IL60095A - Synergistic analgesic pharmaceutical compositions comprising nalbuphine and acetaminophen - Google Patents

Synergistic analgesic pharmaceutical compositions comprising nalbuphine and acetaminophen

Info

Publication number
IL60095A
IL60095A IL60095A IL6009580A IL60095A IL 60095 A IL60095 A IL 60095A IL 60095 A IL60095 A IL 60095A IL 6009580 A IL6009580 A IL 6009580A IL 60095 A IL60095 A IL 60095A
Authority
IL
Israel
Prior art keywords
nalbuphine
acetaminophen
pharmaceutical compositions
analgesic pharmaceutical
synergistic analgesic
Prior art date
Application number
IL60095A
Other languages
English (en)
Other versions
IL60095A0 (en
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of IL60095A0 publication Critical patent/IL60095A0/xx
Publication of IL60095A publication Critical patent/IL60095A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL60095A 1979-05-18 1980-05-16 Synergistic analgesic pharmaceutical compositions comprising nalbuphine and acetaminophen IL60095A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/040,281 US4237140A (en) 1979-05-18 1979-05-18 Analgesic mixture of nalbuphine and acetaminophen

Publications (2)

Publication Number Publication Date
IL60095A0 IL60095A0 (en) 1980-07-31
IL60095A true IL60095A (en) 1982-12-31

Family

ID=21910135

Family Applications (1)

Application Number Title Priority Date Filing Date
IL60095A IL60095A (en) 1979-05-18 1980-05-16 Synergistic analgesic pharmaceutical compositions comprising nalbuphine and acetaminophen

Country Status (12)

Country Link
US (1) US4237140A (Direct)
EP (1) EP0019282B1 (Direct)
JP (1) JPS55154917A (Direct)
AU (1) AU529764B2 (Direct)
CA (1) CA1139671A (Direct)
DE (1) DE3061597D1 (Direct)
HU (1) HU178867B (Direct)
IE (1) IE49988B1 (Direct)
IL (1) IL60095A (Direct)
NZ (1) NZ193695A (Direct)
PH (1) PH15265A (Direct)
ZA (1) ZA802916B (Direct)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322427A (en) * 1981-04-16 1982-03-30 Bristol-Myers Company Analgetic compositions and methods of use
US4366159A (en) * 1981-09-08 1982-12-28 Michael Richard Magruder Nalbuphine-narcotic analgesic composition and method of producing analgesia
US4407804A (en) * 1982-06-30 1983-10-04 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and indomethacin
US4404211A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and flurbiprofen
US4407805A (en) * 1982-06-30 1983-10-04 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and zomepirac
US4404208A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and tiflamizole
US4404209A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and sulindac
US4404210A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and ibuprofen
US4402962A (en) * 1982-06-30 1983-09-06 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and 4,5-bis(4-methoxyphenyl)-2-(trifluoromethylsulfonyl)-1H-imidazole
AU565634B2 (en) * 1982-06-30 1987-09-24 E.I. Du Pont De Nemours And Company Synergistic compositions of nalbuphine and non-narcotic analgesic compounds
US4777174A (en) * 1982-07-22 1988-10-11 Analgesic Associates Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
GB2134786B (en) * 1982-07-22 1986-05-08 Richardson Vicks Inc Improved analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
US4656177A (en) * 1982-07-22 1987-04-07 Analgesic Associates Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same
US4600579A (en) * 1983-06-07 1986-07-15 Mallinckrodt, Inc. N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same
US4722928A (en) * 1985-12-02 1988-02-02 E. I. Du Pont De Nemours And Company N-oxide prodrug derivatives of 3-hydroxy morphinans and partial morphinans having improved oral bioavailability, pharmaceutical compositions, and processes
RU2121346C1 (ru) 1991-09-06 1998-11-10 МакНейлэб, Инк. Композиция, включающая вещество трамадол и ацетаминофен, и способ лечения с ее использованием
US5558876A (en) * 1995-03-29 1996-09-24 Alcon Laboratories, Inc. Topical ophthalmic acidic drug formulations
US6348216B1 (en) * 1996-06-10 2002-02-19 Knoll Pharmaceutical Company Ibuprofen and narcotic analgesic compositions
US6361794B1 (en) 1996-06-12 2002-03-26 Basf Corporation Method of making ibuprofen and narcotic analgesic composition
US6375957B1 (en) 1997-12-22 2002-04-23 Euro-Celtique, S.A. Opioid agonist/opioid antagonist/acetaminophen combinations
WO1999032119A1 (en) 1997-12-22 1999-07-01 Euro-Celtique, S.A. Opioid agonist/antagonist combinations
KR20020071032A (ko) 2000-02-08 2002-09-11 유로-셀티크 소시에떼 아노뉨 오피오이드 효능제와 길항제를 함유하는 서방성 조성물
ES2361148T3 (es) 2001-05-11 2011-06-14 Endo Pharmaceuticals Inc. Forma de dosificación de opioides de liberación controlada resistente al abuso.
SI1416842T1 (sl) 2001-07-18 2009-06-30 Euro Celtique Sa Farmacevtske kombinacije oksikodona in naloksona
CA2457361C (en) 2001-08-06 2008-11-04 Christopher Breder Opioid agonist formulations with releasable and sequestered antagonist
US20030044458A1 (en) 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
US20030157168A1 (en) 2001-08-06 2003-08-21 Christopher Breder Sequestered antagonist formulations
DE20321531U1 (de) 2002-04-05 2007-11-22 Euro-Celtique S.A. Lagerstabiles pharmazeutisches Präparat, das Oxycodon und Naloxon umfaßt
AU2003270778B2 (en) 2002-09-20 2009-10-08 Alpharma Pharmaceuticals, Llc Sequestering subunit and related compositions and methods
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
TWI347201B (en) 2003-04-21 2011-08-21 Euro Celtique Sa Pharmaceutical products,uses thereof and methods for preparing the same
EP1604666A1 (en) 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD)
EP1702558A1 (en) 2005-02-28 2006-09-20 Euro-Celtique S.A. Method and device for the assessment of bowel function
EP1931315B1 (en) * 2005-08-24 2013-10-16 Penwest Pharmaceuticals Co. Sustained release formulations of nalbuphine
US8394812B2 (en) 2005-08-24 2013-03-12 Penwest Pharmaceuticals Co. Sustained release formulations of nalbuphine
KR20150029762A (ko) 2006-06-19 2015-03-18 알파마 파머슈티컬스 엘엘씨 약제학적 조성물
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
UY32487A (es) 2009-03-10 2010-06-30 Euro Celtique Sa Composiciones farmacéuticas de liberación inmediata comprendiendo oxicodona y naloxona
WO2015011189A1 (en) 2013-07-23 2015-01-29 Euro-Celtique S.A. A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
HRP20220978T1 (hr) 2013-12-24 2022-11-11 Virginia Commonwealth University Upotreba oksidiranih kolesterol sulfata (ocs) za liječenje disfunkcije bubrega
JOP20190094A1 (ar) * 2016-10-27 2019-04-25 Broad Inst Inc مركبات 1، 2، 4-تريازولون تحمل ثلاثة بدائل عند المواقع 2، 4، 5 مفيدة كمثبطات لديهيدروجيناز ثنائي هيدرو أوروتات (dhodh)
US11260048B2 (en) 2017-10-03 2022-03-01 The Schepens Eye Research Institute, Inc. Compounds and compositions for inhibiting retinal pigment epithelium degeneration and methods using the same
CN113164469A (zh) * 2018-09-03 2021-07-23 雅各生技有限公司 双那布扶林己二酸酯和乙酰胺酚的药物制剂及治疗疼痛的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL26896A (en) * 1966-01-19 1970-11-30 Endo Lab 14 - Hydroxynormorphinins and 14 - Hydroxynormorphinones
US4029798A (en) * 1975-06-02 1977-06-14 Sumitomo Chemical Company, Limited Analgetic composition
JPS5946205B2 (ja) * 1976-01-01 1984-11-10 科研製薬株式会社 ベンゾイル誘導体を有効成分とする消炎鎮痛剤

Also Published As

Publication number Publication date
DE3061597D1 (en) 1983-02-17
IE801019L (en) 1980-11-18
AU5835180A (en) 1980-11-20
IE49988B1 (en) 1986-01-22
JPH0144684B2 (Direct) 1989-09-29
HU178867B (en) 1982-07-28
EP0019282B1 (en) 1983-01-12
JPS55154917A (en) 1980-12-02
PH15265A (en) 1982-11-02
AU529764B2 (en) 1983-06-16
NZ193695A (en) 1984-05-31
ZA802916B (en) 1981-12-30
US4237140A (en) 1980-12-02
CA1139671A (en) 1983-01-18
EP0019282A1 (en) 1980-11-26
IL60095A0 (en) 1980-07-31

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