IL72529A - (hetero)aryl-(1,2,4)triazolo(1,5-c)pyrimidin-2-amines and antianaphylactic pharmaceutical compositions containing them - Google Patents

(hetero)aryl-(1,2,4)triazolo(1,5-c)pyrimidin-2-amines and antianaphylactic pharmaceutical compositions containing them

Info

Publication number
IL72529A
IL72529A IL72529A IL7252984A IL72529A IL 72529 A IL72529 A IL 72529A IL 72529 A IL72529 A IL 72529A IL 7252984 A IL7252984 A IL 7252984A IL 72529 A IL72529 A IL 72529A
Authority
IL
Israel
Prior art keywords
triazolo
pyrimidin
amines
antianaphylactic
hetero
Prior art date
Application number
IL72529A
Other languages
English (en)
Other versions
IL72529A0 (en
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of IL72529A0 publication Critical patent/IL72529A0/xx
Publication of IL72529A publication Critical patent/IL72529A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/34One oxygen atom
    • C07D239/36One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL72529A 1983-07-28 1984-07-27 (hetero)aryl-(1,2,4)triazolo(1,5-c)pyrimidin-2-amines and antianaphylactic pharmaceutical compositions containing them IL72529A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51825083A 1983-07-28 1983-07-28

Publications (2)

Publication Number Publication Date
IL72529A0 IL72529A0 (en) 1984-11-30
IL72529A true IL72529A (en) 1988-05-31

Family

ID=24063190

Family Applications (1)

Application Number Title Priority Date Filing Date
IL72529A IL72529A (en) 1983-07-28 1984-07-27 (hetero)aryl-(1,2,4)triazolo(1,5-c)pyrimidin-2-amines and antianaphylactic pharmaceutical compositions containing them

Country Status (18)

Country Link
EP (1) EP0132851B1 (xx)
JP (1) JPS6056983A (xx)
KR (1) KR900004000B1 (xx)
AT (1) ATE46907T1 (xx)
AU (1) AU570989B2 (xx)
CA (1) CA1224785A (xx)
DD (1) DD220780A5 (xx)
DE (1) DE3427823A1 (xx)
DK (1) DK365284A (xx)
ES (1) ES8505684A1 (xx)
GR (1) GR82440B (xx)
HK (1) HK4391A (xx)
HU (1) HU190936B (xx)
IE (1) IE57939B1 (xx)
IL (1) IL72529A (xx)
NZ (1) NZ208996A (xx)
PL (1) PL248968A1 (xx)
ZA (1) ZA845842B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0244948A3 (en) * 1986-04-30 1989-03-15 Schering Agrochemicals Limited Triazolopyrimidine herbicides
CA2284737C (en) 1997-03-24 2007-03-13 Kyowa Hakko Kogyo Co., Ltd. [1,2,4]triazolo[1,5-c]pyrimidine derivatives
BR9914040A (pt) 1998-09-22 2002-01-15 Kyowa Hakko Kogyo Kk Derivados de [1,2,4]triazolo[1,5-c]pirimidina e seu uso, medicamento, antagonista, agente para prevenir ou tratar doenças, bem como processo para prevenção ou tratamento de distúrbios
GB0719803D0 (en) * 2007-10-10 2007-11-21 Cancer Rec Tech Ltd Therapeutic compounds and their use
TWI462920B (zh) 2009-06-26 2014-12-01 葛萊伯格有限公司 用於治療退化性及發炎疾病之新穎化合物
PL2851367T3 (pl) * 2010-05-25 2017-05-31 Dow Agrosciences, Llc Sposób wytwarzania 2-amino-5,8-alkoksy[1,2,4]triazolo[1,5-c]pirymidyny przez reakcję 5-halogeno-8-alkoksy[1,2,4]triazolo[1,5-c]pirymidyno-2-aminy z alkoholanem metalu alkalicznego w alkoholowym rozpuszczalniku
KR102629882B1 (ko) * 2023-05-10 2024-01-29 김황래 조적수평장치

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3045015A (en) * 1958-10-03 1962-07-17 Ici Ltd Triazolo-[2, 3-c]-pyrimidines
US3053844A (en) * 1959-04-13 1962-09-11 Ici Ltd Mono-acyl derivatives of s-triazolo [2, 3-c] pyrimidines
US3046276A (en) * 1959-06-15 1962-07-24 Ici Ltd S-triazolo-[2, 3-c] pyrimidine derivatives
US4269980A (en) * 1979-12-17 1981-05-26 American Cyanamid Company (Substituted-phenyl)-1,2,4-triazolo[4,3-c]pyrimidines and (substituted-phenyl)-1,2,4-triazolo[1,5-c]pyrimidines

Also Published As

Publication number Publication date
EP0132851B1 (en) 1989-10-04
ES534681A0 (es) 1985-06-16
IE841943L (en) 1985-01-25
ZA845842B (en) 1985-03-27
DD220780A5 (de) 1985-04-10
ES8505684A1 (es) 1985-06-16
EP0132851A1 (en) 1985-02-13
DK365284A (da) 1985-01-29
JPH0447671B2 (xx) 1992-08-04
JPS6056983A (ja) 1985-04-02
DK365284D0 (da) 1984-07-26
KR850001215A (ko) 1985-03-16
PL248968A1 (en) 1985-10-22
HUT34752A (en) 1985-04-28
KR900004000B1 (ko) 1990-06-07
CA1224785A (en) 1987-07-28
AU3124084A (en) 1985-01-31
IL72529A0 (en) 1984-11-30
NZ208996A (en) 1989-08-29
IE57939B1 (en) 1993-05-19
DE3427823A1 (de) 1985-02-07
HU190936B (en) 1986-12-28
GR82440B (xx) 1984-12-13
ATE46907T1 (de) 1989-10-15
HK4391A (en) 1991-01-18
AU570989B2 (en) 1988-03-31

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