IL74066A - 6,6-ethylene-15,16-methylene-3-oxo-17alpha-pregn-4-ene-21,17-carbolactones,processes for the production thereof and pharmaceutical preparations containing them - Google Patents

6,6-ethylene-15,16-methylene-3-oxo-17alpha-pregn-4-ene-21,17-carbolactones,processes for the production thereof and pharmaceutical preparations containing them

Info

Publication number
IL74066A
IL74066A IL74066A IL7406685A IL74066A IL 74066 A IL74066 A IL 74066A IL 74066 A IL74066 A IL 74066A IL 7406685 A IL7406685 A IL 7406685A IL 74066 A IL74066 A IL 74066A
Authority
IL
Israel
Prior art keywords
carbolactones
pregn
ene
oxo
methylene
Prior art date
Application number
IL74066A
Other languages
English (en)
Other versions
IL74066A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL74066A0 publication Critical patent/IL74066A0/xx
Publication of IL74066A publication Critical patent/IL74066A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL74066A 1984-01-20 1985-01-16 6,6-ethylene-15,16-methylene-3-oxo-17alpha-pregn-4-ene-21,17-carbolactones,processes for the production thereof and pharmaceutical preparations containing them IL74066A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843402329 DE3402329A1 (de) 1984-01-20 1984-01-20 6,6-ethylen-15,16-methylen-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate

Publications (2)

Publication Number Publication Date
IL74066A0 IL74066A0 (en) 1985-04-30
IL74066A true IL74066A (en) 1988-07-31

Family

ID=6225757

Family Applications (1)

Application Number Title Priority Date Filing Date
IL74066A IL74066A (en) 1984-01-20 1985-01-16 6,6-ethylene-15,16-methylene-3-oxo-17alpha-pregn-4-ene-21,17-carbolactones,processes for the production thereof and pharmaceutical preparations containing them

Country Status (18)

Country Link
US (1) US4584288A (ja)
EP (1) EP0150157B1 (ja)
JP (1) JPS60161997A (ja)
AT (1) ATE35995T1 (ja)
AU (1) AU568715B2 (ja)
CA (1) CA1267888A (ja)
DD (1) DD232281A5 (ja)
DE (2) DE3402329A1 (ja)
DK (1) DK164326C (ja)
ES (1) ES8605535A1 (ja)
FI (1) FI82252C (ja)
GR (1) GR850138B (ja)
HU (1) HU192291B (ja)
IE (1) IE57837B1 (ja)
IL (1) IL74066A (ja)
NO (1) NO164546C (ja)
PT (1) PT79839B (ja)
ZA (1) ZA85441B (ja)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3615376A1 (de) * 1986-05-07 1987-11-12 Schering Ag 2,2;6,6-diethylen-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
DE3916112A1 (de) * 1989-05-16 1990-11-22 Schering Ag Dihydrospirorenon als antiandrogen
US8445469B2 (en) * 2004-12-30 2013-05-21 Bayer Intellectual Property Gmbh 18-methyl-19-nor-17-pregn-4-ene-21,17-carbolactones, as well as pharmaceutical preparations that contain the latter
DE102004063864A1 (de) * 2004-12-30 2006-07-13 Schering Ag 18-Methyl-19-nor-17-pregn-4-en21,17-carbolactone, sowie diese enthaltende pharmazeutische Präparate
DE102006030416A1 (de) * 2006-06-29 2008-01-03 Bayer Schering Pharma Ag 18-Methyl-19-nor-androst-4-en-17,17-spiroether (18-Methyl-19-nor-20-spirox-4-en-3-one) sowie diese enthaltende pharmazeutische Präparate
DE102007027637A1 (de) 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17ß-Cyano-19-nor-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007027636A1 (de) * 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17ß-Cyano-18a-homo-19-nor-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007027635A1 (de) 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17ß-Cyano-19-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063500A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 17-(1'-Propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063503A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-19-nor-21-carbonsäure-Steroid y-Lacton-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063499A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft Steroid-17,17-Lactol-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063495A1 (de) * 2007-12-29 2009-09-17 Bayer Schering Pharma Aktiengesellschaft 19-Nor-Steroidderivate mit einer 15α,16α-Methylengruppe und einem gesättigten 17,17-Spirolactonring, deren Verwendung sowie diese Derivate enthaltende Arzneimittel
DE102007063498A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 15,16-Methylen-steroid-17,17-Lactol-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063496A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 15,16-Methylen-17-(1'-propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063501A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 15, 16-Methylen-17-hydroxy-19-nor-21-carbonsäure-Steroid y-Lacton-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
WO2009111574A2 (en) * 2008-03-05 2009-09-11 Evestra, Inc. BISMETHYLENE-17α CARBOLACTONES AND RELATED USES
EP2367808A4 (en) * 2008-11-25 2012-05-09 Evestra Inc g-LACTONES OF 3- (6,6-ETHYLENE-17β-HYDROXY-3-OXO-17α-PREGEN-4-EENE-17α-YL) PROGESTATIVE PROPIONIC ACID

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3422097A (en) * 1965-08-27 1969-01-14 Smithkline Corp 6,6-ethylene spirolactones
DE2652761C2 (de) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE3227598A1 (de) * 1982-07-22 1984-01-26 Schering AG, 1000 Berlin und 4709 Bergkamen 7(alpha)-acylthio-15.16-methylen-3-oxo-17(alpha)-pregna-1.4-dien-21,17-carbolactone, verfahren zu ihrer herstellung und verwendung als arzneimittel
DE3234972A1 (de) * 1982-09-17 1984-03-22 Schering AG, 1000 Berlin und 4709 Bergkamen 7(alpha)-alkyl-17(alpha)-pregn-4-en-21.17-carbolactone und -21-carbonsaeuresalze sowie verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Also Published As

Publication number Publication date
IL74066A0 (en) 1985-04-30
FI850151A0 (fi) 1985-01-14
DD232281A5 (de) 1986-01-22
DE3402329A1 (de) 1985-08-01
AU3791285A (en) 1985-08-01
GR850138B (ja) 1985-05-13
EP0150157A2 (de) 1985-07-31
ZA85441B (en) 1985-09-25
IE57837B1 (en) 1993-04-21
ATE35995T1 (de) 1988-08-15
US4584288A (en) 1986-04-22
NO164546B (no) 1990-07-09
JPS60161997A (ja) 1985-08-23
PT79839A (en) 1985-02-01
EP0150157A3 (en) 1985-08-28
HU192291B (en) 1987-05-28
FI850151L (fi) 1985-07-21
DK164326C (da) 1992-11-02
JPH0564638B2 (ja) 1993-09-16
HUT37631A (en) 1986-01-23
DE3563970D1 (en) 1988-09-01
FI82252B (fi) 1990-10-31
NO164546C (no) 1990-10-17
IE850112L (en) 1985-07-20
DK15385A (da) 1985-07-21
ES539683A0 (es) 1986-04-01
PT79839B (en) 1986-10-23
FI82252C (fi) 1991-02-11
DK164326B (da) 1992-06-09
NO850224L (no) 1985-07-22
CA1267888A (en) 1990-04-17
AU568715B2 (en) 1988-01-07
EP0150157B1 (de) 1988-07-27
ES8605535A1 (es) 1986-04-01
DK15385D0 (da) 1985-01-11

Similar Documents

Publication Publication Date Title
GR82548B (en) Iib - aryl - estradien, preparation thereof, an pharmaceutical preparations containing said compound
ZA85441B (en) 6,6-ethylene-15,16-methylene-3-oxo-17alpha-pregn-4-ene-21,17-carbolactones,processes for the production thereof,and pharmaceutical preparations containing them
EP0326196A3 (en) Aqueous pharmaceutical preparation
IL77430A (en) 3-alkyl-and 3,8-dialkyl-6-thioxanthine and pharmaceutical compositions containing them
IL83302A (en) 14,17beta-ethano-14 beta-estratrienes and estratetraenes,processes for their production and pharmaceutical preparations containing them
ES2001665A6 (es) Procedimiento para preparar tripeptidos alquilados en n
ES8704487A1 (es) Procedimiento para preparar derivados de 3,4-diazol
ES8500280A1 (es) Procedimiento para la produccion de un alcaloide peptidico 5's-(2r-butilo) del cornezuelo de centeno.
DE3663664D1 (en) Compounds having antiplatelet aggregation activity, a process for the preparation thereof and pharmaceutical compositions containing them
AU7351787A (en) 2,2,6,6-diethylene-3-oxo-17-alpha-pregn-4-en-21,17- carbolactones
ES8606868A1 (es) Procedimiento para la obtencion de derivados de la 1,4-dihi-dro-piridina
SU1121940A1 (ru) Этиловый эфир [3-метил-5- 2′ -оксифенил)-1,2,4-триазолил-1] уксусной кислоты, обладающий психостимулирующим действием
IE861924L (en) "new derivatives of diphenoxyethylamine, a process for their¹production and the pharmaceutical compositions containing¹the same"

Legal Events

Date Code Title Description
KB Patent renewed
RH1 Patent not in force