DE3475785D1 - Omega-cycloalkyl prostaglandins - Google Patents
Omega-cycloalkyl prostaglandinsInfo
- Publication number
- DE3475785D1 DE3475785D1 DE8484113676T DE3475785T DE3475785D1 DE 3475785 D1 DE3475785 D1 DE 3475785D1 DE 8484113676 T DE8484113676 T DE 8484113676T DE 3475785 T DE3475785 T DE 3475785T DE 3475785 D1 DE3475785 D1 DE 3475785D1
- Authority
- DE
- Germany
- Prior art keywords
- sub
- carbon atoms
- prostaglandins
- lower alkyl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940094443 oxytocics prostaglandins Drugs 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 1
- 125000000350 glycoloyl group Chemical group O=C([*])C([H])([H])O[H] 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/551,238 US4499296A (en) | 1983-11-14 | 1983-11-14 | Omega cycloalkyl prostaglandins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3475785D1 true DE3475785D1 (en) | 1989-02-02 |
Family
ID=24200423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8484113676T Expired DE3475785D1 (en) | 1983-11-14 | 1984-11-13 | Omega-cycloalkyl prostaglandins |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4499296A (de) |
| EP (1) | EP0142158B1 (de) |
| JP (1) | JPS60116667A (de) |
| AT (1) | ATE39481T1 (de) |
| AU (1) | AU3536084A (de) |
| DE (1) | DE3475785D1 (de) |
| DK (1) | DK538984A (de) |
| ES (1) | ES8603400A1 (de) |
| FI (1) | FI844460L (de) |
| GR (1) | GR80926B (de) |
| IL (1) | IL73501A (de) |
| NO (1) | NO844528L (de) |
| NZ (1) | NZ210197A (de) |
| PH (1) | PH21604A (de) |
| PT (1) | PT79488A (de) |
| ZA (1) | ZA848840B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4713477A (en) * | 1983-11-14 | 1987-12-15 | G. D. Searle & Co. | Omega cycloalkyl prostaglandins |
| GB8410396D0 (en) * | 1984-04-24 | 1984-05-31 | Glaxo Group Ltd | Carbocyclic compounds |
| DE3526362A1 (de) * | 1985-07-19 | 1987-01-22 | Schering Ag | Prostacycline, ihre analoga oder prostaglandine und thromboxanantagonisten zur behandlung von thrombotischen und thromboembolischen krankheitsbildern |
| EP0213313A3 (de) * | 1985-07-29 | 1988-09-14 | American Cyanamid Company | Vorläufer und Synthese von 9-oxo-11-alpha-16-dihydroxy-16-vinyl-5-cis-13-transmethylprostadienoate |
| US4820728A (en) * | 1985-11-25 | 1989-04-11 | G. D. Searle & Co. | Tetraenyl prostaglandins |
| US4847293A (en) * | 1985-11-25 | 1989-07-11 | G. D. Searle & Co. | Tetraenyl prostaglandins |
| US4683328A (en) * | 1985-11-25 | 1987-07-28 | G. D. Searle & Co. | Tetraenyl prostaglandins |
| US5011958A (en) * | 1987-06-08 | 1991-04-30 | G. D. Searle & Co. | Process for preparing higher order cuprate complexes |
| US4785124A (en) * | 1987-06-08 | 1988-11-15 | G. D. Searle & Co. | Process for preparing higher order cuprate complexes |
| US4777275A (en) * | 1987-06-09 | 1988-10-11 | G. D. Searle & Co. | Process of preparing higher order cuprate complexes |
| ES2069821T3 (es) * | 1990-02-26 | 1995-05-16 | R Tech Ueno Ltd | Nuevas 15-deshidroxi-16-oxoprostaglandinas. |
| US5177251A (en) * | 1991-12-24 | 1993-01-05 | G. D. Searle & Co. | Halogenated tetraenyl prostaglandin derivatives |
| JP2531341Y2 (ja) * | 1993-02-25 | 1997-04-02 | 小糸工業株式会社 | 衛生洗浄装置におけるワイヤレスリモコン装置 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3965143A (en) * | 1974-03-26 | 1976-06-22 | G. D. Searle & Co. | 16-Oxygenated prostanoic acid derivatives |
| US4281153A (en) * | 1977-08-01 | 1981-07-28 | American Cyanamid | 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners |
| US4275224A (en) * | 1978-02-23 | 1981-06-23 | Miles Laboratories, Inc. | 15-Deoxy-16-hydroxy prostaglandins |
| US4271314A (en) * | 1979-11-28 | 1981-06-02 | G. D. Searle & Co. | 4,5-Unsaturated prostanoic acid derivatives |
-
1983
- 1983-11-14 US US06/551,238 patent/US4499296A/en not_active Expired - Lifetime
-
1984
- 1984-11-13 EP EP84113676A patent/EP0142158B1/de not_active Expired
- 1984-11-13 AU AU35360/84A patent/AU3536084A/en not_active Abandoned
- 1984-11-13 NO NO844528A patent/NO844528L/no unknown
- 1984-11-13 DK DK538984A patent/DK538984A/da not_active Application Discontinuation
- 1984-11-13 JP JP59239323A patent/JPS60116667A/ja active Granted
- 1984-11-13 NZ NZ210197A patent/NZ210197A/en unknown
- 1984-11-13 AT AT84113676T patent/ATE39481T1/de not_active IP Right Cessation
- 1984-11-13 ES ES537613A patent/ES8603400A1/es not_active Expired
- 1984-11-13 FI FI844460A patent/FI844460L/fi not_active Application Discontinuation
- 1984-11-13 IL IL73501A patent/IL73501A/xx unknown
- 1984-11-13 DE DE8484113676T patent/DE3475785D1/de not_active Expired
- 1984-11-13 ZA ZA848840A patent/ZA848840B/xx unknown
- 1984-11-13 PT PT79488A patent/PT79488A/pt unknown
- 1984-11-13 PH PH31444A patent/PH21604A/en unknown
- 1984-11-13 GR GR80926A patent/GR80926B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI844460A0 (fi) | 1984-11-13 |
| FI844460L (fi) | 1985-05-15 |
| ATE39481T1 (de) | 1989-01-15 |
| GR80926B (en) | 1985-02-26 |
| EP0142158A3 (en) | 1986-09-03 |
| ES537613A0 (es) | 1985-12-16 |
| IL73501A0 (en) | 1985-02-28 |
| JPH0576467B2 (de) | 1993-10-22 |
| EP0142158A2 (de) | 1985-05-22 |
| NO844528L (no) | 1985-05-15 |
| DK538984A (da) | 1985-05-15 |
| ZA848840B (en) | 1985-12-24 |
| DK538984D0 (da) | 1984-11-13 |
| US4499296A (en) | 1985-02-12 |
| PH21604A (en) | 1987-12-11 |
| EP0142158B1 (de) | 1988-12-28 |
| IL73501A (en) | 1987-12-31 |
| JPS60116667A (ja) | 1985-06-24 |
| AU3536084A (en) | 1985-05-23 |
| PT79488A (en) | 1984-12-01 |
| ES8603400A1 (es) | 1985-12-16 |
| NZ210197A (en) | 1988-04-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |