IL66954A - Spiro(3h'-indoline-3,5'-oxazolidine)-2,2',4'(1h)-trione derivatives and pharmaceutical compositions containing them - Google Patents
Spiro(3h'-indoline-3,5'-oxazolidine)-2,2',4'(1h)-trione derivatives and pharmaceutical compositions containing themInfo
- Publication number
- IL66954A IL66954A IL66954A IL6695482A IL66954A IL 66954 A IL66954 A IL 66954A IL 66954 A IL66954 A IL 66954A IL 6695482 A IL6695482 A IL 6695482A IL 66954 A IL66954 A IL 66954A
- Authority
- IL
- Israel
- Prior art keywords
- oxazolidine
- indoline
- spiro
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31068281A | 1981-10-13 | 1981-10-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL66954A0 IL66954A0 (en) | 1983-02-23 |
IL66954A true IL66954A (en) | 1985-02-28 |
Family
ID=23203647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL66954A IL66954A (en) | 1981-10-13 | 1982-10-11 | Spiro(3h'-indoline-3,5'-oxazolidine)-2,2',4'(1h)-trione derivatives and pharmaceutical compositions containing them |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0079675A1 (es) |
JP (1) | JPS5877883A (es) |
KR (1) | KR860000486B1 (es) |
AR (1) | AR231839A1 (es) |
AU (1) | AU531161B2 (es) |
CA (1) | CA1171860A (es) |
DK (1) | DK449882A (es) |
ES (1) | ES515751A0 (es) |
FI (1) | FI823480L (es) |
GR (1) | GR77019B (es) |
HU (1) | HU185113B (es) |
IL (1) | IL66954A (es) |
PH (1) | PH18038A (es) |
PL (1) | PL238595A1 (es) |
PT (1) | PT75673B (es) |
YU (1) | YU229382A (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA832679B (en) * | 1982-05-07 | 1983-12-28 | Ici Plc | Indoline derivatives |
DE3561198D1 (en) * | 1984-03-23 | 1988-01-28 | Pfizer | Spiro-indenes and spiro-1,2-dihydro-naphthalenes for treatment of diabetic complications |
US4968707A (en) * | 1987-06-10 | 1990-11-06 | Pfizer Inc. | Oxazolidin-2-one derivatives as hypoglycemic agents |
AU617541B2 (en) * | 1988-10-20 | 1991-11-28 | Wyeth | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors |
US5221686A (en) * | 1992-08-04 | 1993-06-22 | American Home Products Corporation | Spiro[1,2-benzisothiazole-3(2H),5'-oxazolidine]-2',4'-dione 1,1-dioxides as antihyperglycemic agents |
FR2708606B1 (fr) * | 1993-07-30 | 1995-10-27 | Sanofi Sa | Dérivés du N-phénylalkylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant. |
CN102336769A (zh) * | 2011-07-06 | 2012-02-01 | 华东理工大学 | 一种简便的合成螺[氧化吲哚-3,5'-噁唑啉]杂环化合物的新方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4200642A (en) * | 1978-08-21 | 1980-04-29 | Pfizer Inc. | Spiro-oxazolidindiones |
-
1982
- 1982-09-16 ES ES515751A patent/ES515751A0/es active Granted
- 1982-10-08 EP EP82305385A patent/EP0079675A1/en not_active Withdrawn
- 1982-10-11 YU YU02293/82A patent/YU229382A/xx unknown
- 1982-10-11 KR KR8204569A patent/KR860000486B1/ko active
- 1982-10-11 GR GR69495A patent/GR77019B/el unknown
- 1982-10-11 AR AR290934A patent/AR231839A1/es active
- 1982-10-11 IL IL66954A patent/IL66954A/xx unknown
- 1982-10-12 HU HU823246A patent/HU185113B/hu unknown
- 1982-10-12 PH PH27974A patent/PH18038A/en unknown
- 1982-10-12 PT PT75673A patent/PT75673B/pt unknown
- 1982-10-12 FI FI823480A patent/FI823480L/fi not_active Application Discontinuation
- 1982-10-12 DK DK449882A patent/DK449882A/da not_active Application Discontinuation
- 1982-10-12 PL PL23859582A patent/PL238595A1/xx unknown
- 1982-10-12 AU AU89288/82A patent/AU531161B2/en not_active Ceased
- 1982-10-12 CA CA000413239A patent/CA1171860A/en not_active Expired
- 1982-10-13 JP JP57179684A patent/JPS5877883A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
AU8928882A (en) | 1983-04-21 |
GR77019B (es) | 1984-09-04 |
PL238595A1 (en) | 1983-09-12 |
ES8400116A1 (es) | 1983-10-16 |
PT75673B (en) | 1985-12-09 |
YU229382A (en) | 1984-12-31 |
KR860000486B1 (ko) | 1986-04-30 |
FI823480L (fi) | 1983-04-14 |
KR840002002A (ko) | 1984-06-11 |
PH18038A (en) | 1985-03-08 |
CA1171860A (en) | 1984-07-31 |
JPS611073B2 (es) | 1986-01-13 |
FI823480A0 (fi) | 1982-10-12 |
HU185113B (en) | 1984-12-28 |
AR231839A1 (es) | 1985-03-29 |
PT75673A (en) | 1982-11-01 |
JPS5877883A (ja) | 1983-05-11 |
IL66954A0 (en) | 1983-02-23 |
DK449882A (da) | 1983-04-14 |
ES515751A0 (es) | 1983-10-16 |
EP0079675A1 (en) | 1983-05-25 |
AU531161B2 (en) | 1983-08-11 |
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