IL67011A - 2'-substituted-spiro(benzofuran-2(3h),1'-cycloalkanes),process for preparing them and pharmaceutical compositions containing them - Google Patents

2'-substituted-spiro(benzofuran-2(3h),1'-cycloalkanes),process for preparing them and pharmaceutical compositions containing them

Info

Publication number
IL67011A
IL67011A IL67011A IL6701182A IL67011A IL 67011 A IL67011 A IL 67011A IL 67011 A IL67011 A IL 67011A IL 6701182 A IL6701182 A IL 6701182A IL 67011 A IL67011 A IL 67011A
Authority
IL
Israel
Prior art keywords
cycloalkanes
benzofuran
spiro
substituted
preparing
Prior art date
Application number
IL67011A
Other languages
English (en)
Other versions
IL67011A0 (en
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/313,097 external-priority patent/US4404221A/en
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of IL67011A0 publication Critical patent/IL67011A0/xx
Publication of IL67011A publication Critical patent/IL67011A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL67011A 1981-10-19 1982-10-18 2'-substituted-spiro(benzofuran-2(3h),1'-cycloalkanes),process for preparing them and pharmaceutical compositions containing them IL67011A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/313,097 US4404221A (en) 1981-10-19 1981-10-19 2'-Substituted-spiro[benzofuran-2(3H),1'-cyclohexanes] and its pharmaceutical use
US06/416,446 US4517311A (en) 1981-10-19 1982-09-13 2'-Substituted-spiro[benzofuran-2(3H),1'-cycloalkanes] and their analgesic and anti-depressant compositions

Publications (2)

Publication Number Publication Date
IL67011A0 IL67011A0 (en) 1983-02-23
IL67011A true IL67011A (en) 1988-07-31

Family

ID=26978681

Family Applications (1)

Application Number Title Priority Date Filing Date
IL67011A IL67011A (en) 1981-10-19 1982-10-18 2'-substituted-spiro(benzofuran-2(3h),1'-cycloalkanes),process for preparing them and pharmaceutical compositions containing them

Country Status (7)

Country Link
US (1) US4517311A (es)
EP (1) EP0077536B1 (es)
KR (1) KR880001814B1 (es)
AU (1) AU564232B2 (es)
DE (1) DE3272035D1 (es)
ES (3) ES516610A0 (es)
IL (1) IL67011A (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4910323A (en) * 1981-10-19 1990-03-20 Hoechst Roussel Pharmaceuticals, Inc. 2'-substituted-spiro(benzofuran-2(3H),1'-cyclohexanes) and intermediates thereof
US4623657A (en) 1985-09-05 1986-11-18 Hoechst-Roussel Pharmaceuticals Inc. Spiro [benzofuran-2(3H),1'-cycloheptane]s and their therapeutic use
US5366986A (en) * 1988-04-15 1994-11-22 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity
US5506247A (en) * 1988-04-15 1996-04-09 T Cell Sciences, Inc. Compounds that inhibit complement and/or suppress immune activity
US5173499A (en) * 1988-04-15 1992-12-22 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity
US4906655A (en) * 1989-01-24 1990-03-06 Warner-Lambert Company Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB913535A (en) * 1960-05-16 1962-12-19 Ici Ltd Coumaran derivatives
SE7308238L (es) * 1973-06-15 1974-12-13 Sandoz Ag
US3959475A (en) * 1973-12-12 1976-05-25 American Hoechst Corporation Substituted 1,3-dihydrospiro(isobenzofuran)s
US4166120A (en) * 1978-04-14 1979-08-28 American Hoechst Corporation Analgesic and tranquilizing benzoylpropyl-spiro[dihydrobenzofuran]piperidines and pyrrolidines
US4166119A (en) * 1978-04-14 1979-08-28 American Hoechst Corporation Analgesic and tranquilizing spiro[dihydrobenzofuran]piperidines and pyrrolidines
US4263317A (en) * 1979-09-06 1981-04-21 Hoechst-Roussel Pharmaceuticals, Inc. Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s
US4404221A (en) * 1981-10-19 1983-09-13 Hoechst-Roussel Pharmaceuticals Inc. 2'-Substituted-spiro[benzofuran-2(3H),1'-cyclohexanes] and its pharmaceutical use

Also Published As

Publication number Publication date
ES8506688A1 (es) 1985-07-16
AU8944082A (en) 1983-04-28
IL67011A0 (en) 1983-02-23
AU564232B2 (en) 1987-08-06
ES8404341A1 (es) 1984-04-16
EP0077536B1 (en) 1986-07-16
DE3272035D1 (en) 1986-08-21
EP0077536A3 (en) 1983-08-03
ES8507531A1 (es) 1985-09-01
ES516610A0 (es) 1984-04-16
ES529362A0 (es) 1985-07-16
US4517311A (en) 1985-05-14
ES529361A0 (es) 1985-09-01
EP0077536A2 (en) 1983-04-27
KR840001967A (ko) 1984-06-07
KR880001814B1 (ko) 1988-09-19

Similar Documents

Publication Publication Date Title
IL70311A (en) 4-aminoalkyl-2(3h)-indolones,process for their preparation and pharmaceutical compositions containing them
DE3263633D1 (en) Imidazodiazepines, process for their preparation and pharmaceutical compositions containing them
PT74923B (en) Process for preparing 1,2-diaminocyclobutene-3,4-di ones substituted and pharmaceutical compositions therewith
ZA859756B (en) Peptide-aldehydes,process for the preparation thereof and pharmaceutical compositions containing the same
DE3275296D1 (en) Azabicyclo-(3,3,1)-nonylbenzamide derivatives, processes for their preparation, and pharmaceutical compositions containing them
DE3270202D1 (en) 3,5-di-tert-butylstyrene derivatives, processes for their preparations, and pharmaceutical compositions containing them
HUT46303A (en) Process for producing 3-/omega-/3,5-di-/tetrabutil/-4-hydroxy-phenyl/-alkanoyl/-pyrroles andtheyr deoxy-analogues and pharmaceutical compositions containing them
DE3277838D1 (en) Thiazolylurea derivatives, process for their preparation, and medicinal composition containing same
IL68680A (en) 2,3,4-trinor-1,5-inter-m-phenylene-prostacyclin-i2-analogues,process for their preparation and pharmaceutical compositions containing them
DE3271383D1 (en) Ascochlorin derivatives; process for preparing the same and pharmaceutical composition containing the same
IL67011A (en) 2'-substituted-spiro(benzofuran-2(3h),1'-cycloalkanes),process for preparing them and pharmaceutical compositions containing them
HUT37423A (en) Process for preparing 1,3-dioxolanyl derivatives and pharmaceutical compositions containing thereof
IL62800A0 (en) Substituted 2(3h)-benzothiazolone derivatives,their preparation and pharmaceutical compositions containing them
ZA827595B (en) 2'-substituted-spiro(benzofuran-2(3h),1'-cycloalkanes)and intermediates thereof,a process for preparing same,pharmaceutical compositions containing such compounds and their use as medicaments
DE2964803D1 (en) 2-azaergolines and 2-aza-8(or 9)-ergolenes, process for their preparation and pharmaceutical compositions containing them
PT74400B (en) Process for the preparation of 17,18-dehydro-apovincaminol-3', 4',5'-trimethoxy-benzoate and of pharmaceutical compositions containing them
IL65368A0 (en) Mercapto acyl-carnitines,process for their preparation and pharmaceutical compositions containing same
HUT45261A (en) Process for producing 7-oxo-4-thia-1-aza-bicyclo/3.2.0/-hept-2-ene derivatives and pharmaceutical compositions containing them
GB2109377B (en) Uracil derivatives, process for their preparation, and medicinal composition containing same
HUT40427A (en) Process for producing 1,3,4-oxa- and -thia-diazol derivatives and pharmaceutical compositions containing them
ZA826528B (en) Ascochlorin derivatives,process for preparing the same and pharmaceutical composition containing the same
IL71432A (en) 3(2-furoyl)-4,7-dihydropyridine derivatives,process for their preparation and pharmaceutical compositions containing them
DE3271206D1 (en) Inter-m-phenylene-pgi2 derivatives, process for their preparation and pharmaceutical compositions containing them
IL64641A0 (en) 2(3h)-indolones,process for their preparation and compositions containing them
DE3166701D1 (en) 3-amino-5-substituted-6-halo-n-(3,4-dihydro- or 4,4-disubstituted-6-substituted-1,3,5-triazin-2-yl)-2-pyrazinecarboxamides, process for preparing and pharmaceutical compositions containing the same