ZA848840B - Omega-cycloalkyl prostaglandins - Google Patents

Omega-cycloalkyl prostaglandins

Info

Publication number
ZA848840B
ZA848840B ZA848840A ZA848840A ZA848840B ZA 848840 B ZA848840 B ZA 848840B ZA 848840 A ZA848840 A ZA 848840A ZA 848840 A ZA848840 A ZA 848840A ZA 848840 B ZA848840 B ZA 848840B
Authority
ZA
South Africa
Prior art keywords
sub
carbon atoms
prostaglandins
lower alkyl
cycloalkyl
Prior art date
Application number
ZA848840A
Other languages
English (en)
Inventor
Paul Waddell Collins
Alan Frank Gasiecki
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of ZA848840B publication Critical patent/ZA848840B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA848840A 1983-11-14 1984-11-13 Omega-cycloalkyl prostaglandins ZA848840B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/551,238 US4499296A (en) 1983-11-14 1983-11-14 Omega cycloalkyl prostaglandins

Publications (1)

Publication Number Publication Date
ZA848840B true ZA848840B (en) 1985-12-24

Family

ID=24200423

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA848840A ZA848840B (en) 1983-11-14 1984-11-13 Omega-cycloalkyl prostaglandins

Country Status (16)

Country Link
US (1) US4499296A (xx)
EP (1) EP0142158B1 (xx)
JP (1) JPS60116667A (xx)
AT (1) ATE39481T1 (xx)
AU (1) AU3536084A (xx)
DE (1) DE3475785D1 (xx)
DK (1) DK538984A (xx)
ES (1) ES8603400A1 (xx)
FI (1) FI844460L (xx)
GR (1) GR80926B (xx)
IL (1) IL73501A (xx)
NO (1) NO844528L (xx)
NZ (1) NZ210197A (xx)
PH (1) PH21604A (xx)
PT (1) PT79488A (xx)
ZA (1) ZA848840B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713477A (en) * 1983-11-14 1987-12-15 G. D. Searle & Co. Omega cycloalkyl prostaglandins
GB8410396D0 (en) * 1984-04-24 1984-05-31 Glaxo Group Ltd Carbocyclic compounds
DE3526362A1 (de) * 1985-07-19 1987-01-22 Schering Ag Prostacycline, ihre analoga oder prostaglandine und thromboxanantagonisten zur behandlung von thrombotischen und thromboembolischen krankheitsbildern
EP0213313A3 (en) * 1985-07-29 1988-09-14 American Cyanamid Company Precursors and synthesis of methyl-9-oxo-11 alpha, 16-dihydroxy-16-vinyl-5-cis-13-trans prostadienoates
US4847293A (en) * 1985-11-25 1989-07-11 G. D. Searle & Co. Tetraenyl prostaglandins
US4683328A (en) * 1985-11-25 1987-07-28 G. D. Searle & Co. Tetraenyl prostaglandins
US4820728A (en) * 1985-11-25 1989-04-11 G. D. Searle & Co. Tetraenyl prostaglandins
US4785124A (en) * 1987-06-08 1988-11-15 G. D. Searle & Co. Process for preparing higher order cuprate complexes
US5011958A (en) * 1987-06-08 1991-04-30 G. D. Searle & Co. Process for preparing higher order cuprate complexes
US4777275A (en) * 1987-06-09 1988-10-11 G. D. Searle & Co. Process of preparing higher order cuprate complexes
DK0444844T3 (da) * 1990-02-26 1995-04-03 R Tech Ueno Ltd Hidtil ukendte 15-dehydroxy-16-oxoprostaglandiner
US5177251A (en) * 1991-12-24 1993-01-05 G. D. Searle & Co. Halogenated tetraenyl prostaglandin derivatives
JP2531341Y2 (ja) * 1993-02-25 1997-04-02 小糸工業株式会社 衛生洗浄装置におけるワイヤレスリモコン装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3965143A (en) * 1974-03-26 1976-06-22 G. D. Searle & Co. 16-Oxygenated prostanoic acid derivatives
US4281153A (en) * 1977-08-01 1981-07-28 American Cyanamid 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners
US4275224A (en) * 1978-02-23 1981-06-23 Miles Laboratories, Inc. 15-Deoxy-16-hydroxy prostaglandins
US4271314A (en) * 1979-11-28 1981-06-02 G. D. Searle & Co. 4,5-Unsaturated prostanoic acid derivatives

Also Published As

Publication number Publication date
JPS60116667A (ja) 1985-06-24
PT79488A (en) 1984-12-01
US4499296A (en) 1985-02-12
JPH0576467B2 (xx) 1993-10-22
EP0142158B1 (en) 1988-12-28
PH21604A (en) 1987-12-11
DE3475785D1 (en) 1989-02-02
DK538984A (da) 1985-05-15
ES537613A0 (es) 1985-12-16
NZ210197A (en) 1988-04-29
AU3536084A (en) 1985-05-23
FI844460L (fi) 1985-05-15
ES8603400A1 (es) 1985-12-16
FI844460A0 (fi) 1984-11-13
DK538984D0 (da) 1984-11-13
IL73501A0 (en) 1985-02-28
EP0142158A3 (en) 1986-09-03
EP0142158A2 (en) 1985-05-22
IL73501A (en) 1987-12-31
GR80926B (en) 1985-02-26
NO844528L (no) 1985-05-15
ATE39481T1 (de) 1989-01-15

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