IL75361A - Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold,silver or copper complexes - Google Patents

Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold,silver or copper complexes

Info

Publication number
IL75361A
IL75361A IL75361A IL7536185A IL75361A IL 75361 A IL75361 A IL 75361A IL 75361 A IL75361 A IL 75361A IL 7536185 A IL7536185 A IL 7536185A IL 75361 A IL75361 A IL 75361A
Authority
IL
Israel
Prior art keywords
gold
silver
hydrocarbon
pharmaceutical compositions
cell growth
Prior art date
Application number
IL75361A
Other languages
English (en)
Other versions
IL75361A0 (en
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of IL75361A0 publication Critical patent/IL75361A0/xx
Publication of IL75361A publication Critical patent/IL75361A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/50Organo-phosphines
    • C07F9/5045Complexes or chelates of phosphines with metallic compounds or metals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL75361A 1984-06-04 1985-05-31 Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold,silver or copper complexes IL75361A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61662184A 1984-06-04 1984-06-04
US71890485A 1985-04-02 1985-04-02

Publications (2)

Publication Number Publication Date
IL75361A0 IL75361A0 (en) 1985-09-29
IL75361A true IL75361A (en) 1989-10-31

Family

ID=27087815

Family Applications (1)

Application Number Title Priority Date Filing Date
IL75361A IL75361A (en) 1984-06-04 1985-05-31 Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold,silver or copper complexes

Country Status (9)

Country Link
EP (1) EP0164970B1 (da)
AU (1) AU572665B2 (da)
CA (1) CA1244764A (da)
DE (1) DE3569535D1 (da)
DK (1) DK252885A (da)
HU (1) HU196815B (da)
IL (1) IL75361A (da)
NZ (1) NZ212295A (da)
PH (1) PH21350A (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1238854A (en) * 1984-02-01 1988-07-05 David T. Hill ANTITUMOR PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING TUMORS EMPLOYING ¬.alpha.,W- BIS(DISUBSTITUTEDPHOSPHINO)HYDROCARBON| DIGOLD (I) DIGOLD (III), DISILVER (I) AND DICOPPER (I) DERIVATIVES
US5037812A (en) * 1985-04-02 1991-08-06 Smithkline Beckman Corporation Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes
DK166686A (da) * 1985-04-16 1986-10-17 Smithkline Beckman Corp Phosphinforbindelser, fremgangsmaade til fremstilling heraf samt farmaceutiske midler indeholdende disse forbindelser
US4716230A (en) * 1985-04-16 1987-12-29 Smithkline Beckman Corporation Certain bis(di-2 or 4-pyridyl-phosphino) alkanes #10 having anti-tumor properties
US4902675A (en) * 1985-05-16 1990-02-20 Smithkline Beckman Corporation "2-pyridyl and 4-pyridyl phosphine gold (I) anti tumor complexes"
EP0202854A3 (en) * 1985-05-20 1988-01-13 Smithkline Beecham Corporation Phosphine gold compounds
US4675427A (en) * 1985-05-20 1987-06-23 Smith Kline Beckman Corporation Tetraphosphine-coordinated gold(I) complexes
US4698422A (en) * 1985-05-20 1987-10-06 Smithkline Beckman Corporation Triphos and tetraphos gold compounds and ligands
NL8502929A (nl) * 1985-10-25 1987-05-18 Tno Groep viii-overgangsmetaal-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijke groep viii-overgangsmetaal-complex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.
US4758589A (en) * 1985-12-23 1988-07-19 Smithkline Beckman Corporation Tetraphosphine-coordinated gold(I) complexes
US4764509A (en) * 1986-02-21 1988-08-16 Smithkline Beckman Corporation Pharmaceutical compositions containing di-gold phosphine
US4885376A (en) * 1987-10-13 1989-12-05 Iowa State University Research Foundation, Inc. New types of organometallic reagents and catalysts for asymmetric synthesis
JPH10509957A (ja) * 1994-12-09 1998-09-29 グリフィス ユニヴァーシティ 抗癌剤
JP5015451B2 (ja) * 2005-04-18 2012-08-29 日本化学工業株式会社 ホスフィン遷移金属錯体、その製造方法およびそれを含有する抗癌剤
CN102101874B (zh) * 2011-01-24 2013-06-12 安徽大学 新型含二茂铁吡唑基的铜、银配合物及用途
WO2017049529A1 (en) 2015-09-24 2017-03-30 Innolife Co., Ltd. A pharmaceutical composition comprising a copper chelating tetramine and the use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3661959A (en) * 1970-07-30 1972-05-09 Du Pont Method of making organogold chloride complexes
FR2422676A1 (fr) * 1977-07-18 1979-11-09 Hoffmann La Roche Complexes catalytiques de phosphorines metalliques
CA1238854A (en) * 1984-02-01 1988-07-05 David T. Hill ANTITUMOR PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING TUMORS EMPLOYING ¬.alpha.,W- BIS(DISUBSTITUTEDPHOSPHINO)HYDROCARBON| DIGOLD (I) DIGOLD (III), DISILVER (I) AND DICOPPER (I) DERIVATIVES

Also Published As

Publication number Publication date
EP0164970A3 (en) 1986-11-05
HU196815B (en) 1989-01-30
EP0164970A2 (en) 1985-12-18
HUT40446A (en) 1986-12-28
CA1244764A (en) 1988-11-15
DK252885A (da) 1985-12-05
DE3569535D1 (en) 1989-05-24
PH21350A (en) 1987-10-13
EP0164970B1 (en) 1989-04-19
IL75361A0 (en) 1985-09-29
DK252885D0 (da) 1985-06-04
NZ212295A (en) 1988-03-30
AU572665B2 (en) 1988-05-12
AU4326785A (en) 1985-12-12

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