IL71788A - 6-phenyl-3(2h)pyridazinones(thiones),processes for their preparation and pharmaceutical compositions containing the same - Google Patents
6-phenyl-3(2h)pyridazinones(thiones),processes for their preparation and pharmaceutical compositions containing the sameInfo
- Publication number
- IL71788A IL71788A IL71788A IL7178884A IL71788A IL 71788 A IL71788 A IL 71788A IL 71788 A IL71788 A IL 71788A IL 7178884 A IL7178884 A IL 7178884A IL 71788 A IL71788 A IL 71788A
- Authority
- IL
- Israel
- Prior art keywords
- pyridazinones
- pct
- processes
- preparation
- thiones
- Prior art date
Links
- 241001061127 Thione Species 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000000572 bronchospasmolytic effect Effects 0.000 abstract 1
- 239000000496 cardiotonic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/18—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH258183 | 1983-05-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL71788A0 IL71788A0 (en) | 1984-09-30 |
| IL71788A true IL71788A (en) | 1987-09-16 |
Family
ID=4237009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL71788A IL71788A (en) | 1983-05-11 | 1984-05-10 | 6-phenyl-3(2h)pyridazinones(thiones),processes for their preparation and pharmaceutical compositions containing the same |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4707481A (forum.php) |
| EP (1) | EP0125636B1 (forum.php) |
| JP (1) | JPS60501258A (forum.php) |
| AT (1) | ATE26266T1 (forum.php) |
| AU (1) | AU560607B2 (forum.php) |
| CA (1) | CA1247100A (forum.php) |
| DE (2) | DE3417391A1 (forum.php) |
| DK (1) | DK156655C (forum.php) |
| ES (1) | ES532337A0 (forum.php) |
| GR (1) | GR82072B (forum.php) |
| IL (1) | IL71788A (forum.php) |
| NZ (1) | NZ208107A (forum.php) |
| PT (1) | PT78566B (forum.php) |
| WO (1) | WO1984004521A1 (forum.php) |
| ZA (1) | ZA843520B (forum.php) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK159431C (da) * | 1984-05-10 | 1991-03-18 | Byk Gulden Lomberg Chem Fab | 6-phenyl-3(2h)-pyridazinoner, fremgangsmaade til fremstilling deraf, laegemidler indeholdende disse samt anvendelse af forbindelserne til fremstilling af laegemidler |
| IL79280A (en) * | 1985-07-05 | 1990-07-12 | Smith Kline French Lab | 4-(6-oxo-dihydro or tetrahydropyridazin-3-yl)benzene derivatives,their preparation and pharmaceutical compositions containing them |
| DE3827362A1 (de) * | 1988-08-12 | 1990-02-15 | Basf Ag | Pulvrige, hydrophile theophyllinformulierung und verfahren zur ihrer herstellung |
| EP0393500A1 (de) * | 1989-04-17 | 1990-10-24 | Byk Gulden Lomberg Chemische Fabrik GmbH | Neue Arylpyridazine, ihre Herstellung, Verwendung und sie enthaltende Arzneimittel |
| AU8722991A (en) * | 1990-10-16 | 1992-05-20 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Arylpyridazinones |
| EP0581805A1 (de) * | 1991-04-26 | 1994-02-09 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Neue pyridazine |
| DE59207016D1 (de) * | 1991-07-05 | 1996-10-02 | Byk Gulden Lomberg Chem Fab | Verwendung substituierter pyridazine gegen dermatosen |
| US5814651A (en) * | 1992-12-02 | 1998-09-29 | Pfizer Inc. | Catechol diethers as selective PDEIV inhibitors |
| KR950704228A (ko) * | 1992-12-02 | 1995-11-17 | 알렌 제이. 스피겔 | 선택적 포스포디에스테르가수분해효소 iv형(pde_iv) 저해제로서의 카테콜 디에테르(catecol diethers as selective pde_iv inhibitors) |
| DE19514568A1 (de) * | 1995-04-20 | 1996-10-24 | Merck Patent Gmbh | Arylalkyl-pyridazinone |
| BR9807399B1 (pt) * | 1997-02-17 | 2011-04-19 | composição para o tratamento de sìndrome da angústia respiratória infantil (irds) ou sìndrome da angústia respiratória aguda (ards) compreendendo 3-(ciclopropilmetóxi)-n-(3,5-dicloro-4-piridinil)-4-(difl uorometóxi) benzamida e tensoativo do pulmão, e seu uso. | |
| US7437192B2 (en) * | 2005-04-05 | 2008-10-14 | Pacesetter, Inc. | System and method for detecting heart failure and pulmonary edema based on ventricular end-diastolic pressure using an implantable medical device |
| KR20100016073A (ko) * | 2007-04-02 | 2010-02-12 | 인스티튜트 포 원월드 헬스 | Ｃｆｔｒ 억제제 화합물 및 이의 용도 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT343125B (de) * | 1976-03-24 | 1978-05-10 | Chemie Linz Ag | Verfahren zur herstellung von 3-phenylpyridazon- (6) |
| JPS6037101B2 (ja) * | 1977-03-09 | 1985-08-24 | 三共株式会社 | フエニルピリダジノン誘導体の製法 |
| US4397854A (en) * | 1981-05-14 | 1983-08-09 | Warner-Lambert Company | Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents |
| JPS588015A (ja) * | 1981-07-06 | 1983-01-18 | Mitsubishi Chem Ind Ltd | 強心剤 |
-
1984
- 1984-05-09 GR GR74656A patent/GR82072B/el unknown
- 1984-05-09 PT PT78566A patent/PT78566B/pt not_active IP Right Cessation
- 1984-05-09 ES ES532337A patent/ES532337A0/es active Granted
- 1984-05-09 NZ NZ208107A patent/NZ208107A/en unknown
- 1984-05-10 AT AT84105291T patent/ATE26266T1/de not_active IP Right Cessation
- 1984-05-10 IL IL71788A patent/IL71788A/xx unknown
- 1984-05-10 EP EP84105291A patent/EP0125636B1/de not_active Expired
- 1984-05-10 AU AU29617/84A patent/AU560607B2/en not_active Ceased
- 1984-05-10 ZA ZA843520A patent/ZA843520B/xx unknown
- 1984-05-10 US US06/690,655 patent/US4707481A/en not_active Expired - Fee Related
- 1984-05-10 WO PCT/EP1984/000139 patent/WO1984004521A1/de unknown
- 1984-05-10 JP JP59502040A patent/JPS60501258A/ja active Pending
- 1984-05-10 DE DE3417391A patent/DE3417391A1/de not_active Withdrawn
- 1984-05-10 DE DE8484105291T patent/DE3462890D1/de not_active Expired
- 1984-05-11 CA CA000454099A patent/CA1247100A/en not_active Expired
-
1985
- 1985-01-10 DK DK012485A patent/DK156655C/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL71788A0 (en) | 1984-09-30 |
| EP0125636A1 (de) | 1984-11-21 |
| DE3417391A1 (de) | 1984-11-15 |
| PT78566A (de) | 1984-06-01 |
| NZ208107A (en) | 1986-12-05 |
| JPS60501258A (ja) | 1985-08-08 |
| ATE26266T1 (de) | 1987-04-15 |
| GR82072B (forum.php) | 1984-12-13 |
| ZA843520B (en) | 1984-12-24 |
| AU2961784A (en) | 1984-12-04 |
| PT78566B (de) | 1986-07-17 |
| CA1247100A (en) | 1988-12-20 |
| DE3462890D1 (en) | 1987-05-07 |
| ES8601918A1 (es) | 1985-12-01 |
| DK156655B (da) | 1989-09-18 |
| AU560607B2 (en) | 1987-04-09 |
| DK156655C (da) | 1990-02-05 |
| DK12485D0 (da) | 1985-01-10 |
| EP0125636B1 (de) | 1987-04-01 |
| DK12485A (da) | 1985-01-10 |
| WO1984004521A1 (en) | 1984-11-22 |
| US4707481A (en) | 1987-11-17 |
| ES532337A0 (es) | 1985-12-01 |
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