IL62421A - Oxiranebutanoic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
Oxiranebutanoic acid derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL62421A IL62421A IL62421A IL6242181A IL62421A IL 62421 A IL62421 A IL 62421A IL 62421 A IL62421 A IL 62421A IL 6242181 A IL6242181 A IL 6242181A IL 62421 A IL62421 A IL 62421A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- acid derivatives
- oxiranebutanoic
- Prior art date
Links
- ZRRIBVBIRXIHHN-UHFFFAOYSA-N 4-(oxiran-2-yl)butanoic acid Chemical class OC(=O)CCCC1CO1 ZRRIBVBIRXIHHN-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 238000003786 synthesis reaction Methods 0.000 abstract 2
- TWJDCTNDUKKEMU-ARJAWSKDSA-N (z)-pent-2-en-4-yn-1-ol Chemical compound OC\C=C/C#C TWJDCTNDUKKEMU-ARJAWSKDSA-N 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/46—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings substituted on the ring sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
- C07C29/10—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
- C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
- C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
- C07D303/42—Acyclic compounds having a chain of seven or more carbon atoms, e.g. epoxidised fats
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/133,180 US4311645A (en) | 1980-03-24 | 1980-03-24 | Synthesis of SRS-active compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL62421A0 IL62421A0 (en) | 1981-05-20 |
| IL62421A true IL62421A (en) | 1984-10-31 |
Family
ID=22457377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL62421A IL62421A (en) | 1980-03-24 | 1981-03-18 | Oxiranebutanoic acid derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4311645A (xx) |
| EP (1) | EP0036663B1 (xx) |
| JP (1) | JPS56145279A (xx) |
| AT (1) | ATE9341T1 (xx) |
| AU (1) | AU541254B2 (xx) |
| CA (1) | CA1175853A (xx) |
| DE (1) | DE3165920D1 (xx) |
| DK (1) | DK131481A (xx) |
| IE (1) | IE51038B1 (xx) |
| IL (1) | IL62421A (xx) |
| NZ (1) | NZ196572A (xx) |
| PH (1) | PH15895A (xx) |
| ZA (1) | ZA811936B (xx) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2147583B (en) * | 1981-06-18 | 1985-12-24 | Lilly Industries Ltd | Improvements in or relating to organic compounds |
| US4513005A (en) * | 1981-06-18 | 1985-04-23 | Lilly Industries Limited | SRS-A antagonists |
| JPS58213751A (ja) * | 1982-06-04 | 1983-12-12 | Suntory Ltd | 新規ロイコトリエン類縁化合物及びその合成中間体 |
| US4448729A (en) * | 1982-08-25 | 1984-05-15 | American Home Products Corporation | Leucotriene antagonists |
| US4552893A (en) * | 1983-03-07 | 1985-11-12 | Smithkline Beckman Corporation | Leukotriene antagonists |
| DK130984A (da) * | 1983-03-07 | 1984-09-08 | Smithkline Beckman Corp | Leukotrien-antagonister |
| ZA854550B (en) * | 1984-06-18 | 1986-04-30 | Smithkline Beckman Corp | Leukotriene antagonists |
| US5243096A (en) * | 1990-06-14 | 1993-09-07 | Asahi Denka Kogyo K.K. | Optically active pentane derivatives and intermediates thereof, and process for manufacturing same |
| WO1995032940A1 (en) * | 1994-05-27 | 1995-12-07 | Howard University | Process for the production of olefin acid anhydrides and esters thereof |
| US20050215640A1 (en) | 2004-03-26 | 2005-09-29 | Baxter Jeffrey H | HMB compositions and uses thereof |
| WO2007075605A2 (en) | 2005-12-19 | 2007-07-05 | Abbott Laboratories | Use of beta-hydroxy-beta-methylbutyrate to modulate the imbalance in type and type 2 cytokine production |
| US20100247461A1 (en) * | 2009-01-20 | 2010-09-30 | Signum Biosciences, Inc. | Anti-inflammatory complexes |
| RU2012125878A (ru) | 2010-01-29 | 2014-03-10 | Эбботт Лэборетриз | Асептически упакованные питательные жидкости, содержащие бета-гидрокси-бета-метилбутират (гмб) |
| US9693577B2 (en) | 2010-01-29 | 2017-07-04 | Abbott Laboratories | Method of preparing a nutritional powder comprising spray dried HMB |
| JP5892948B2 (ja) | 2010-01-29 | 2016-03-23 | アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ | カルシウムｈｍｂを含む栄養エマルジョン |
| TWI526161B (zh) | 2010-06-10 | 2016-03-21 | 亞培公司 | 包含鈣ｈｍｂ及可溶性蛋白質之實質上透明營養液 |
| CN110724033B (zh) * | 2019-10-19 | 2023-06-09 | 滁州学院 | 一种无外源碱Suzuki反应制备醇的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1384530A (en) * | 1971-07-29 | 1975-02-19 | Fisons Ltd | Chromone derivatives |
| US4174402A (en) * | 1978-08-17 | 1979-11-13 | Sterling Drug Inc. | Method for the prophylaxis of SRS-A-induced symptoms |
-
1980
- 1980-03-24 US US06/133,180 patent/US4311645A/en not_active Expired - Lifetime
-
1981
- 1981-03-18 IL IL62421A patent/IL62421A/xx unknown
- 1981-03-20 CA CA000373493A patent/CA1175853A/en not_active Expired
- 1981-03-20 NZ NZ196572A patent/NZ196572A/en unknown
- 1981-03-23 PH PH25396A patent/PH15895A/en unknown
- 1981-03-23 IE IE637/81A patent/IE51038B1/en unknown
- 1981-03-23 JP JP4053281A patent/JPS56145279A/ja active Pending
- 1981-03-23 DE DE8181102184T patent/DE3165920D1/de not_active Expired
- 1981-03-23 ZA ZA00811936A patent/ZA811936B/xx unknown
- 1981-03-23 AT AT81102184T patent/ATE9341T1/de not_active IP Right Cessation
- 1981-03-23 EP EP81102184A patent/EP0036663B1/de not_active Expired
- 1981-03-23 DK DK131481A patent/DK131481A/da not_active Application Discontinuation
- 1981-03-24 AU AU68672/81A patent/AU541254B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ZA811936B (en) | 1982-04-28 |
| AU6867281A (en) | 1981-10-01 |
| US4311645A (en) | 1982-01-19 |
| IE51038B1 (en) | 1986-09-17 |
| DK131481A (da) | 1981-09-25 |
| AU541254B2 (en) | 1985-01-03 |
| ATE9341T1 (de) | 1984-09-15 |
| IE810637L (en) | 1981-09-24 |
| NZ196572A (en) | 1984-05-31 |
| PH15895A (en) | 1983-04-15 |
| DE3165920D1 (en) | 1984-10-18 |
| EP0036663A1 (de) | 1981-09-30 |
| EP0036663B1 (de) | 1984-09-12 |
| IL62421A0 (en) | 1981-05-20 |
| CA1175853A (en) | 1984-10-09 |
| JPS56145279A (en) | 1981-11-11 |
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