IL69628A - 4-hydroxy-2-methyl-3-(2-pyridyl-carbamoyl)-6-trifluoro-methyl-2h-thieno(2,3-e)thiazine derivatives,their manufacture and pharmaceutical compositions containing them,and intermediates therefor - Google Patents

4-hydroxy-2-methyl-3-(2-pyridyl-carbamoyl)-6-trifluoro-methyl-2h-thieno(2,3-e)thiazine derivatives,their manufacture and pharmaceutical compositions containing them,and intermediates therefor

Info

Publication number
IL69628A
IL69628A IL69628A IL6962883A IL69628A IL 69628 A IL69628 A IL 69628A IL 69628 A IL69628 A IL 69628A IL 6962883 A IL6962883 A IL 6962883A IL 69628 A IL69628 A IL 69628A
Authority
IL
Israel
Prior art keywords
methyl
thieno
hydroxy
trifluoro
carbamoyl
Prior art date
Application number
IL69628A
Other languages
English (en)
Other versions
IL69628A0 (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL69628A0 publication Critical patent/IL69628A0/xx
Publication of IL69628A publication Critical patent/IL69628A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL69628A 1982-09-09 1983-09-02 4-hydroxy-2-methyl-3-(2-pyridyl-carbamoyl)-6-trifluoro-methyl-2h-thieno(2,3-e)thiazine derivatives,their manufacture and pharmaceutical compositions containing them,and intermediates therefor IL69628A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH537782 1982-09-09

Publications (2)

Publication Number Publication Date
IL69628A0 IL69628A0 (en) 1983-12-30
IL69628A true IL69628A (en) 1986-09-30

Family

ID=4292544

Family Applications (1)

Application Number Title Priority Date Filing Date
IL69628A IL69628A (en) 1982-09-09 1983-09-02 4-hydroxy-2-methyl-3-(2-pyridyl-carbamoyl)-6-trifluoro-methyl-2h-thieno(2,3-e)thiazine derivatives,their manufacture and pharmaceutical compositions containing them,and intermediates therefor

Country Status (13)

Country Link
US (1) US4544655A (xx)
EP (1) EP0103142B1 (xx)
JP (1) JPS5967292A (xx)
AT (1) ATE26720T1 (xx)
AU (1) AU560973B2 (xx)
CA (1) CA1217187A (xx)
DE (1) DE3371082D1 (xx)
DK (1) DK155009C (xx)
IE (1) IE55942B1 (xx)
IL (1) IL69628A (xx)
NZ (1) NZ205475A (xx)
PH (1) PH19692A (xx)
ZA (1) ZA836546B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL87951A (en) * 1987-10-29 1992-03-29 Chem Pharm Forsch Gmbh Carbonic acid esters of 6-chloro-4-(1-hydroxyethoxy)-2-methyl-n-(2-pyridyl)-2h-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide,their preparation and pharmaceutical compositions containing them
ATA39088A (de) 1988-02-18 1990-06-15 Binder Dieter Dr Basisch substituierte thienoisothiazol-3(2h)-on-1,1-dioxide und ihre pharmazeutisch vertraeglichen salze, verfahren zu ihrer herstellung und ihre verwendung
AT399880B (de) * 1992-07-03 1995-08-25 Chem Pharm Forsch Gmbh Neue thienothiazinderivate, verfahren zu ihrer herstellung und ihre verwendung
EP0658559A1 (de) * 1993-12-14 1995-06-21 Chemisch Pharmazeutische Forschungsgesellschaft m.b.H. Thienothiazinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als 5-dipoxygenase und Cyclooxygenaseinhibitoren
US8329924B2 (en) * 2001-06-11 2012-12-11 Vertex Pharmaceuticals (Canada) Incorporated Compounds and methods for the treatment or prevention of Flavivirus infections
EP2206709A3 (en) * 2001-06-11 2011-06-29 Virochem Pharma Inc. Thiophene derivatives as antiviral agents for flavivirus infection
AT413944B (de) * 2003-05-27 2006-07-15 Binder Eva Dkfm Verwendung von oxicam-verbindungen
US7109232B2 (en) * 2004-03-08 2006-09-19 Simpson Biotech Co., Ltd. Compounds from Antrodia camphorata having anti-inflammatory and anti-tumor activity
CA2746055C (en) * 2008-12-16 2016-12-13 Sunovion Pharmaceuticals Inc. Triple reuptake inhibitors and methods of their use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL47877A (en) * 1974-08-26 1978-10-31 Sparamedica Ag Thienothiazine carboxamide derivatives,their manufacture and pharmaceutical compositions containing them
CA1066711A (en) * 1974-08-26 1979-11-20 Hoffmann-La Roche Limited Thiophene derivatives
AU518216B2 (en) * 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives

Also Published As

Publication number Publication date
DK155009B (da) 1989-01-23
DE3371082D1 (de) 1987-05-27
PH19692A (en) 1986-06-13
IE55942B1 (en) 1991-02-27
IL69628A0 (en) 1983-12-30
ATE26720T1 (de) 1987-05-15
US4544655A (en) 1985-10-01
DK381283D0 (da) 1983-08-19
EP0103142B1 (de) 1987-04-22
DK155009C (da) 1989-06-05
AU1900783A (en) 1984-03-15
CA1217187A (en) 1987-01-27
JPS5967292A (ja) 1984-04-16
IE832108L (en) 1984-03-09
EP0103142A1 (de) 1984-03-21
NZ205475A (en) 1985-08-30
DK381283A (da) 1984-03-10
ZA836546B (en) 1984-04-25
AU560973B2 (en) 1987-04-30

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