IL66954A - Spiro(3h'-indoline-3,5'-oxazolidine)-2,2',4'(1h)-trione derivatives and pharmaceutical compositions containing them - Google Patents

Spiro(3h'-indoline-3,5'-oxazolidine)-2,2',4'(1h)-trione derivatives and pharmaceutical compositions containing them

Info

Publication number
IL66954A
IL66954A IL66954A IL6695482A IL66954A IL 66954 A IL66954 A IL 66954A IL 66954 A IL66954 A IL 66954A IL 6695482 A IL6695482 A IL 6695482A IL 66954 A IL66954 A IL 66954A
Authority
IL
Israel
Prior art keywords
oxazolidine
indoline
spiro
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL66954A
Other languages
English (en)
Other versions
IL66954A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL66954A0 publication Critical patent/IL66954A0/xx
Publication of IL66954A publication Critical patent/IL66954A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/38Oxygen atoms in positions 2 and 3, e.g. isatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL66954A 1981-10-13 1982-10-11 Spiro(3h'-indoline-3,5'-oxazolidine)-2,2',4'(1h)-trione derivatives and pharmaceutical compositions containing them IL66954A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31068281A 1981-10-13 1981-10-13

Publications (2)

Publication Number Publication Date
IL66954A0 IL66954A0 (en) 1983-02-23
IL66954A true IL66954A (en) 1985-02-28

Family

ID=23203647

Family Applications (1)

Application Number Title Priority Date Filing Date
IL66954A IL66954A (en) 1981-10-13 1982-10-11 Spiro(3h'-indoline-3,5'-oxazolidine)-2,2',4'(1h)-trione derivatives and pharmaceutical compositions containing them

Country Status (16)

Country Link
EP (1) EP0079675A1 (es)
JP (1) JPS5877883A (es)
KR (1) KR860000486B1 (es)
AR (1) AR231839A1 (es)
AU (1) AU531161B2 (es)
CA (1) CA1171860A (es)
DK (1) DK449882A (es)
ES (1) ES515751A0 (es)
FI (1) FI823480L (es)
GR (1) GR77019B (es)
HU (1) HU185113B (es)
IL (1) IL66954A (es)
PH (1) PH18038A (es)
PL (1) PL238595A1 (es)
PT (1) PT75673B (es)
YU (1) YU229382A (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA832679B (en) * 1982-05-07 1983-12-28 Ici Plc Indoline derivatives
DE3561198D1 (en) * 1984-03-23 1988-01-28 Pfizer Spiro-indenes and spiro-1,2-dihydro-naphthalenes for treatment of diabetic complications
US4968707A (en) * 1987-06-10 1990-11-06 Pfizer Inc. Oxazolidin-2-one derivatives as hypoglycemic agents
AU617541B2 (en) * 1988-10-20 1991-11-28 Wyeth Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors
US5221686A (en) * 1992-08-04 1993-06-22 American Home Products Corporation Spiro[1,2-benzisothiazole-3(2H),5'-oxazolidine]-2',4'-dione 1,1-dioxides as antihyperglycemic agents
FR2708606B1 (fr) * 1993-07-30 1995-10-27 Sanofi Sa Dérivés du N-phénylalkylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant.
CN102336769A (zh) * 2011-07-06 2012-02-01 华东理工大学 一种简便的合成螺[氧化吲哚-3,5'-噁唑啉]杂环化合物的新方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200642A (en) * 1978-08-21 1980-04-29 Pfizer Inc. Spiro-oxazolidindiones

Also Published As

Publication number Publication date
AU8928882A (en) 1983-04-21
GR77019B (es) 1984-09-04
PL238595A1 (en) 1983-09-12
ES8400116A1 (es) 1983-10-16
PT75673B (en) 1985-12-09
YU229382A (en) 1984-12-31
KR860000486B1 (ko) 1986-04-30
FI823480L (fi) 1983-04-14
KR840002002A (ko) 1984-06-11
PH18038A (en) 1985-03-08
CA1171860A (en) 1984-07-31
JPS611073B2 (es) 1986-01-13
FI823480A0 (fi) 1982-10-12
HU185113B (en) 1984-12-28
AR231839A1 (es) 1985-03-29
PT75673A (en) 1982-11-01
JPS5877883A (ja) 1983-05-11
IL66954A0 (en) 1983-02-23
DK449882A (da) 1983-04-14
ES515751A0 (es) 1983-10-16
EP0079675A1 (en) 1983-05-25
AU531161B2 (en) 1983-08-11

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