IL60758A0 - Carbapenem derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Carbapenem derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL60758A0
IL60758A0 IL60758A IL6075880A IL60758A0 IL 60758 A0 IL60758 A0 IL 60758A0 IL 60758 A IL60758 A IL 60758A IL 6075880 A IL6075880 A IL 6075880A IL 60758 A0 IL60758 A0 IL 60758A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
carbapenem derivatives
carbapenem
Prior art date
Application number
IL60758A
Other languages
English (en)
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of IL60758A0 publication Critical patent/IL60758A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL60758A 1979-08-10 1980-08-05 Carbapenem derivatives,their preparation and pharmaceutical compositions containing them IL60758A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7927901 1979-08-10
GB8012724 1980-04-17

Publications (1)

Publication Number Publication Date
IL60758A0 true IL60758A0 (en) 1980-10-26

Family

ID=26272503

Family Applications (1)

Application Number Title Priority Date Filing Date
IL60758A IL60758A0 (en) 1979-08-10 1980-08-05 Carbapenem derivatives,their preparation and pharmaceutical compositions containing them

Country Status (12)

Country Link
US (1) US4473578A (xx)
EP (2) EP0024832B1 (xx)
AU (1) AU6119680A (xx)
CA (1) CA1175841A (xx)
DE (1) DE3070269D1 (xx)
DK (1) DK344080A (xx)
ES (2) ES494136A0 (xx)
FI (1) FI802446A (xx)
GR (1) GR69935B (xx)
IL (1) IL60758A0 (xx)
NO (1) NO802377L (xx)
NZ (1) NZ194584A (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0072121A1 (en) * 1981-08-08 1983-02-16 Beecham Group Plc Beta-lactam antibiotics
US4552873A (en) * 1981-08-19 1985-11-12 Sankyo Company Limited Carbapenem compounds, and compositions containing them
EP0079167A1 (en) * 1981-11-09 1983-05-18 Beecham Group Plc A carbapenem compound, preparation and use
DE3274861D1 (en) * 1981-11-10 1987-02-05 Shionogi & Co Pluracidomycin b,c, and d and analogs thereof, their production and a microorganism for use therein
US4556517A (en) * 1981-12-29 1985-12-03 Shionogi & Co., Ltd. Carbapenem derivatives
DE3372773D1 (de) * 1982-03-26 1987-09-03 Hoechst Uk Ltd 7-oxo-4-thia-1-azabicyclo(3,2,0)heptane derivatives
US4683301A (en) * 1982-04-08 1987-07-28 Bristol-Myers Company Carbapenem antibiotics
US4642341A (en) * 1982-04-09 1987-02-10 Bristol-Myers Company Carbapenem antibiotics
US4710568A (en) * 1982-04-09 1987-12-01 Bristol-Myers Company Carbapenem antibiotics
US4665170A (en) * 1982-06-18 1987-05-12 Bristol-Myers Company Carbapenem antibiotics
US4640799A (en) * 1982-06-18 1987-02-03 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
US4732977A (en) * 1982-09-28 1988-03-22 Bristol Myers Company Carbapenem antibiotics
US4746736A (en) * 1982-09-28 1988-05-24 Bristol-Myers Company Carbapenem antibiotics
DE3382761T2 (de) * 1982-11-29 1995-03-09 Schering Corp Verfahren zur Herstellung von Penem-Verbindungen.
EP0137403A3 (en) * 1983-09-28 1987-04-15 Takeda Chemical Industries, Ltd. Carbapenems, their production and use
US4698339A (en) * 1983-09-28 1987-10-06 Takeda Chemical Industries, Ltd. Carbapenems, their production and use
ZA848416B (en) * 1983-11-10 1986-06-25 Dow Chemical Co Fluorophenoxy compounds,herbicidal compositions and methods
US4717728A (en) * 1983-11-21 1988-01-05 Merck & Co., Inc. Cyclic amidinyl and cyclic guanidinyl thio carbapenems

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1531141A (en) * 1976-08-17 1978-11-01 Beecham Group Ltd Beta-lactam antibiotics
NL7802826A (nl) * 1977-04-08 1978-10-10 Merck & Co Inc Thienamycinederivaat, werkwijze voor het bereiden daarvan, alsmede farmaceutische preparaten.
US4235917A (en) * 1977-05-05 1980-11-25 Merck & Co., Inc. N-Alkyl-N-acyl derivatives of thienamycin
EP0001567B1 (en) * 1977-10-13 1981-12-02 Sanraku-Ocean Co., Ltd. Thienamycin related antibiotics ps-6 and ps-7, process for their production and compositions containing them
US4347367A (en) * 1977-10-19 1982-08-31 Merck & Co., Inc. 3-Substituted-6-(1'-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
US4347368A (en) * 1977-10-19 1982-08-31 Merck & Co., Inc. 3-Substituted-6-substituted-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
EP0030392B1 (en) * 1978-01-19 1984-05-16 Beecham Group Plc Intermediates for use in the preparation of carbapenems
EP0004132A1 (en) * 1978-03-04 1979-09-19 Beecham Group Plc Esters of beta-lactam antibiotics, a process for their preparation pharmaceutical compositions containing them and the compounds for use as antibacterial agents
US4203902A (en) * 1978-04-21 1980-05-20 Merck & Co., Inc. Process for preparing 6- and 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids
EP0005349A1 (en) * 1978-05-06 1979-11-14 Beecham Group Plc Alkylcarbapenems, their preparation, use in pharmaceutical compositions and intermediates
DE2963717D1 (en) * 1978-05-06 1982-11-04 Beecham Group Plc Carbapenem derivatives, a process for their preparation and pharmaceutical compositions containing them
DE2963580D1 (en) * 1978-08-02 1982-10-21 Beecham Group Plc Beta-lactam antibacterial agents, a process for their preparation and pharmaceutical compositions containing them
EP0008888B1 (en) * 1978-08-23 1983-09-21 Beecham Group Plc Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
DE2961882D1 (en) * 1978-08-25 1982-03-04 Beecham Group Plc Beta-lactam anti-bacterials, compositions containing them and a process for their preparation
EP0008885B1 (en) * 1978-09-09 1983-11-30 Beecham Group Plc Beta-lactam compounds, their preparation and use
EP0011173B1 (en) * 1978-11-01 1983-05-11 Sanraku-Ocean Co., Ltd. Process for producing antibiotic beta-lactam compounds
EP0017992A1 (en) * 1979-04-19 1980-10-29 Merck & Co. Inc. 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates
US4376774A (en) * 1979-05-29 1983-03-15 Merck & Co., Inc. Antibiotic N-heterocyclyl thienamycin

Also Published As

Publication number Publication date
ES8106308A1 (es) 1981-08-01
EP0055990B1 (en) 1986-06-11
EP0024832B1 (en) 1985-03-13
ES499856A0 (es) 1982-01-16
GR69935B (xx) 1982-07-21
CA1175841A (en) 1984-10-09
EP0055990A1 (en) 1982-07-14
NZ194584A (en) 1983-05-31
EP0024832A1 (en) 1981-03-11
ES8202010A1 (es) 1982-01-16
AU6119680A (en) 1981-02-12
US4473578A (en) 1984-09-25
DK344080A (da) 1981-02-11
FI802446A (fi) 1981-02-11
NO802377L (no) 1981-02-11
ES494136A0 (es) 1981-08-01
DE3070269D1 (en) 1985-04-18

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