IL59131A - Pyridoindole derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
Pyridoindole derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL59131A IL59131A IL59131A IL5913180A IL59131A IL 59131 A IL59131 A IL 59131A IL 59131 A IL59131 A IL 59131A IL 5913180 A IL5913180 A IL 5913180A IL 59131 A IL59131 A IL 59131A
- Authority
- IL
- Israel
- Prior art keywords
- alk
- compounds
- cooalk
- preparation
- pharmaceutical compositions
- Prior art date
Links
- IVCGJOSPVGENCT-UHFFFAOYSA-N 1h-pyrrolo[2,3-f]quinoline Chemical class N1=CC=CC2=C(NC=C3)C3=CC=C21 IVCGJOSPVGENCT-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- APJYDQYYACXCRM-UHFFFAOYSA-N tryptamine Chemical compound C1=CC=C2C(CCN)=CNC2=C1 APJYDQYYACXCRM-UHFFFAOYSA-N 0.000 abstract 2
- 206010002660 Anoxia Diseases 0.000 abstract 1
- 241000976983 Anoxia Species 0.000 abstract 1
- 206010021143 Hypoxia Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000007953 anoxia Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- JDXYSCUOABNLIR-UHFFFAOYSA-N diethyl 2-oxobutanedioate Chemical compound CCOC(=O)CC(=O)C(=O)OCC JDXYSCUOABNLIR-UHFFFAOYSA-N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 230000000506 psychotropic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7910654A FR2455044A1 (fr) | 1979-04-26 | 1979-04-26 | Pyrido-indoles et leur application en therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL59131A0 IL59131A0 (en) | 1980-05-30 |
| IL59131A true IL59131A (en) | 1983-10-31 |
Family
ID=9224797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL59131A IL59131A (en) | 1979-04-26 | 1980-01-15 | Pyridoindole derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US4272539A (enExample) |
| EP (1) | EP0021857B1 (enExample) |
| JP (1) | JPS55145687A (enExample) |
| AT (1) | ATE2078T1 (enExample) |
| AU (1) | AU528231B2 (enExample) |
| CA (1) | CA1146942A (enExample) |
| DE (1) | DE3061373D1 (enExample) |
| DK (1) | DK16880A (enExample) |
| ES (2) | ES487714A0 (enExample) |
| FR (1) | FR2455044A1 (enExample) |
| GR (1) | GR74393B (enExample) |
| IL (1) | IL59131A (enExample) |
| NO (1) | NO794272L (enExample) |
| PT (1) | PT70699A (enExample) |
| ZA (1) | ZA80243B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57123180A (en) * | 1980-12-17 | 1982-07-31 | Schering Ag | 3-substituted beta-carboline, manufacture and psychotropic drug containing same |
| US4428880A (en) | 1981-05-04 | 1984-01-31 | S.A. Omnichem | Azepino[4,5-d]indole derivatives and preparation thereof |
| DE3309596A1 (de) * | 1982-08-05 | 1984-04-05 | Basf Ag, 6700 Ludwigshafen | 2-substituierte 1-(3'-aminoalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung als arzneimittel |
| DE3229215A1 (de) * | 1982-08-05 | 1984-02-09 | Basf Ag, 6700 Ludwigshafen | 1-(halogenalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung |
| US4719211A (en) * | 1984-05-01 | 1988-01-12 | American Home Products Corporation | 2,3,4,9-tetrahydro-2-heteroarylalkyl-1H-pyrido(3,4-B)indoles having antihypertensive properties |
| JP2527319B2 (ja) * | 1986-12-25 | 1996-08-21 | 川研ファインケミカル株式会社 | ７―ブロモ―β―カルボリン誘導体の製造方法 |
| DE3827727A1 (de) * | 1988-08-16 | 1990-02-22 | Boehringer Ingelheim Kg | Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion |
| FR2663935A1 (fr) * | 1990-06-27 | 1992-01-03 | Adir | Nouveaux 1,2,3,4,5,6-hexahydroazepino [4,5-b] indoles et 1,2,3,4-tetrahydrobethacarbolines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| DE4104257A1 (de) * | 1991-02-13 | 1992-08-20 | Boehringer Ingelheim Kg | Verwendung von anellierten tetrahydropyridinessigsaeurederivaten fuer die behandlung neurologischer erkrankungen |
| FR2724384B1 (fr) * | 1994-09-14 | 1999-04-16 | Cemaf | Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament |
| US5466688A (en) * | 1994-10-20 | 1995-11-14 | American Home Products Corporation | Pyrido[3,4-B]indole derivatives as serotonergic agents |
| FR2796644B1 (fr) * | 1999-07-23 | 2001-09-07 | Adir | Nouveaux derives de beta-carboline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB841225A (en) * | 1957-09-12 | 1960-07-13 | Roche Products Ltd | Novel quinolizine derivatives and process for the manufacture of same |
| GB1055203A (en) * | 1964-09-16 | 1967-01-18 | Ici Ltd | -ß-carboline derivatives, a process for their manufacture, and compositions containing them |
| US4091102A (en) * | 1975-08-22 | 1978-05-23 | Endo Laboratories, Inc. | Anti-depressant trans-hexahydropyrido[3,4-b]indoles |
| EP0008249B1 (fr) * | 1978-07-28 | 1981-08-26 | Synthelabo | Dérivés de fluorènes et fluoranthènes, leur procédé de préparation et leur application en thérapeutique |
| US4220774A (en) * | 1978-10-26 | 1980-09-02 | Omnium Chimique | Vincadifformine synthesis process |
-
1979
- 1979-04-26 FR FR7910654A patent/FR2455044A1/fr active Granted
- 1979-12-27 NO NO794272A patent/NO794272L/no unknown
-
1980
- 1980-01-14 JP JP300480A patent/JPS55145687A/ja active Pending
- 1980-01-15 DK DK16880A patent/DK16880A/da not_active Application Discontinuation
- 1980-01-15 GR GR60962A patent/GR74393B/el unknown
- 1980-01-15 AT AT80400051T patent/ATE2078T1/de not_active IP Right Cessation
- 1980-01-15 CA CA000343697A patent/CA1146942A/en not_active Expired
- 1980-01-15 DE DE8080400051T patent/DE3061373D1/de not_active Expired
- 1980-01-15 AU AU54631/80A patent/AU528231B2/en not_active Ceased
- 1980-01-15 US US06/112,212 patent/US4272539A/en not_active Expired - Lifetime
- 1980-01-15 ES ES487714A patent/ES487714A0/es active Granted
- 1980-01-15 ZA ZA00800243A patent/ZA80243B/xx unknown
- 1980-01-15 IL IL59131A patent/IL59131A/xx unknown
- 1980-01-15 PT PT70699A patent/PT70699A/pt unknown
- 1980-01-15 EP EP80400051A patent/EP0021857B1/fr not_active Expired
- 1980-08-14 ES ES494263A patent/ES494263A0/es active Granted
- 1980-09-04 US US06/184,070 patent/US4336256A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES8102124A1 (es) | 1980-12-16 |
| ATE2078T1 (de) | 1983-01-15 |
| ES8105733A1 (es) | 1981-06-16 |
| US4272539A (en) | 1981-06-09 |
| CA1146942A (en) | 1983-05-24 |
| AU5463180A (en) | 1980-10-30 |
| FR2455044A1 (fr) | 1980-11-21 |
| ES494263A0 (es) | 1981-06-16 |
| ZA80243B (en) | 1980-12-31 |
| DK16880A (da) | 1980-10-27 |
| GR74393B (enExample) | 1984-06-28 |
| PT70699A (fr) | 1980-02-01 |
| EP0021857B1 (fr) | 1982-12-22 |
| AU528231B2 (en) | 1983-04-21 |
| DE3061373D1 (en) | 1983-01-27 |
| JPS55145687A (en) | 1980-11-13 |
| FR2455044B1 (enExample) | 1982-05-21 |
| EP0021857A1 (fr) | 1981-01-07 |
| ES487714A0 (es) | 1980-12-16 |
| IL59131A0 (en) | 1980-05-30 |
| NO794272L (no) | 1980-10-28 |
| US4336256A (en) | 1982-06-22 |
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