IL73884A - Aspidosperimidine-3-carboxylic acid derivatives and their use in preparing vincristine - Google Patents
Aspidosperimidine-3-carboxylic acid derivatives and their use in preparing vincristineInfo
- Publication number
- IL73884A IL73884A IL73884A IL7388484A IL73884A IL 73884 A IL73884 A IL 73884A IL 73884 A IL73884 A IL 73884A IL 7388484 A IL7388484 A IL 7388484A IL 73884 A IL73884 A IL 73884A
- Authority
- IL
- Israel
- Prior art keywords
- aspidosperimidine
- carboxylic acid
- acid derivatives
- vincristine
- preparing
- Prior art date
Links
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 title 1
- 229960004528 vincristine Drugs 0.000 title 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU8449A HU190219B (en) | 1984-01-06 | 1984-01-06 | Process for preparing in 3",7'-position cyclized dimer-cinca-alkaloid-derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL73884A0 IL73884A0 (en) | 1985-03-31 |
| IL73884A true IL73884A (en) | 1988-09-30 |
Family
ID=10947652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL73884A IL73884A (en) | 1984-01-06 | 1984-12-20 | Aspidosperimidine-3-carboxylic acid derivatives and their use in preparing vincristine |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4659816A (ja) |
| JP (1) | JPS60174791A (ja) |
| BE (1) | BE901446A (ja) |
| CA (1) | CA1242192A (ja) |
| FR (1) | FR2557877B1 (ja) |
| GB (1) | GB2152506B (ja) |
| HU (1) | HU190219B (ja) |
| IL (1) | IL73884A (ja) |
| SE (1) | SE462685B (ja) |
| ZA (1) | ZA849909B (ja) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2582651B1 (fr) * | 1985-06-03 | 1987-08-28 | Pf Medicament | Procede de preparation de vincristine |
| JPH09314479A (ja) * | 1996-05-28 | 1997-12-09 | Fuji Tekunika:Kk | 位置決めピン用引き抜き装置 |
| JP5046356B2 (ja) * | 2006-01-12 | 2012-10-10 | 株式会社Ｌｉｘｉｌ | 開口部装置 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH434281A (de) * | 1964-03-04 | 1967-04-30 | Geigy Ag J R | Verfahren zur Herstellung von polycyclischen Indolderivaten |
| US3899493A (en) * | 1972-12-29 | 1975-08-12 | Richter Gedeon Vegyeszet | Chromic acid oxidation of vinblastine sulfate to form vincristine |
| US4303584A (en) * | 1980-04-02 | 1981-12-01 | Eli Lilly And Company | Method of preparing vincristine |
| US4375432A (en) * | 1981-05-12 | 1983-03-01 | Eli Lilly And Company | Method of preparing vincristine |
-
1984
- 1984-01-06 HU HU8449A patent/HU190219B/hu not_active IP Right Cessation
- 1984-12-19 ZA ZA849909A patent/ZA849909B/xx unknown
- 1984-12-20 IL IL73884A patent/IL73884A/xx unknown
- 1984-12-28 CA CA000471111A patent/CA1242192A/en not_active Expired
-
1985
- 1985-01-04 JP JP60000019A patent/JPS60174791A/ja active Granted
- 1985-01-04 US US06/688,932 patent/US4659816A/en not_active Expired - Fee Related
- 1985-01-04 BE BE0/214292A patent/BE901446A/fr not_active IP Right Cessation
- 1985-01-04 FR FR858500076A patent/FR2557877B1/fr not_active Expired
- 1985-01-04 SE SE8500040A patent/SE462685B/sv not_active IP Right Cessation
- 1985-01-07 GB GB08500321A patent/GB2152506B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA849909B (en) | 1985-10-30 |
| JPS60174791A (ja) | 1985-09-09 |
| FR2557877A1 (fr) | 1985-07-12 |
| FR2557877B1 (fr) | 1989-06-16 |
| GB2152506A (en) | 1985-08-07 |
| US4659816A (en) | 1987-04-21 |
| JPH0544472B2 (ja) | 1993-07-06 |
| BE901446A (fr) | 1985-07-04 |
| SE462685B (sv) | 1990-08-13 |
| GB2152506B (en) | 1987-12-23 |
| GB8500321D0 (en) | 1985-02-13 |
| HU190219B (en) | 1986-08-28 |
| CA1242192A (en) | 1988-09-20 |
| IL73884A0 (en) | 1985-03-31 |
| SE8500040L (sv) | 1985-07-07 |
| HUT36131A (en) | 1985-08-28 |
| SE8500040D0 (sv) | 1985-01-04 |
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