DE3070269D1 - Beta-lactam antibiotics, their preparation, pharmaceutical compositions containing them and their preparation - Google Patents

Beta-lactam antibiotics, their preparation, pharmaceutical compositions containing them and their preparation

Info

Publication number
DE3070269D1
DE3070269D1 DE8080302659T DE3070269T DE3070269D1 DE 3070269 D1 DE3070269 D1 DE 3070269D1 DE 8080302659 T DE8080302659 T DE 8080302659T DE 3070269 T DE3070269 T DE 3070269T DE 3070269 D1 DE3070269 D1 DE 3070269D1
Authority
DE
Germany
Prior art keywords
preparation
beta
pharmaceutical compositions
compositions containing
lactam antibiotics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080302659T
Other languages
English (en)
Inventor
David Francis Corbett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of DE3070269D1 publication Critical patent/DE3070269D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8080302659T 1979-08-10 1980-08-04 Beta-lactam antibiotics, their preparation, pharmaceutical compositions containing them and their preparation Expired DE3070269D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7927901 1979-08-10
GB8012724 1980-04-17

Publications (1)

Publication Number Publication Date
DE3070269D1 true DE3070269D1 (en) 1985-04-18

Family

ID=26272503

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080302659T Expired DE3070269D1 (en) 1979-08-10 1980-08-04 Beta-lactam antibiotics, their preparation, pharmaceutical compositions containing them and their preparation

Country Status (12)

Country Link
US (1) US4473578A (de)
EP (2) EP0055990B1 (de)
AU (1) AU6119680A (de)
CA (1) CA1175841A (de)
DE (1) DE3070269D1 (de)
DK (1) DK344080A (de)
ES (2) ES8106308A1 (de)
FI (1) FI802446A (de)
GR (1) GR69935B (de)
IL (1) IL60758A0 (de)
NO (1) NO802377L (de)
NZ (1) NZ194584A (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0072121A1 (de) * 1981-08-08 1983-02-16 Beecham Group Plc Beta-Lactam Antibiotika
US4552873A (en) * 1981-08-19 1985-11-12 Sankyo Company Limited Carbapenem compounds, and compositions containing them
EP0079167A1 (de) * 1981-11-09 1983-05-18 Beecham Group Plc Carbapenem-Verbindung, Herstellung und Verwendung
EP0079244B1 (de) * 1981-11-10 1986-12-30 Shionogi & Co., Ltd. Pluracidomycin B,C und D und deren Analoge, ihre Herstellung und ein dabei verwendbarer Mikroorganismus
US4556517A (en) * 1981-12-29 1985-12-03 Shionogi & Co., Ltd. Carbapenem derivatives
EP0091576B1 (de) * 1982-03-26 1987-07-29 Hoechst Uk Limited 7-Oxo-4-thia-1-azabicyclo(3,2,0)Heptan-Derivate
US4683301A (en) * 1982-04-08 1987-07-28 Bristol-Myers Company Carbapenem antibiotics
US4710568A (en) * 1982-04-09 1987-12-01 Bristol-Myers Company Carbapenem antibiotics
US4642341A (en) * 1982-04-09 1987-02-10 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
US4665170A (en) * 1982-06-18 1987-05-12 Bristol-Myers Company Carbapenem antibiotics
US4640799A (en) * 1982-06-18 1987-02-03 Bristol-Myers Company Carbapenem antibiotics
US4732977A (en) * 1982-09-28 1988-03-22 Bristol Myers Company Carbapenem antibiotics
US4746736A (en) * 1982-09-28 1988-05-24 Bristol-Myers Company Carbapenem antibiotics
EP0345827A1 (de) * 1982-11-29 1989-12-13 Schering Corporation Verfahren zur Herstellung von Penem-Verbindungen
EP0137403A3 (de) * 1983-09-28 1987-04-15 Takeda Chemical Industries, Ltd. Carbapenem-Verbindungen, ihre Herstellung und Verwendung
US4698339A (en) * 1983-09-28 1987-10-06 Takeda Chemical Industries, Ltd. Carbapenems, their production and use
ZA848416B (en) * 1983-11-10 1986-06-25 Dow Chemical Co Fluorophenoxy compounds,herbicidal compositions and methods
US4717728A (en) * 1983-11-21 1988-01-05 Merck & Co., Inc. Cyclic amidinyl and cyclic guanidinyl thio carbapenems

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1531141A (en) * 1976-08-17 1978-11-01 Beecham Group Ltd Beta-lactam antibiotics
NL7802826A (nl) * 1977-04-08 1978-10-10 Merck & Co Inc Thienamycinederivaat, werkwijze voor het bereiden daarvan, alsmede farmaceutische preparaten.
US4235917A (en) * 1977-05-05 1980-11-25 Merck & Co., Inc. N-Alkyl-N-acyl derivatives of thienamycin
DE2861413D1 (en) * 1977-10-13 1982-01-28 Sanraku Ocean Co Thienamycin related antibiotics ps-6 and ps-7, process for their production and compositions containing them
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
US4347368A (en) * 1977-10-19 1982-08-31 Merck & Co., Inc. 3-Substituted-6-substituted-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
US4347367A (en) * 1977-10-19 1982-08-31 Merck & Co., Inc. 3-Substituted-6-(1'-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid
EP0003740B1 (de) * 1978-01-19 1982-01-27 Beecham Group Plc Beta-Lactamantibiotika, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
EP0004132A1 (de) * 1978-03-04 1979-09-19 Beecham Group Plc Beta-Lactamester Antibiotika, Verfahren zu ihrer Herstellung und ihre Verwendung in pharmazeutischen Zubereitungen
US4203902A (en) * 1978-04-21 1980-05-20 Merck & Co., Inc. Process for preparing 6- and 2-substituted-1-carbadethiapen-2-em-3-carboxylic acids
EP0005348B1 (de) * 1978-05-06 1982-09-22 Beecham Group Plc Carbapenemderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
EP0005349A1 (de) * 1978-05-06 1979-11-14 Beecham Group Plc Alkylcarbapeneme, ihre Herstellung, pharmazeutische Zubereitungen und Zwischenprodukte
EP0007753B1 (de) * 1978-08-02 1982-08-25 Beecham Group Plc Antibakterielle Beta-Lactam-Verbindungen, ein Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
EP0008888B1 (de) * 1978-08-23 1983-09-21 Beecham Group Plc Antibakterielle Beta-Lactam-Verbindungen, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
DE2961882D1 (en) * 1978-08-25 1982-03-04 Beecham Group Plc Beta-lactam anti-bacterials, compositions containing them and a process for their preparation
EP0008885B1 (de) * 1978-09-09 1983-11-30 Beecham Group Plc Beta-Lactam-Verbindungen, ihre Herstellung und Verwendung
EP0011173B1 (de) * 1978-11-01 1983-05-11 Sanraku-Ocean Co., Ltd. Verfahren zur Herstellung von antibiotischen Beta-Lactam-Verbindungen
DK165280A (da) * 1979-04-19 1980-10-20 Merck & Co Inc Fremgangsmaade til fremstilling af 2- og 6-substituerede 1-carbadethiapen-2-em-3-carboxylsyrer og mellemprodukter til brug ved udoevelse af fremgangsmaaden
US4376774A (en) * 1979-05-29 1983-03-15 Merck & Co., Inc. Antibiotic N-heterocyclyl thienamycin

Also Published As

Publication number Publication date
EP0055990B1 (de) 1986-06-11
ES499856A0 (es) 1982-01-16
NZ194584A (en) 1983-05-31
EP0024832B1 (de) 1985-03-13
NO802377L (no) 1981-02-11
IL60758A0 (en) 1980-10-26
ES494136A0 (es) 1981-08-01
EP0055990A1 (de) 1982-07-14
ES8202010A1 (es) 1982-01-16
EP0024832A1 (de) 1981-03-11
AU6119680A (en) 1981-02-12
GR69935B (de) 1982-07-21
US4473578A (en) 1984-09-25
FI802446A (fi) 1981-02-11
ES8106308A1 (es) 1981-08-01
CA1175841A (en) 1984-10-09
DK344080A (da) 1981-02-11

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee