IL70111A - 3-cyano-5-phenoxy(or phenyl-thio)indole derivatives,their preparation and pharmaceutical compositions comprising them - Google Patents
3-cyano-5-phenoxy(or phenyl-thio)indole derivatives,their preparation and pharmaceutical compositions comprising themInfo
- Publication number
- IL70111A IL70111A IL70111A IL7011183A IL70111A IL 70111 A IL70111 A IL 70111A IL 70111 A IL70111 A IL 70111A IL 7011183 A IL7011183 A IL 7011183A IL 70111 A IL70111 A IL 70111A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- phenyl
- indole derivatives
- thio
- phenoxy
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000003356 phenylsulfanyl group Chemical group [*]SC1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 title 1
- 150000002475 indoles Chemical class 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001093 anti-cancer Effects 0.000 abstract 1
- 229940054051 antipsychotic indole derivative Drugs 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8230765 | 1982-10-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL70111A0 IL70111A0 (en) | 1984-02-29 |
| IL70111A true IL70111A (en) | 1987-11-30 |
Family
ID=10533882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL70111A IL70111A (en) | 1982-10-28 | 1983-11-01 | 3-cyano-5-phenoxy(or phenyl-thio)indole derivatives,their preparation and pharmaceutical compositions comprising them |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4533672A (en:Method) |
| EP (1) | EP0107963B1 (en:Method) |
| JP (1) | JPS5995257A (en:Method) |
| AT (1) | ATE26261T1 (en:Method) |
| AU (1) | AU563413B2 (en:Method) |
| CA (1) | CA1205078A (en:Method) |
| DE (1) | DE3370619D1 (en:Method) |
| ES (1) | ES8504707A1 (en:Method) |
| FI (1) | FI77653C (en:Method) |
| GR (1) | GR79404B (en:Method) |
| IE (1) | IE56125B1 (en:Method) |
| IL (1) | IL70111A (en:Method) |
| NO (1) | NO163226C (en:Method) |
| NZ (1) | NZ206080A (en:Method) |
| PT (1) | PT77574B (en:Method) |
| ZA (1) | ZA837829B (en:Method) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5935399A (en) * | 1996-01-31 | 1999-08-10 | Denso Corporation | Air-fuel ratio sensor |
| KR20030013433A (ko) | 2000-05-31 | 2003-02-14 | 아스트라제네카 아베 | 혈관 손상 활성을 가진 인돌 유도체 |
| JP2005532280A (ja) * | 2002-04-03 | 2005-10-27 | アストラゼネカ アクチボラグ | 化合物 |
| CN103242238B (zh) * | 2013-05-10 | 2016-04-20 | 常州齐晖药业有限公司 | 一种芬苯达唑的制备方法 |
| CN105152994A (zh) * | 2015-09-28 | 2015-12-16 | 浙江汇能动物药品有限公司 | 一种芬苯达唑中间体2-氯-4-苯硫基硝基苯的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT246736B (de) * | 1963-03-29 | 1966-05-10 | Byk Gulden Lomberg Chem Fab | Verfahren zur Herstellung neuer, basischer Derivate von substituierten Indol-3-carbonsäuren und deren Salzen |
| FR2131826A1 (en) * | 1971-03-29 | 1972-11-17 | Anvar | 3-carbonyl and thiocarbonyl-2-aminoindoles - with sedative activity |
| BE793358A (fr) * | 1971-12-27 | 1973-06-27 | Hoechst Ag | Nouveaux derives de 2-carbalcoxy-amino-benzimidazole presentantune activite anthelmintique et leur procede de preparation |
-
1983
- 1983-10-20 ZA ZA837829A patent/ZA837829B/xx unknown
- 1983-10-20 IE IE2466/83A patent/IE56125B1/xx unknown
- 1983-10-24 US US06/545,010 patent/US4533672A/en not_active Expired - Fee Related
- 1983-10-24 AT AT83306439T patent/ATE26261T1/de not_active IP Right Cessation
- 1983-10-24 EP EP83306439A patent/EP0107963B1/en not_active Expired
- 1983-10-24 DE DE8383306439T patent/DE3370619D1/de not_active Expired
- 1983-10-25 AU AU20548/83A patent/AU563413B2/en not_active Ceased
- 1983-10-25 GR GR72779A patent/GR79404B/el unknown
- 1983-10-27 PT PT77574A patent/PT77574B/pt not_active IP Right Cessation
- 1983-10-27 NZ NZ206080A patent/NZ206080A/en unknown
- 1983-10-27 CA CA000439878A patent/CA1205078A/en not_active Expired
- 1983-10-27 NO NO833918A patent/NO163226C/no unknown
- 1983-10-28 JP JP58201152A patent/JPS5995257A/ja active Pending
- 1983-10-28 FI FI833958A patent/FI77653C/fi not_active IP Right Cessation
- 1983-10-28 ES ES526876A patent/ES8504707A1/es not_active Expired
- 1983-11-01 IL IL70111A patent/IL70111A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5995257A (ja) | 1984-06-01 |
| DE3370619D1 (de) | 1987-05-07 |
| NO163226C (no) | 1990-04-25 |
| FI77653C (fi) | 1989-04-10 |
| IE56125B1 (en) | 1991-04-24 |
| CA1205078A (en) | 1986-05-27 |
| ES526876A0 (es) | 1985-05-01 |
| NO833918L (no) | 1984-04-30 |
| ES8504707A1 (es) | 1985-05-01 |
| EP0107963B1 (en) | 1987-04-01 |
| ZA837829B (en) | 1984-08-29 |
| IE832466L (en) | 1984-04-28 |
| EP0107963A1 (en) | 1984-05-09 |
| NO163226B (no) | 1990-01-15 |
| AU2054883A (en) | 1984-05-03 |
| AU563413B2 (en) | 1987-07-09 |
| NZ206080A (en) | 1987-01-23 |
| FI77653B (fi) | 1988-12-30 |
| PT77574A (en) | 1983-11-01 |
| GR79404B (en:Method) | 1984-10-22 |
| FI833958L (fi) | 1984-04-29 |
| US4533672A (en) | 1985-08-06 |
| IL70111A0 (en) | 1984-02-29 |
| ATE26261T1 (de) | 1987-04-15 |
| FI833958A0 (fi) | 1983-10-28 |
| PT77574B (en) | 1986-03-18 |
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