
| CA1258427A (en) | 1989-08-15 |
| DK162255C (da) | 1992-03-16 |
| PT80620A (de) | 1985-07-01 |
| NO164277C (no) | 1990-09-19 |
| IL75448A0 (en) | 1985-10-31 |
| DK162255B (da) | 1991-10-07 |
| NO164277B (no) | 1990-06-11 |
| ES8605679A1 (es) | 1986-01-16 |
| AU575951B2 (en) | 1988-08-11 |
| FI852273L (fi) | 1985-12-10 |
| NO852314L (no) | 1985-12-10 |
| GR851393B (en) | 1985-11-25 |
| IE851431L (en) | 1985-12-09 |
| AU4342485A (en) | 1985-12-12 |
| PT80620B (pt) | 1987-10-20 |
| PH24118A (en) | 1990-03-05 |
| NZ212338A (en) | 1989-02-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |