DE3569535D1 - Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes - Google Patents
Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexesInfo
- Publication number
- DE3569535D1 DE3569535D1 DE8585303851T DE3569535T DE3569535D1 DE 3569535 D1 DE3569535 D1 DE 3569535D1 DE 8585303851 T DE8585303851 T DE 8585303851T DE 3569535 T DE3569535 T DE 3569535T DE 3569535 D1 DE3569535 D1 DE 3569535D1
- Authority
- DE
- Germany
- Prior art keywords
- gold
- silver
- hydrocarbon
- pharmaceutical compositions
- cell growth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001879 copper Chemical class 0.000 title 1
- 229910052737 gold Inorganic materials 0.000 title 1
- 239000010931 gold Substances 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229910052709 silver Inorganic materials 0.000 title 1
- 239000004332 silver Substances 0.000 title 1
- 230000004565 tumor cell growth Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5045—Complexes or chelates of phosphines with metallic compounds or metals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61662184A | 1984-06-04 | 1984-06-04 | |
| US71890485A | 1985-04-02 | 1985-04-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3569535D1 true DE3569535D1 (en) | 1989-05-24 |
Family
ID=27087815
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8585303851T Expired DE3569535D1 (en) | 1984-06-04 | 1985-05-31 | Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0164970B1 (de) |
| AU (1) | AU572665B2 (de) |
| CA (1) | CA1244764A (de) |
| DE (1) | DE3569535D1 (de) |
| DK (1) | DK252885A (de) |
| HU (1) | HU196815B (de) |
| IL (1) | IL75361A (de) |
| NZ (1) | NZ212295A (de) |
| PH (1) | PH21350A (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1238854A (en) * | 1984-02-01 | 1988-07-05 | David T. Hill | ANTITUMOR PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING TUMORS EMPLOYING ¬.alpha.,W- BIS(DISUBSTITUTEDPHOSPHINO)HYDROCARBON| DIGOLD (I) DIGOLD (III), DISILVER (I) AND DICOPPER (I) DERIVATIVES |
| US5037812A (en) * | 1985-04-02 | 1991-08-06 | Smithkline Beckman Corporation | Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes |
| US4716230A (en) * | 1985-04-16 | 1987-12-29 | Smithkline Beckman Corporation | Certain bis(di-2 or 4-pyridyl-phosphino) alkanes #10 having anti-tumor properties |
| DK166686A (da) * | 1985-04-16 | 1986-10-17 | Smithkline Beckman Corp | Phosphinforbindelser, fremgangsmaade til fremstilling heraf samt farmaceutiske midler indeholdende disse forbindelser |
| US4902675A (en) * | 1985-05-16 | 1990-02-20 | Smithkline Beckman Corporation | "2-pyridyl and 4-pyridyl phosphine gold (I) anti tumor complexes" |
| US4698422A (en) * | 1985-05-20 | 1987-10-06 | Smithkline Beckman Corporation | Triphos and tetraphos gold compounds and ligands |
| US4675427A (en) * | 1985-05-20 | 1987-06-23 | Smith Kline Beckman Corporation | Tetraphosphine-coordinated gold(I) complexes |
| EP0202854A3 (de) * | 1985-05-20 | 1988-01-13 | Smithkline Beecham Corporation | Phosphin-Gold-Verbindungen |
| NL8502929A (nl) * | 1985-10-25 | 1987-05-18 | Tno | Groep viii-overgangsmetaal-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijke groep viii-overgangsmetaal-complex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel. |
| US4758589A (en) * | 1985-12-23 | 1988-07-19 | Smithkline Beckman Corporation | Tetraphosphine-coordinated gold(I) complexes |
| US4764509A (en) * | 1986-02-21 | 1988-08-16 | Smithkline Beckman Corporation | Pharmaceutical compositions containing di-gold phosphine |
| US4885376A (en) * | 1987-10-13 | 1989-12-05 | Iowa State University Research Foundation, Inc. | New types of organometallic reagents and catalysts for asymmetric synthesis |
| JPH10509957A (ja) * | 1994-12-09 | 1998-09-29 | グリフィス ユニヴァーシティ | 抗癌剤 |
| JP5015451B2 (ja) | 2005-04-18 | 2012-08-29 | 日本化学工業株式会社 | ホスフィン遷移金属錯体、その製造方法およびそれを含有する抗癌剤 |
| CN102101874B (zh) * | 2011-01-24 | 2013-06-12 | 安徽大学 | 新型含二茂铁吡唑基的铜、银配合物及用途 |
| WO2017049529A1 (en) | 2015-09-24 | 2017-03-30 | Innolife Co., Ltd. | A pharmaceutical composition comprising a copper chelating tetramine and the use thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3661959A (en) * | 1970-07-30 | 1972-05-09 | Du Pont | Method of making organogold chloride complexes |
| FR2422676A1 (fr) * | 1977-07-18 | 1979-11-09 | Hoffmann La Roche | Complexes catalytiques de phosphorines metalliques |
| CA1238854A (en) * | 1984-02-01 | 1988-07-05 | David T. Hill | ANTITUMOR PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING TUMORS EMPLOYING ¬.alpha.,W- BIS(DISUBSTITUTEDPHOSPHINO)HYDROCARBON| DIGOLD (I) DIGOLD (III), DISILVER (I) AND DICOPPER (I) DERIVATIVES |
-
1985
- 1985-05-29 PH PH32332A patent/PH21350A/en unknown
- 1985-05-29 CA CA000482640A patent/CA1244764A/en not_active Expired
- 1985-05-31 IL IL75361A patent/IL75361A/xx unknown
- 1985-05-31 DE DE8585303851T patent/DE3569535D1/de not_active Expired
- 1985-05-31 EP EP85303851A patent/EP0164970B1/de not_active Expired
- 1985-06-03 HU HU852152A patent/HU196815B/hu not_active IP Right Cessation
- 1985-06-04 AU AU43267/85A patent/AU572665B2/en not_active Ceased
- 1985-06-04 NZ NZ212295A patent/NZ212295A/en unknown
- 1985-06-04 DK DK252885A patent/DK252885A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK252885A (da) | 1985-12-05 |
| DK252885D0 (da) | 1985-06-04 |
| EP0164970A3 (en) | 1986-11-05 |
| CA1244764A (en) | 1988-11-15 |
| IL75361A (en) | 1989-10-31 |
| NZ212295A (en) | 1988-03-30 |
| EP0164970B1 (de) | 1989-04-19 |
| HU196815B (en) | 1989-01-30 |
| EP0164970A2 (de) | 1985-12-18 |
| PH21350A (en) | 1987-10-13 |
| IL75361A0 (en) | 1985-09-29 |
| AU4326785A (en) | 1985-12-12 |
| HUT40446A (en) | 1986-12-28 |
| AU572665B2 (en) | 1988-05-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB2160867B (en) | Platinum (iv) complexes | |
| DE3569535D1 (en) | Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes | |
| DE3260164D1 (en) | Novel platinum complexes | |
| AU559983B2 (en) | Platinum complexes, treatment of cancer | |
| GB2157563B (en) | Pharmaceutical compositions containing iron complexes | |
| IL64847A0 (en) | Hexapyranose compounds,their manufacture and pharmaceutical compositions containing them | |
| GB8512217D0 (en) | Polyarylenesulfide complexes | |
| IL65951A (en) | Alpha-hydroxy-2-azolylmethylphenylacetic acid derivatives,their preparation and fungicidal compositions containing them | |
| IL61971A (en) | Polyether compounds x-14868,their manufacture and pharmaceutical compositions containing them | |
| ZA852166B (en) | Iodophor compositions | |
| JPS57113505A (en) | Conductive composition | |
| ZA859582B (en) | Platinum complexes | |
| IL61080A0 (en) | Pharmaceutical composition containing zinc ions | |
| ZA854206B (en) | Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold,silver or copper complexes | |
| IL62517A (en) | Pharmaceutical compositions comprising cisplatin | |
| AU4311085A (en) | Copper salt and ligand containing composition | |
| EP0074411A4 (de) | Ascorbinsäureabkömmlinge. | |
| JPS56128503A (en) | Thick silver composition | |
| JPS57158905A (en) | Conductive composition | |
| ZA856889B (en) | Platinum complexes | |
| GB2089659B (en) | Compositions containing silver salts | |
| AU549637B2 (en) | N,n-diphenyl-3,5-dioxo-pyrazolidine copper complexes | |
| PH22215A (en) | Platinum ii complexes of 1,1-cyclobutane-dicarboxylate | |
| JPS5782375A (en) | Medicinal composition containing 2,4-diamino-benzylpyrimidine salt | |
| IL78836A0 (en) | Phenoxyalkyltriazoles,their preparation and fungicidal compositions containing them |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |