ZA832491B - Hydantoin therapeutic agents - Google Patents
Hydantoin therapeutic agentsInfo
- Publication number
- ZA832491B ZA832491B ZA832491A ZA832491A ZA832491B ZA 832491 B ZA832491 B ZA 832491B ZA 832491 A ZA832491 A ZA 832491A ZA 832491 A ZA832491 A ZA 832491A ZA 832491 B ZA832491 B ZA 832491B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydantoin
- therapeutic agents
- chromanimidazolidine
- methythio
- methylsulfinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/368,629 US4464385A (en) | 1982-04-15 | 1982-04-15 | Treatment of diabetic complications with hydantoins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA832491B true ZA832491B (en) | 1983-12-28 |
Family
ID=23452055
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA832491A ZA832491B (en) | 1982-04-15 | 1983-04-08 | Hydantoin therapeutic agents |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4464385A (xx) |
| EP (1) | EP0092386B1 (xx) |
| KR (1) | KR890000156B1 (xx) |
| AT (1) | ATE36333T1 (xx) |
| AU (1) | AU552937B2 (xx) |
| CA (1) | CA1201715A (xx) |
| DE (1) | DE3377650D1 (xx) |
| ES (3) | ES521445A0 (xx) |
| GR (1) | GR78183B (xx) |
| IE (1) | IE55227B1 (xx) |
| IL (1) | IL68422A0 (xx) |
| NZ (1) | NZ203875A (xx) |
| PT (1) | PT76551B (xx) |
| WO (1) | WO1983003542A1 (xx) |
| ZA (1) | ZA832491B (xx) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4540700A (en) * | 1982-04-15 | 1985-09-10 | Alcon Laboratories, Inc. | Treatment of diabetic complications with certain spiro-imidazolidine-diones |
| JPH0772190B2 (ja) * | 1985-02-26 | 1995-08-02 | エーザイ株式会社 | ヒダントイン誘導体 |
| JPS61200991A (ja) * | 1985-03-04 | 1986-09-05 | Sanwa Kagaku Kenkyusho:Kk | スピロ―３―ヘテロアゾリジン化合物、その製法及びそれを有効成分とする糖尿病合併症の予防及び治療剤 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2716648A (en) * | 1955-08-30 | Hydantoin derivatives | ||
| US2683718A (en) * | 1952-01-11 | 1954-07-13 | Searle & Co | Spiro-[xanthene-9, 4'-imidazolidine]-2, 5-dione |
| US3349124A (en) * | 1957-05-20 | 1967-10-24 | Pfizer & Co C | Oral antidiabetic agent |
| DE1135915B (de) * | 1961-06-29 | 1962-09-06 | Asta Werke Ag Chem Fab | Verfahren zur Herstellung neuer, antikonvulsiv wirksamer Spirohydantoine |
| US3532744A (en) * | 1967-07-28 | 1970-10-06 | American Home Prod | 1- and 2-amino substituted indane and tetralene carboxylic acids |
| US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
| US4117230A (en) * | 1976-10-18 | 1978-09-26 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4209630A (en) * | 1976-10-18 | 1980-06-24 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4147795A (en) * | 1977-02-11 | 1979-04-03 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
| US4127665A (en) * | 1978-01-18 | 1978-11-28 | Pfizer Inc. | Thienohydantoin derivatives |
| US4147797A (en) * | 1978-08-11 | 1979-04-03 | Pfizer Inc. | Spiro-furanohydantoin derivatives |
| US4200642A (en) * | 1978-08-21 | 1980-04-29 | Pfizer Inc. | Spiro-oxazolidindiones |
| US4181728A (en) * | 1978-11-16 | 1980-01-01 | Pfizer Inc. | Spiro-polycyclicimidazolidinedione derivatives |
| US4327107A (en) * | 1979-02-06 | 1982-04-27 | A. H. Robins Company, Inc. | Method useful in the treatment of sugar cataracts using 4-substituted-2-iminoimidazolidine compounds |
| US4181729A (en) * | 1979-03-21 | 1980-01-01 | Pfizer Inc. | Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives |
| US4307108A (en) * | 1979-12-26 | 1981-12-22 | Pfizer Inc. | Method for lowering sorbitol levels using spiro-imides |
| JPS5899480A (ja) * | 1981-12-04 | 1983-06-13 | Senjiyu Seiyaku Kk | 新規クロマン誘導体 |
-
1982
- 1982-04-15 US US06/368,629 patent/US4464385A/en not_active Expired - Fee Related
-
1983
- 1983-04-08 ZA ZA832491A patent/ZA832491B/xx unknown
- 1983-04-08 AU AU13258/83A patent/AU552937B2/en not_active Ceased
- 1983-04-11 WO PCT/US1983/000545 patent/WO1983003542A1/en unknown
- 1983-04-12 IE IE836/83A patent/IE55227B1/en not_active IP Right Cessation
- 1983-04-13 NZ NZ203875A patent/NZ203875A/en unknown
- 1983-04-13 GR GR71073A patent/GR78183B/el unknown
- 1983-04-14 ES ES521445A patent/ES521445A0/es active Granted
- 1983-04-14 PT PT76551A patent/PT76551B/pt not_active IP Right Cessation
- 1983-04-14 AT AT83302112T patent/ATE36333T1/de not_active IP Right Cessation
- 1983-04-14 DE DE8383302112T patent/DE3377650D1/de not_active Expired
- 1983-04-14 EP EP83302112A patent/EP0092386B1/en not_active Expired
- 1983-04-14 CA CA000425865A patent/CA1201715A/en not_active Expired
- 1983-04-14 KR KR8301570A patent/KR890000156B1/ko not_active IP Right Cessation
- 1983-04-15 IL IL68422A patent/IL68422A0/xx not_active IP Right Cessation
-
1984
- 1984-11-30 ES ES538138A patent/ES538138A0/es active Granted
- 1984-11-30 ES ES538137A patent/ES538137A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES8602799A1 (es) | 1985-12-01 |
| EP0092386B1 (en) | 1988-08-10 |
| US4464385A (en) | 1984-08-07 |
| ATE36333T1 (de) | 1988-08-15 |
| AU552937B2 (en) | 1986-06-26 |
| EP0092386A2 (en) | 1983-10-26 |
| ES8500951A1 (es) | 1984-11-01 |
| ES8507552A1 (es) | 1985-09-01 |
| AU1325883A (en) | 1983-10-20 |
| WO1983003542A1 (en) | 1983-10-27 |
| CA1201715A (en) | 1986-03-11 |
| KR890000156B1 (en) | 1989-03-08 |
| PT76551B (en) | 1986-01-21 |
| PT76551A (en) | 1983-05-01 |
| NZ203875A (en) | 1985-12-13 |
| GR78183B (xx) | 1984-09-26 |
| DE3377650D1 (en) | 1988-09-15 |
| ES521445A0 (es) | 1984-11-01 |
| ES538137A0 (es) | 1985-12-01 |
| IE55227B1 (en) | 1990-07-04 |
| IL68422A0 (en) | 1983-07-31 |
| IE830836L (en) | 1983-10-15 |
| EP0092386A3 (en) | 1985-03-06 |
| ES538138A0 (es) | 1985-09-01 |
| KR840004431A (ko) | 1984-10-15 |
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