IL68422A0 - Hydantoin derivatives and their use in medicine - Google Patents
Hydantoin derivatives and their use in medicineInfo
- Publication number
- IL68422A0 IL68422A0 IL68422A IL6842283A IL68422A0 IL 68422 A0 IL68422 A0 IL 68422A0 IL 68422 A IL68422 A IL 68422A IL 6842283 A IL6842283 A IL 6842283A IL 68422 A0 IL68422 A0 IL 68422A0
- Authority
- IL
- Israel
- Prior art keywords
- medicine
- hydantoin derivatives
- chromanimidazolidine
- methythio
- methylsulfinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/368,629 US4464385A (en) | 1982-04-15 | 1982-04-15 | Treatment of diabetic complications with hydantoins |
Publications (1)
Publication Number | Publication Date |
---|---|
IL68422A0 true IL68422A0 (en) | 1983-07-31 |
Family
ID=23452055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL68422A IL68422A0 (en) | 1982-04-15 | 1983-04-15 | Hydantoin derivatives and their use in medicine |
Country Status (15)
Country | Link |
---|---|
US (1) | US4464385A (es) |
EP (1) | EP0092386B1 (es) |
KR (1) | KR890000156B1 (es) |
AT (1) | ATE36333T1 (es) |
AU (1) | AU552937B2 (es) |
CA (1) | CA1201715A (es) |
DE (1) | DE3377650D1 (es) |
ES (3) | ES8500951A1 (es) |
GR (1) | GR78183B (es) |
IE (1) | IE55227B1 (es) |
IL (1) | IL68422A0 (es) |
NZ (1) | NZ203875A (es) |
PT (1) | PT76551B (es) |
WO (1) | WO1983003542A1 (es) |
ZA (1) | ZA832491B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4540700A (en) * | 1982-04-15 | 1985-09-10 | Alcon Laboratories, Inc. | Treatment of diabetic complications with certain spiro-imidazolidine-diones |
JPH0772190B2 (ja) * | 1985-02-26 | 1995-08-02 | エーザイ株式会社 | ヒダントイン誘導体 |
JPS61200991A (ja) * | 1985-03-04 | 1986-09-05 | Sanwa Kagaku Kenkyusho:Kk | スピロ―3―ヘテロアゾリジン化合物、その製法及びそれを有効成分とする糖尿病合併症の予防及び治療剤 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2716648A (en) * | 1955-08-30 | Hydantoin derivatives | ||
US2683718A (en) * | 1952-01-11 | 1954-07-13 | Searle & Co | Spiro-[xanthene-9, 4'-imidazolidine]-2, 5-dione |
US3349124A (en) * | 1957-05-20 | 1967-10-24 | Pfizer & Co C | Oral antidiabetic agent |
DE1135915B (de) * | 1961-06-29 | 1962-09-06 | Asta Werke Ag Chem Fab | Verfahren zur Herstellung neuer, antikonvulsiv wirksamer Spirohydantoine |
US3532744A (en) * | 1967-07-28 | 1970-10-06 | American Home Prod | 1- and 2-amino substituted indane and tetralene carboxylic acids |
US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
US4117230A (en) * | 1976-10-18 | 1978-09-26 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
US4209630A (en) * | 1976-10-18 | 1980-06-24 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
US4147795A (en) * | 1977-02-11 | 1979-04-03 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
US4127665A (en) * | 1978-01-18 | 1978-11-28 | Pfizer Inc. | Thienohydantoin derivatives |
US4147797A (en) * | 1978-08-11 | 1979-04-03 | Pfizer Inc. | Spiro-furanohydantoin derivatives |
US4200642A (en) * | 1978-08-21 | 1980-04-29 | Pfizer Inc. | Spiro-oxazolidindiones |
US4181728A (en) * | 1978-11-16 | 1980-01-01 | Pfizer Inc. | Spiro-polycyclicimidazolidinedione derivatives |
US4327107A (en) * | 1979-02-06 | 1982-04-27 | A. H. Robins Company, Inc. | Method useful in the treatment of sugar cataracts using 4-substituted-2-iminoimidazolidine compounds |
US4181729A (en) * | 1979-03-21 | 1980-01-01 | Pfizer Inc. | Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives |
US4307108A (en) * | 1979-12-26 | 1981-12-22 | Pfizer Inc. | Method for lowering sorbitol levels using spiro-imides |
JPS5899480A (ja) * | 1981-12-04 | 1983-06-13 | Senjiyu Seiyaku Kk | 新規クロマン誘導体 |
-
1982
- 1982-04-15 US US06/368,629 patent/US4464385A/en not_active Expired - Fee Related
-
1983
- 1983-04-08 AU AU13258/83A patent/AU552937B2/en not_active Ceased
- 1983-04-08 ZA ZA832491A patent/ZA832491B/xx unknown
- 1983-04-11 WO PCT/US1983/000545 patent/WO1983003542A1/en unknown
- 1983-04-12 IE IE836/83A patent/IE55227B1/en not_active IP Right Cessation
- 1983-04-13 NZ NZ203875A patent/NZ203875A/en unknown
- 1983-04-13 GR GR71073A patent/GR78183B/el unknown
- 1983-04-14 AT AT83302112T patent/ATE36333T1/de not_active IP Right Cessation
- 1983-04-14 KR KR8301570A patent/KR890000156B1/ko not_active IP Right Cessation
- 1983-04-14 EP EP83302112A patent/EP0092386B1/en not_active Expired
- 1983-04-14 PT PT76551A patent/PT76551B/pt not_active IP Right Cessation
- 1983-04-14 ES ES521445A patent/ES8500951A1/es not_active Expired
- 1983-04-14 CA CA000425865A patent/CA1201715A/en not_active Expired
- 1983-04-14 DE DE8383302112T patent/DE3377650D1/de not_active Expired
- 1983-04-15 IL IL68422A patent/IL68422A0/xx not_active IP Right Cessation
-
1984
- 1984-11-30 ES ES538138A patent/ES8507552A1/es not_active Expired
- 1984-11-30 ES ES538137A patent/ES8602799A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
PT76551B (en) | 1986-01-21 |
EP0092386A2 (en) | 1983-10-26 |
ES538138A0 (es) | 1985-09-01 |
US4464385A (en) | 1984-08-07 |
WO1983003542A1 (en) | 1983-10-27 |
ES521445A0 (es) | 1984-11-01 |
CA1201715A (en) | 1986-03-11 |
AU1325883A (en) | 1983-10-20 |
DE3377650D1 (en) | 1988-09-15 |
ZA832491B (en) | 1983-12-28 |
AU552937B2 (en) | 1986-06-26 |
ATE36333T1 (de) | 1988-08-15 |
EP0092386A3 (en) | 1985-03-06 |
IE55227B1 (en) | 1990-07-04 |
NZ203875A (en) | 1985-12-13 |
ES538137A0 (es) | 1985-12-01 |
GR78183B (es) | 1984-09-26 |
EP0092386B1 (en) | 1988-08-10 |
IE830836L (en) | 1983-10-15 |
ES8602799A1 (es) | 1985-12-01 |
ES8507552A1 (es) | 1985-09-01 |
KR890000156B1 (en) | 1989-03-08 |
PT76551A (en) | 1983-05-01 |
ES8500951A1 (es) | 1984-11-01 |
KR840004431A (ko) | 1984-10-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void |