IL73501A - Omega-cycloalkyl prostaglandin derivatives of the pge2 series - Google Patents

Omega-cycloalkyl prostaglandin derivatives of the pge2 series

Info

Publication number
IL73501A
IL73501A IL73501A IL7350184A IL73501A IL 73501 A IL73501 A IL 73501A IL 73501 A IL73501 A IL 73501A IL 7350184 A IL7350184 A IL 7350184A IL 73501 A IL73501 A IL 73501A
Authority
IL
Israel
Prior art keywords
sub
omega
carbon atoms
lower alkyl
prostaglandin derivatives
Prior art date
Application number
IL73501A
Other languages
English (en)
Other versions
IL73501A0 (en
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of IL73501A0 publication Critical patent/IL73501A0/xx
Publication of IL73501A publication Critical patent/IL73501A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL73501A 1983-11-14 1984-11-13 Omega-cycloalkyl prostaglandin derivatives of the pge2 series IL73501A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/551,238 US4499296A (en) 1983-11-14 1983-11-14 Omega cycloalkyl prostaglandins

Publications (2)

Publication Number Publication Date
IL73501A0 IL73501A0 (en) 1985-02-28
IL73501A true IL73501A (en) 1987-12-31

Family

ID=24200423

Family Applications (1)

Application Number Title Priority Date Filing Date
IL73501A IL73501A (en) 1983-11-14 1984-11-13 Omega-cycloalkyl prostaglandin derivatives of the pge2 series

Country Status (16)

Country Link
US (1) US4499296A (ja)
EP (1) EP0142158B1 (ja)
JP (1) JPS60116667A (ja)
AT (1) ATE39481T1 (ja)
AU (1) AU3536084A (ja)
DE (1) DE3475785D1 (ja)
DK (1) DK538984A (ja)
ES (1) ES8603400A1 (ja)
FI (1) FI844460L (ja)
GR (1) GR80926B (ja)
IL (1) IL73501A (ja)
NO (1) NO844528L (ja)
NZ (1) NZ210197A (ja)
PH (1) PH21604A (ja)
PT (1) PT79488A (ja)
ZA (1) ZA848840B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713477A (en) * 1983-11-14 1987-12-15 G. D. Searle & Co. Omega cycloalkyl prostaglandins
GB8410396D0 (en) * 1984-04-24 1984-05-31 Glaxo Group Ltd Carbocyclic compounds
DE3526362A1 (de) * 1985-07-19 1987-01-22 Schering Ag Prostacycline, ihre analoga oder prostaglandine und thromboxanantagonisten zur behandlung von thrombotischen und thromboembolischen krankheitsbildern
EP0213313A3 (en) * 1985-07-29 1988-09-14 American Cyanamid Company Precursors and synthesis of methyl-9-oxo-11 alpha, 16-dihydroxy-16-vinyl-5-cis-13-trans prostadienoates
US4683328A (en) * 1985-11-25 1987-07-28 G. D. Searle & Co. Tetraenyl prostaglandins
US4847293A (en) * 1985-11-25 1989-07-11 G. D. Searle & Co. Tetraenyl prostaglandins
US4820728A (en) * 1985-11-25 1989-04-11 G. D. Searle & Co. Tetraenyl prostaglandins
US4785124A (en) * 1987-06-08 1988-11-15 G. D. Searle & Co. Process for preparing higher order cuprate complexes
US5011958A (en) * 1987-06-08 1991-04-30 G. D. Searle & Co. Process for preparing higher order cuprate complexes
US4777275A (en) * 1987-06-09 1988-10-11 G. D. Searle & Co. Process of preparing higher order cuprate complexes
DK0444844T3 (da) * 1990-02-26 1995-04-03 R Tech Ueno Ltd Hidtil ukendte 15-dehydroxy-16-oxoprostaglandiner
US5177251A (en) * 1991-12-24 1993-01-05 G. D. Searle & Co. Halogenated tetraenyl prostaglandin derivatives
JP2531341Y2 (ja) * 1993-02-25 1997-04-02 小糸工業株式会社 衛生洗浄装置におけるワイヤレスリモコン装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3965143A (en) * 1974-03-26 1976-06-22 G. D. Searle & Co. 16-Oxygenated prostanoic acid derivatives
US4281153A (en) * 1977-08-01 1981-07-28 American Cyanamid 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners
US4275224A (en) * 1978-02-23 1981-06-23 Miles Laboratories, Inc. 15-Deoxy-16-hydroxy prostaglandins
US4271314A (en) * 1979-11-28 1981-06-02 G. D. Searle & Co. 4,5-Unsaturated prostanoic acid derivatives

Also Published As

Publication number Publication date
ES537613A0 (es) 1985-12-16
ATE39481T1 (de) 1989-01-15
JPS60116667A (ja) 1985-06-24
DK538984D0 (da) 1984-11-13
NZ210197A (en) 1988-04-29
EP0142158B1 (en) 1988-12-28
FI844460A0 (fi) 1984-11-13
JPH0576467B2 (ja) 1993-10-22
GR80926B (en) 1985-02-26
DK538984A (da) 1985-05-15
EP0142158A2 (en) 1985-05-22
IL73501A0 (en) 1985-02-28
FI844460A7 (fi) 1985-05-15
EP0142158A3 (en) 1986-09-03
DE3475785D1 (en) 1989-02-02
PT79488A (en) 1984-12-01
PH21604A (en) 1987-12-11
NO844528L (no) 1985-05-15
ES8603400A1 (es) 1985-12-16
FI844460L (fi) 1985-05-15
AU3536084A (en) 1985-05-23
US4499296A (en) 1985-02-12
ZA848840B (en) 1985-12-24

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