IL64755A - 1-(2-(4,5,10,11-tetrahydro-1h-dibenzo(a,d)cyclohepten-5-yl)-ethyl)pyrrolidine and pharmaceutically acceptable acid addition salts thereof,their preparation and pharmaceutical compositions containing them - Google Patents

1-(2-(4,5,10,11-tetrahydro-1h-dibenzo(a,d)cyclohepten-5-yl)-ethyl)pyrrolidine and pharmaceutically acceptable acid addition salts thereof,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL64755A
IL64755A IL64755A IL6475582A IL64755A IL 64755 A IL64755 A IL 64755A IL 64755 A IL64755 A IL 64755A IL 6475582 A IL6475582 A IL 6475582A IL 64755 A IL64755 A IL 64755A
Authority
IL
Israel
Prior art keywords
cyclohepten
dibenzo
pyrrolidine
tetrahydro
ethyl
Prior art date
Application number
IL64755A
Other languages
English (en)
Other versions
IL64755A0 (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL64755A0 publication Critical patent/IL64755A0/xx
Publication of IL64755A publication Critical patent/IL64755A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
    • C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL64755A 1981-01-16 1982-01-11 1-(2-(4,5,10,11-tetrahydro-1h-dibenzo(a,d)cyclohepten-5-yl)-ethyl)pyrrolidine and pharmaceutically acceptable acid addition salts thereof,their preparation and pharmaceutical compositions containing them IL64755A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH27381 1981-01-16

Publications (2)

Publication Number Publication Date
IL64755A0 IL64755A0 (en) 1982-03-31
IL64755A true IL64755A (en) 1985-04-30

Family

ID=4183246

Family Applications (1)

Application Number Title Priority Date Filing Date
IL64755A IL64755A (en) 1981-01-16 1982-01-11 1-(2-(4,5,10,11-tetrahydro-1h-dibenzo(a,d)cyclohepten-5-yl)-ethyl)pyrrolidine and pharmaceutically acceptable acid addition salts thereof,their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (2) US4513002A (fr)
EP (1) EP0056617B1 (fr)
JP (1) JPS57139021A (fr)
KR (1) KR880001863B1 (fr)
AR (1) AR229877A1 (fr)
AT (1) ATE16484T1 (fr)
AU (1) AU550523B2 (fr)
CA (1) CA1157853A (fr)
DE (1) DE3267334D1 (fr)
DK (1) DK17982A (fr)
ES (2) ES508775A0 (fr)
FI (1) FI76572C (fr)
GR (1) GR75161B (fr)
HU (1) HU184981B (fr)
IE (1) IE51955B1 (fr)
IL (1) IL64755A (fr)
MC (1) MC1439A1 (fr)
NO (1) NO157374C (fr)
NZ (1) NZ199451A (fr)
PH (1) PH17091A (fr)
PT (1) PT74287A (fr)
YU (1) YU6782A (fr)
ZA (1) ZA82136B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513002A (en) * 1981-01-16 1985-04-23 Hoffmann-La Roche Inc. Cycloheptene derivatives
US5049673A (en) * 1987-10-30 1991-09-17 The Regents Of The University Of California Fluorescent indicator dyes for calcium working at long wavelengths
US4920025A (en) * 1988-04-08 1990-04-24 Xerox Corporation Control of selenium alloy fractionation
US5223409A (en) * 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP2218442A1 (fr) 2005-11-09 2010-08-18 CombinatoRx, Inc. Procédés, compositions et kits pour le traitement des maladies ophthalmiques

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3409640A (en) * 1959-07-22 1968-11-05 Schering Corp 5-(3'-dimethylamino-2'-methyl-propyl)dibenzocycloheptenes
GB1017696A (en) * 1961-09-25 1966-01-19 Merck & Co Inc Substituted 5h-dibenzo[a, d]cycloheptenes and 10,11-dihydro-5h-dibenzo[a, d]cycloheptenes
US3922305A (en) * 1962-08-09 1975-11-25 Merck & Co Inc Chemical compounds
US4136116A (en) * 1968-05-03 1979-01-23 Hoffmann-La Roche Inc. Tricyclic compounds
US4127717A (en) * 1978-03-20 1978-11-28 E. R. Squibb & Sons, Inc. Benzo-cyclitolamines
US4513002A (en) * 1981-01-16 1985-04-23 Hoffmann-La Roche Inc. Cycloheptene derivatives
US4337260A (en) * 1981-09-10 1982-06-29 Yoshitomi Pharmaceutical Industries, Ltd. Imidazopyridine-spiro-piperidine compounds

Also Published As

Publication number Publication date
ES517501A0 (es) 1984-01-01
EP0056617A3 (en) 1982-11-17
AU7941882A (en) 1982-07-22
US4513002A (en) 1985-04-23
ES8304557A1 (es) 1983-03-16
NO157374B (no) 1987-11-30
FI76572C (fi) 1988-11-10
AR229877A1 (es) 1983-12-30
PT74287A (en) 1982-02-01
IE51955B1 (en) 1987-04-29
YU6782A (en) 1985-03-20
JPS57139021A (en) 1982-08-27
IL64755A0 (en) 1982-03-31
NZ199451A (en) 1984-12-14
ES8401760A1 (es) 1984-01-01
GR75161B (fr) 1984-07-13
ES508775A0 (es) 1983-03-16
CA1157853A (fr) 1983-11-29
ZA82136B (en) 1982-11-24
KR830009021A (ko) 1983-12-17
EP0056617A2 (fr) 1982-07-28
FI76572B (fi) 1988-07-29
IE820072L (en) 1982-07-16
AU550523B2 (en) 1986-03-27
NO157374C (no) 1988-03-09
HU184981B (en) 1984-11-28
DK17982A (da) 1982-07-17
EP0056617B1 (fr) 1985-11-13
KR880001863B1 (ko) 1988-09-23
US4691040A (en) 1987-09-01
NO820125L (no) 1982-07-19
MC1439A1 (fr) 1982-12-06
ATE16484T1 (de) 1985-11-15
DE3267334D1 (en) 1985-12-19
FI820106L (fi) 1982-07-17
PH17091A (en) 1984-05-29

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