IL64332A0 - Compounds of dichlorodiethylamino-phenylalanine with anti-cancer tumor activity - Google Patents

Compounds of dichlorodiethylamino-phenylalanine with anti-cancer tumor activity

Info

Publication number
IL64332A0
IL64332A0 IL64332A IL6433281A IL64332A0 IL 64332 A0 IL64332 A0 IL 64332A0 IL 64332 A IL64332 A IL 64332A IL 6433281 A IL6433281 A IL 6433281A IL 64332 A0 IL64332 A0 IL 64332A0
Authority
IL
Israel
Prior art keywords
dichlorodiethylamino
phenylalanine
compounds
tumor activity
cancer tumor
Prior art date
Application number
IL64332A
Other languages
English (en)
Original Assignee
Proter Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proter Spa filed Critical Proter Spa
Publication of IL64332A0 publication Critical patent/IL64332A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL64332A 1980-11-28 1981-11-22 Compounds of dichlorodiethylamino-phenylalanine with anti-cancer tumor activity IL64332A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT26305/80A IT1134503B (it) 1980-11-28 1980-11-28 Composti della diclorodietilaminofenilalanina ad azione antitumorale

Publications (1)

Publication Number Publication Date
IL64332A0 true IL64332A0 (en) 1982-02-28

Family

ID=11219187

Family Applications (1)

Application Number Title Priority Date Filing Date
IL64332A IL64332A0 (en) 1980-11-28 1981-11-22 Compounds of dichlorodiethylamino-phenylalanine with anti-cancer tumor activity

Country Status (11)

Country Link
US (1) US4428875A (fr)
EP (1) EP0056565B1 (fr)
JP (1) JPS57120559A (fr)
AT (1) ATE10621T1 (fr)
AU (1) AU547065B2 (fr)
CA (1) CA1180697A (fr)
DE (1) DE3167653D1 (fr)
ES (1) ES8206449A1 (fr)
IL (1) IL64332A0 (fr)
IT (1) IT1134503B (fr)
PT (1) PT73950B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011777A (en) * 1985-01-25 1991-04-30 Oncogen Vectors encoding brain derivable polypeptide factors
US4777270A (en) * 1985-01-25 1988-10-11 Pfizer Inc. Macrocyclic polyether carboxylic acids
US4714683A (en) * 1985-01-25 1987-12-22 Oncogen Polypeptide tumor inhibitors and antibodies thereto
US4921941A (en) * 1987-07-01 1990-05-01 Schering Corporation Orally active antiandrogens
US4902781A (en) * 1987-11-24 1990-02-20 Taisho Pharmaceutical Co., Ltd. Novel tripetide derivatives
GR1000608B (el) * 1988-07-21 1992-08-31 Erba Carlo Spa Μεθοδος για την παρασκευη ανταγωνιστων bombesin.
JPH03118130U (fr) * 1990-03-16 1991-12-05
JPH0727940U (ja) * 1993-10-29 1995-05-23 盟和産業株式会社 車輌用フロアマット
DE60141398D1 (de) * 2000-06-13 2010-04-08 Oncopeptides Ab Melphalan-derivate und ihre verwendung als chemotherapeutika gegen krebs
CN100491339C (zh) * 2007-04-20 2009-05-27 苏州市立德化学有限公司 一种抗肿瘤药物美法仑的合成工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU452986B2 (en) * 1971-11-03 1974-09-19 Istituto Sieroterapico Milanese Serafino Belfanti OLIGOPEPTIDES CONTAINING m-jpi (2 CHLORETHYL) AMINO] L-PHENYLALANINE
DE2510634A1 (de) 1975-03-12 1976-09-23 Boehringer Mannheim Gmbh L-3-(3,4-dihydroxy-phenyl)-2- methyl-alanin-peptide und verfahren zu deren herstellung
FR2381023A1 (fr) 1977-02-18 1978-09-15 Delalande Sa Nouveaux oligopeptides trifluoromethyles derives de la l-alanine, leur procede de preparation et leur application en therapeutique
US4216208A (en) * 1978-07-31 1980-08-05 Proter S.P.A. N-Acyl derivatives of glucosamines having antitumor chemotherapeutic activity

Also Published As

Publication number Publication date
IT8026305A0 (it) 1980-11-28
JPH0243727B2 (fr) 1990-10-01
EP0056565B1 (fr) 1984-12-05
EP0056565A1 (fr) 1982-07-28
AU547065B2 (en) 1985-10-03
ES506871A0 (es) 1982-08-16
PT73950A (fr) 1981-12-01
DE3167653D1 (en) 1985-01-17
PT73950B (fr) 1983-04-18
CA1180697A (fr) 1985-01-08
AU7739781A (en) 1982-06-03
US4428875A (en) 1984-01-31
IT1134503B (it) 1986-08-13
ATE10621T1 (de) 1984-12-15
ES8206449A1 (es) 1982-08-16
JPS57120559A (en) 1982-07-27

Similar Documents

Publication Publication Date Title
NO932954L (no) 2,4-diaminokinazolin-derivater for aa oppnaa oeket antitumoraktivitet
PT1391206E (pt) Composições farmacêuticas compreendendo trióxido de arsénico para o tratamento de linfoma não-hodgkin
ES8801546A1 (es) Un procedimiento para la preparacion de compuesto de 2,2-difluoronucleosidos.
ES2187519T3 (es) 7-halogeno-y 7beta,8beta-metano-taxoles, uso antineoplasico y composiciones farmaceuticas que los contienen.
ZA814062B (en) Novel antihistamines
DK669088D0 (da) Fremgangsmaade og praeparat til forbedring af erkendelsesfunktionen
HK67694A (en) 1,2 bis(aminomethyl) cyclobutane-platinum-complexes
IN170909B (fr)
IL64332A0 (en) Compounds of dichlorodiethylamino-phenylalanine with anti-cancer tumor activity
ATE27457T1 (de) 1,2,4-triazine und pyrazin-derivate.
NO862353L (no) Human tumornekrosefaktor.
IL97055A0 (en) Pharmaceutical compositions for sensitizing tumor cells comprising quinazolinedione derivatives
FI870415A (fi) Terapeutiskt anvaendbara /2,2-bis(aminometyl)-1,3-propandiol-n,n')-platinakomplex och deras framstaellning.
SE8302519D0 (sv) Solfilterkompositioner
HUT43495A (en) Process for production and compound for treating of cancer and beningn tumor
MX9201763A (es) Derivados de pirimidina para aumentar la actividad antitumores.
AU3260093A (en) Use of creatine phosphate or phosphoenolpyruvic acid for the treatment of tumours
GB2185017A (en) Seco-sterol compounds effective in inducing the differentiation of malignant cells
SE8902340L (sv) Mitomycinfosfat-derivat
IL89901A0 (en) Strobilurine derivatives
AU7869281A (en) Treatment of malignant tumours with 2- -d-ribofuranosyl- thiazole-4-carboxamide + similar compounds
EP0793499A4 (fr) Procede et composition permettant de reduire le developpement d'une tumeur par association d'un compose du taxane et d'un compose du tellure et/ou du selenium
GB2134906A (en) Condensation products of a-aminoisopropylphenylketone through carbonyl c=o-conjugation with substituted amines, or functional substituted hydrazines, or with derivatives of amino acids
WO1992015601A3 (fr) Analogues antitumoraux d'heteroanthracycline

Legal Events

Date Code Title Description
RH Patent void