IL72324A - Pyrrolidinones,their preparation and pharmaceutical compositions containing them - Google Patents

Pyrrolidinones,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL72324A
IL72324A IL72324A IL7232484A IL72324A IL 72324 A IL72324 A IL 72324A IL 72324 A IL72324 A IL 72324A IL 7232484 A IL7232484 A IL 7232484A IL 72324 A IL72324 A IL 72324A
Authority
IL
Israel
Prior art keywords
pyrrolidinones
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
IL72324A
Other languages
English (en)
Other versions
IL72324A0 (en
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of IL72324A0 publication Critical patent/IL72324A0/xx
Publication of IL72324A publication Critical patent/IL72324A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/50—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C205/51—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07F9/6533—Six-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL72324A 1983-07-12 1984-07-06 Pyrrolidinones,their preparation and pharmaceutical compositions containing them IL72324A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8311636A FR2549053B1 (fr) 1983-07-12 1983-07-12 Nouveaux derives de la pyrrolidine actifs sur le systeme nerveux central, leur procede de preparation, les medicaments en contenant

Publications (2)

Publication Number Publication Date
IL72324A0 IL72324A0 (en) 1984-11-30
IL72324A true IL72324A (en) 1987-10-30

Family

ID=9290775

Family Applications (1)

Application Number Title Priority Date Filing Date
IL72324A IL72324A (en) 1983-07-12 1984-07-06 Pyrrolidinones,their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (1) US4604383A (OSRAM)
EP (1) EP0135406B1 (OSRAM)
JP (1) JPS6084265A (OSRAM)
KR (1) KR910003362B1 (OSRAM)
AR (1) AR240451A1 (OSRAM)
AT (1) ATE30150T1 (OSRAM)
AU (1) AU560725B2 (OSRAM)
CA (1) CA1249593A (OSRAM)
DD (2) DD229121A5 (OSRAM)
DE (1) DE3466686D1 (OSRAM)
DK (1) DK343784A (OSRAM)
ES (1) ES534221A0 (OSRAM)
FI (1) FI77848C (OSRAM)
FR (1) FR2549053B1 (OSRAM)
GR (1) GR81502B (OSRAM)
HU (1) HU192564B (OSRAM)
IL (1) IL72324A (OSRAM)
NO (1) NO163617C (OSRAM)
NZ (1) NZ208865A (OSRAM)
PT (1) PT78874B (OSRAM)
SU (1) SU1391497A3 (OSRAM)
YU (2) YU121384A (OSRAM)
ZA (1) ZA845397B (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
CA1336333C (en) * 1988-05-20 1995-07-18 Davide Della Bella Pyrrolidone-2 compounds and their use for central analgesic activity
GB9307431D0 (en) * 1993-04-08 1993-06-02 Oxford Asymmetry Ltd Improvements in or relating to chiral auxiliaries
CN106977415B (zh) * 2016-01-15 2021-03-26 广东东阳光药业有限公司 一种沙库必曲的中间体及其制备方法
EP3424899B1 (en) 2016-02-29 2022-05-11 Sunshine Lake Pharma Co., Ltd. Sacubitril intermediate and preparation method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3272842A (en) * 1965-06-25 1966-09-13 Lilly Co Eli Novel pyrrolinones
AU518986B2 (en) * 1977-10-11 1981-10-29 Takeda Chemical Industries Ltd. Lactams
FR2436779A1 (fr) * 1978-09-22 1980-04-18 Pharmindustrie Derives de pyrrolidine-2 methanol utilisables comme medicaments

Also Published As

Publication number Publication date
NZ208865A (en) 1986-12-05
DK343784A (da) 1985-01-13
FR2549053B1 (fr) 1985-12-27
YU121384A (en) 1986-10-31
GR81502B (OSRAM) 1984-12-11
KR850001165A (ko) 1985-03-16
SU1391497A3 (ru) 1988-04-23
AR240451A1 (es) 1990-04-30
ES8504122A1 (es) 1985-04-16
DK343784D0 (da) 1984-07-12
DD227962A5 (de) 1985-10-02
FI77848B (fi) 1989-01-31
IL72324A0 (en) 1984-11-30
EP0135406B1 (fr) 1987-10-07
NO842821L (no) 1985-01-14
HUT34443A (en) 1985-03-28
JPS6084265A (ja) 1985-05-13
DD229121A5 (de) 1985-10-30
KR910003362B1 (ko) 1991-05-28
ATE30150T1 (de) 1987-10-15
YU81086A (en) 1986-10-31
FI77848C (fi) 1989-05-10
FR2549053A1 (fr) 1985-01-18
AU560725B2 (en) 1987-04-16
PT78874A (fr) 1984-08-01
NO163617C (no) 1990-06-27
US4604383A (en) 1986-08-05
AU3021684A (en) 1985-01-17
FI842795A0 (fi) 1984-07-11
ES534221A0 (es) 1985-04-16
DE3466686D1 (en) 1987-11-12
NO163617B (no) 1990-03-19
EP0135406A1 (fr) 1985-03-27
PT78874B (fr) 1986-06-02
HU192564B (en) 1987-06-29
FI842795A7 (fi) 1985-01-13
CA1249593A (en) 1989-01-31
ZA845397B (en) 1985-02-27

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