IL73734A - Process for purifying factor viii:c - Google Patents
Process for purifying factor viii:cInfo
- Publication number
- IL73734A IL73734A IL73734A IL7373484A IL73734A IL 73734 A IL73734 A IL 73734A IL 73734 A IL73734 A IL 73734A IL 7373484 A IL7373484 A IL 7373484A IL 73734 A IL73734 A IL 73734A
- Authority
- IL
- Israel
- Prior art keywords
- factor viii
- purifying factor
- purifying
- purified
- conductivity
- Prior art date
Links
- 229960000301 factor viii Drugs 0.000 title abstract 2
- 229920000936 Agarose Polymers 0.000 abstract 1
- 102000001690 Factor VIII Human genes 0.000 abstract 1
- 108010054218 Factor VIII Proteins 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- -1 aminohexyl Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/557,805 US4508709A (en) | 1983-12-05 | 1983-12-05 | Process for purifying factor VIII:C |
Publications (2)
Publication Number | Publication Date |
---|---|
IL73734A0 IL73734A0 (en) | 1985-03-31 |
IL73734A true IL73734A (en) | 1989-09-28 |
Family
ID=24226953
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL73734A IL73734A (en) | 1983-12-05 | 1984-12-05 | Process for purifying factor viii:c |
Country Status (19)
Country | Link |
---|---|
US (1) | US4508709A (da) |
EP (1) | EP0144957B1 (da) |
JP (1) | JPS60136518A (da) |
KR (1) | KR850004593A (da) |
AT (1) | ATE60996T1 (da) |
AU (1) | AU569129B2 (da) |
CA (1) | CA1248449A (da) |
DE (1) | DE3484179D1 (da) |
DK (1) | DK162896C (da) |
ES (1) | ES8600690A1 (da) |
FI (1) | FI844804L (da) |
IE (1) | IE57644B1 (da) |
IL (1) | IL73734A (da) |
IN (1) | IN162586B (da) |
MX (1) | MX7552E (da) |
NO (1) | NO167627C (da) |
NZ (1) | NZ210427A (da) |
SG (1) | SG14992G (da) |
ZA (1) | ZA849434B (da) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4614795A (en) * | 1982-08-05 | 1986-09-30 | University Of Rochester | Deglycosylated Human Factor VIII:C |
US4650858A (en) * | 1983-03-21 | 1987-03-17 | Nordisk Gentofte A/S | Concentrate of the antihemophilic factor VIII and a process for producing it |
ZA852099B (en) * | 1984-03-26 | 1985-12-24 | Meloy Lab | Recombinant factor viii-c. |
US4965199A (en) * | 1984-04-20 | 1990-10-23 | Genentech, Inc. | Preparation of functional human factor VIII in mammalian cells using methotrexate based selection |
US5043428A (en) * | 1984-08-31 | 1991-08-27 | Behringwerke Aktiengesellschaft | Pasteurized, isoagglutinin-free factor VIII preparation and a process for its production |
DE3432083A1 (de) * | 1984-08-31 | 1986-03-06 | Behringwerke Ag, 3550 Marburg | Pasteurisierte, isoagglutininfreie faktor viii-praeparation und verfahren zu ihrer herstellung |
US4952675A (en) * | 1985-02-01 | 1990-08-28 | New York University | Method for purifying antihemophilic factor |
US4743680A (en) * | 1985-02-01 | 1988-05-10 | New York University | Method for purifying antihemophilic factor |
US4847362A (en) * | 1985-02-01 | 1989-07-11 | New York University | Method for purifying antihemophilic factor |
GB2178533B (en) * | 1985-07-22 | 1989-07-19 | Asahi Chemical Ind | Analytical method of enzyme precursors and device therefor |
JPS63108000A (ja) * | 1986-05-15 | 1988-05-12 | Green Cross Corp:The | 第8因子の精製方法 |
JPH0789951B2 (ja) * | 1986-06-18 | 1995-10-04 | 財団法人阪大微生物病研究会 | 遺伝子発現産物の精製法 |
US4795806A (en) * | 1987-07-16 | 1989-01-03 | Miles Laboratories, Inc. | Phospholipid affinity purification of Factor VIII:C |
NL8701915A (nl) * | 1987-08-14 | 1989-03-01 | Waander Riethorst | Adsorbensmateriaal en toepassing daarvan voor het isoleren van stollingsfaktoren. |
FR2632309B1 (fr) * | 1988-06-07 | 1990-08-24 | Lille Transfusion Sanguine | Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus |
DE3826792C1 (da) * | 1988-08-06 | 1989-07-06 | Biotest Pharma Gmbh, 6072 Dreieich, De | |
ES2053684T3 (es) * | 1988-11-05 | 1994-08-01 | Octapharma Ag | Procedimiento para preparar un factor antihemofilico, altamente puro, no infeccioso, mediante cromatografia. |
FR2644064B1 (fr) * | 1989-02-17 | 1994-05-27 | Aquitaine Dev Transf Sanguine | Procede de fabrication du facteur antihemophilique fviiic ayant une tres haute purete et facteur antihemophilique fviiic ainsi obtenu, ainsi que composition pharmaceutique le contenant |
FR2665449B1 (fr) * | 1990-08-02 | 1995-04-14 | Aquitaine Developp Transf Sang | Procede de fabrication de facteur von willebrand ayant une tres haute purete, depourvu en majeure partie de facteur antihemophilique (fviiic), et facteur von willebrand ainsi obtenu, ainsi qu'une composition pharmaceutique le contenant. |
GB8913183D0 (en) * | 1989-06-08 | 1989-07-26 | Central Blood Lab Authority | Chemical products |
DE3939346A1 (de) * | 1989-11-29 | 1991-06-06 | Behringwerke Ag | Arzneimitel zur subkutanen oder intramuskulaeren applikation enthaltend polypeptide |
JPH0427865A (ja) * | 1989-12-21 | 1992-01-30 | Kurita Water Ind Ltd | 血液凝固因子用分離剤およびその製造方法 |
FR2681867B1 (fr) * | 1991-09-26 | 1993-12-31 | Pasteur Merieux Serums Vaccins | Procede de purification du facteur viii et preparations obtenues. |
US5278289A (en) * | 1991-11-12 | 1994-01-11 | Johnson Alan J | Antihemophilic factor stabilization |
AU7254894A (en) * | 1993-07-23 | 1995-02-20 | Baxter International Inc. | Activated human factor viii and method of preparation |
US5576291A (en) * | 1993-09-13 | 1996-11-19 | Baxter International Inc. | Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency |
US5659017A (en) * | 1995-11-07 | 1997-08-19 | Alpha Therapeutic Corporation | Anion exchange process for the purification of Factor VIII |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4361509A (en) * | 1981-12-14 | 1982-11-30 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
US4397841A (en) * | 1982-06-28 | 1983-08-09 | Monsanto Company | Production of blood coagulation factor VIII:C |
DK525384D0 (da) * | 1984-11-05 | 1984-11-05 | Nordisk Insulinlab | Praeparat paa basis af faktor viii til behandling af haemofili a inhibitorpatienter samt fremgangsmaade til fremstilling af et saadan praeparat |
-
1983
- 1983-12-05 US US06/557,805 patent/US4508709A/en not_active Expired - Lifetime
-
1984
- 1984-11-28 AU AU35982/84A patent/AU569129B2/en not_active Ceased
- 1984-11-29 CA CA000468986A patent/CA1248449A/en not_active Expired
- 1984-11-30 IN IN827/CAL/84A patent/IN162586B/en unknown
- 1984-12-03 DE DE8484114693T patent/DE3484179D1/de not_active Expired - Lifetime
- 1984-12-03 AT AT84114693T patent/ATE60996T1/de not_active IP Right Cessation
- 1984-12-03 EP EP84114693A patent/EP0144957B1/en not_active Expired - Lifetime
- 1984-12-04 ZA ZA849434A patent/ZA849434B/xx unknown
- 1984-12-04 DK DK575184A patent/DK162896C/da not_active IP Right Cessation
- 1984-12-04 NO NO844837A patent/NO167627C/no not_active IP Right Cessation
- 1984-12-04 NZ NZ210427A patent/NZ210427A/xx unknown
- 1984-12-05 JP JP59255863A patent/JPS60136518A/ja active Granted
- 1984-12-05 IL IL73734A patent/IL73734A/xx not_active IP Right Cessation
- 1984-12-05 KR KR1019840007676A patent/KR850004593A/ko not_active Application Discontinuation
- 1984-12-05 FI FI844804A patent/FI844804L/fi not_active Application Discontinuation
- 1984-12-05 MX MX84101943U patent/MX7552E/es unknown
- 1984-12-05 IE IE3105/84A patent/IE57644B1/en not_active IP Right Cessation
- 1984-12-05 ES ES538912A patent/ES8600690A1/es not_active Expired
-
1992
- 1992-02-18 SG SG149/92A patent/SG14992G/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO167627B (no) | 1991-08-19 |
JPH0535159B2 (da) | 1993-05-25 |
SG14992G (en) | 1992-04-16 |
US4508709A (en) | 1985-04-02 |
AU569129B2 (en) | 1988-01-21 |
JPS60136518A (ja) | 1985-07-20 |
DK575184D0 (da) | 1984-12-04 |
IL73734A0 (en) | 1985-03-31 |
NO844837L (no) | 1985-06-06 |
AU3598284A (en) | 1985-06-13 |
ES538912A0 (es) | 1985-11-01 |
CA1248449A (en) | 1989-01-10 |
DK575184A (da) | 1985-06-06 |
FI844804L (fi) | 1985-06-06 |
NZ210427A (en) | 1988-09-29 |
EP0144957A2 (en) | 1985-06-19 |
ZA849434B (en) | 1985-07-31 |
FI844804A0 (fi) | 1984-12-05 |
MX7552E (es) | 1989-09-25 |
EP0144957B1 (en) | 1991-02-27 |
DK162896B (da) | 1991-12-23 |
IE843105L (en) | 1985-06-05 |
EP0144957A3 (en) | 1987-09-30 |
ATE60996T1 (de) | 1991-03-15 |
DE3484179D1 (de) | 1991-04-04 |
IE57644B1 (en) | 1993-02-10 |
KR850004593A (ko) | 1985-07-25 |
IN162586B (da) | 1988-06-11 |
NO167627C (no) | 1991-11-27 |
ES8600690A1 (es) | 1985-11-01 |
DK162896C (da) | 1992-05-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
EXP | Patent expired |