IL63429A0 - Guanylated aminoglycosides,their production and pharmaceutical compositions containing them - Google Patents

Guanylated aminoglycosides,their production and pharmaceutical compositions containing them

Info

Publication number
IL63429A0
IL63429A0 IL63429A IL6342981A IL63429A0 IL 63429 A0 IL63429 A0 IL 63429A0 IL 63429 A IL63429 A IL 63429A IL 6342981 A IL6342981 A IL 6342981A IL 63429 A0 IL63429 A0 IL 63429A0
Authority
IL
Israel
Prior art keywords
guanylated
aminoglycosides
production
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL63429A
Other languages
English (en)
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL63429A0 publication Critical patent/IL63429A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IL63429A 1980-07-28 1981-07-27 Guanylated aminoglycosides,their production and pharmaceutical compositions containing them IL63429A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH575680 1980-07-28
CH777880 1980-10-17
CH184281 1981-03-18

Publications (1)

Publication Number Publication Date
IL63429A0 true IL63429A0 (en) 1981-10-30

Family

ID=27173293

Family Applications (1)

Application Number Title Priority Date Filing Date
IL63429A IL63429A0 (en) 1980-07-28 1981-07-27 Guanylated aminoglycosides,their production and pharmaceutical compositions containing them

Country Status (9)

Country Link
EP (1) EP0056408A1 (xx)
JP (1) JPS57501084A (xx)
CS (1) CS228516B2 (xx)
GR (1) GR74312B (xx)
IL (1) IL63429A0 (xx)
IT (1) IT1171411B (xx)
PT (1) PT73428B (xx)
WO (1) WO1982000464A1 (xx)
YU (1) YU184481A (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007064954A2 (en) 2005-12-02 2007-06-07 Isis Pharmaceuticals, Inc. Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
EP2324076B1 (en) 2008-07-31 2017-11-01 3M Innovative Properties Company Fluoropolymer compositions and method of making and using thereof
EP2315802A4 (en) * 2008-07-31 2012-04-18 3M Innovative Properties Co AZIUM COMPOSITIONS AND METHOD FOR THEIR PREPARATION AND USE
WO2010030690A1 (en) 2008-09-10 2010-03-18 Isis Pharmaceuticals, Inc. Antibacterial 4,6-substituted 6', 6" and 1 modified aminoglycoside analogs
WO2010030704A2 (en) 2008-09-10 2010-03-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042850A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042851A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
EP2486044A2 (en) 2009-10-09 2012-08-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
TW201304784A (zh) 2010-11-17 2013-02-01 Achaogen Inc 抗菌性胺基糖苷類似物
CN116462721B (zh) * 2023-04-18 2024-02-02 江南大学 抗菌性氨基糖苷衍生物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1087537A (en) * 1975-08-21 1980-10-14 John H. E. J. Martin Antibiotic bm123 and production thereof
JPS5488241A (en) * 1977-12-21 1979-07-13 Kyowa Hakko Kogyo Co Ltd Novel fortimicin a derivative

Also Published As

Publication number Publication date
JPS57501084A (xx) 1982-06-24
IT1171411B (it) 1987-06-10
IT8148952A0 (it) 1981-07-22
PT73428A (en) 1981-08-01
GR74312B (xx) 1984-06-22
WO1982000464A1 (en) 1982-02-18
PT73428B (en) 1983-01-13
CS228516B2 (en) 1984-05-14
EP0056408A1 (en) 1982-07-28
YU184481A (en) 1983-09-30

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