IL63747A - Cardenolide bis-digitoxosides,processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents
Cardenolide bis-digitoxosides,processes for the preparation thereof and pharmaceutical compositions containing themInfo
- Publication number
- IL63747A IL63747A IL63747A IL6374781A IL63747A IL 63747 A IL63747 A IL 63747A IL 63747 A IL63747 A IL 63747A IL 6374781 A IL6374781 A IL 6374781A IL 63747 A IL63747 A IL 63747A
- Authority
- IL
- Israel
- Prior art keywords
- digitoxosides
- cardenolide
- bis
- processes
- preparation
- Prior art date
Links
- TYYDXNISHGVDGA-UHFFFAOYSA-N Corotoxigenin Natural products CC12CCC3C(CCC4CC(O)CCC34C=O)C1CCC2C5=CC(=O)OC5 TYYDXNISHGVDGA-UHFFFAOYSA-N 0.000 title 1
- JIUWTCXNUNHEGP-GJHPUSIBSA-N cardenolide Chemical compound C1([C@H]2CC[C@@H]3[C@H]4[C@@H]([C@]5(CCCCC5CC4)C)CC[C@@]32C)=CC(=O)OC1 JIUWTCXNUNHEGP-GJHPUSIBSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 230000029142 excretion Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
- C07J19/005—Glycosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Silicon Polymers (AREA)
- Medicinal Preparation (AREA)
- Magnetic Record Carriers (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803034658 DE3034658A1 (de) | 1980-09-13 | 1980-09-13 | Neue alkylderivate von cardenolid-bis-digitoxosiden, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL63747A0 IL63747A0 (en) | 1981-12-31 |
| IL63747A true IL63747A (en) | 1984-09-30 |
Family
ID=6111912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL63747A IL63747A (en) | 1980-09-13 | 1981-09-06 | Cardenolide bis-digitoxosides,processes for the preparation thereof and pharmaceutical compositions containing them |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4353895A (es) |
| EP (1) | EP0047928B1 (es) |
| JP (1) | JPS5781500A (es) |
| AT (1) | ATE4720T1 (es) |
| AU (1) | AU539401B2 (es) |
| CA (1) | CA1164455A (es) |
| DE (2) | DE3034658A1 (es) |
| ES (1) | ES8205816A1 (es) |
| FI (1) | FI70719C (es) |
| HU (1) | HU182751B (es) |
| IL (1) | IL63747A (es) |
| ZA (1) | ZA816178B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT384227B (de) * | 1982-05-05 | 1987-10-12 | Chemie Linz Ag | Verfahren zur herstellung von beta-methyldigoxin |
| US7361478B2 (en) * | 2001-11-20 | 2008-04-22 | Allergan, Inc. | High-throughput screen for identifying selective persistent sodium channels channel blockers |
| DE10157558B4 (de) * | 2001-11-23 | 2007-06-21 | Air Liquide Deutschland Gmbh | Farbindikator für Kohlendioxid |
| US20060069043A1 (en) * | 2004-09-29 | 2006-03-30 | Somberg John C | Chiral separation, characterization and biological action of optically active isomers of digoxin |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3458628A (en) * | 1966-02-11 | 1969-07-29 | Boehringer & Soehne Gmbh | Acovenoside derivatives |
| NL130587C (es) * | 1966-12-22 | |||
| DE2343400C3 (de) * | 1973-08-29 | 1979-11-08 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur 12 ß -Hydroxylierung von Digitalis-Glykosiden der A-Reihe |
-
1980
- 1980-09-13 DE DE19803034658 patent/DE3034658A1/de not_active Withdrawn
-
1981
- 1981-07-30 US US06/288,442 patent/US4353895A/en not_active Expired - Fee Related
- 1981-09-04 AT AT81106938T patent/ATE4720T1/de not_active IP Right Cessation
- 1981-09-04 EP EP81106938A patent/EP0047928B1/de not_active Expired
- 1981-09-04 DE DE8181106938T patent/DE3160968D1/de not_active Expired
- 1981-09-06 IL IL63747A patent/IL63747A/xx unknown
- 1981-09-07 AU AU74994/81A patent/AU539401B2/en not_active Ceased
- 1981-09-07 ZA ZA816178A patent/ZA816178B/xx unknown
- 1981-09-08 CA CA000385327A patent/CA1164455A/en not_active Expired
- 1981-09-08 FI FI812777A patent/FI70719C/fi not_active IP Right Cessation
- 1981-09-09 ES ES505328A patent/ES8205816A1/es not_active Expired
- 1981-09-11 JP JP56142583A patent/JPS5781500A/ja active Pending
- 1981-09-11 HU HU812636A patent/HU182751B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU182751B (en) | 1984-03-28 |
| EP0047928B1 (de) | 1983-09-21 |
| DE3034658A1 (de) | 1982-04-29 |
| ES505328A0 (es) | 1982-08-16 |
| JPS5781500A (en) | 1982-05-21 |
| CA1164455A (en) | 1984-03-27 |
| AU539401B2 (en) | 1984-09-27 |
| IL63747A0 (en) | 1981-12-31 |
| FI70719C (fi) | 1986-10-06 |
| AU7499481A (en) | 1982-03-25 |
| DE3160968D1 (en) | 1983-10-27 |
| FI812777L (fi) | 1982-03-14 |
| ATE4720T1 (de) | 1983-10-15 |
| US4353895A (en) | 1982-10-12 |
| ES8205816A1 (es) | 1982-08-16 |
| FI70719B (fi) | 1986-06-26 |
| EP0047928A1 (de) | 1982-03-24 |
| ZA816178B (en) | 1982-09-29 |
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