IL56989A0 - 4,6-dihalo steroids of the pregnane series their preparation and pharmaceutical compositions containing them - Google Patents

4,6-dihalo steroids of the pregnane series their preparation and pharmaceutical compositions containing them

Info

Publication number
IL56989A0
IL56989A0 IL56989A IL5698979A IL56989A0 IL 56989 A0 IL56989 A0 IL 56989A0 IL 56989 A IL56989 A IL 56989A IL 5698979 A IL5698979 A IL 5698979A IL 56989 A0 IL56989 A0 IL 56989A0
Authority
IL
Israel
Prior art keywords
dihalo
steroids
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL56989A
Other languages
English (en)
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of IL56989A0 publication Critical patent/IL56989A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/0026Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
IL56989A 1978-04-05 1979-04-02 4,6-dihalo steroids of the pregnane series their preparation and pharmaceutical compositions containing them IL56989A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89364178A 1978-04-05 1978-04-05

Publications (1)

Publication Number Publication Date
IL56989A0 true IL56989A0 (en) 1979-07-25

Family

ID=25401847

Family Applications (1)

Application Number Title Priority Date Filing Date
IL56989A IL56989A0 (en) 1978-04-05 1979-04-02 4,6-dihalo steroids of the pregnane series their preparation and pharmaceutical compositions containing them

Country Status (16)

Country Link
EP (1) EP0004766A3 (es)
JP (1) JPS54135762A (es)
AR (1) AR224124A1 (es)
AT (1) ATA251679A (es)
AU (1) AU4575379A (es)
CS (1) CS209915B2 (es)
DK (1) DK136379A (es)
ES (1) ES479269A1 (es)
FI (1) FI791080A (es)
GR (1) GR66483B (es)
IL (1) IL56989A0 (es)
IT (1) IT7967708A0 (es)
NO (1) NO791143L (es)
PL (1) PL214677A1 (es)
PT (1) PT69410A (es)
ZA (1) ZA791637B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4340538A (en) * 1980-07-21 1982-07-20 The Upjohn Company Process for producing 6α-fluoro-Δ1,4 -3-keto steroids
WO2012123482A2 (en) * 2011-03-15 2012-09-20 Chiesi Farmaceutici S.P.A. Isoxazolidine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125591A (en) * 1964-03-17 Derivatives thereof
FR1273890A (fr) * 1960-05-14 1961-10-20 Chimiotherapie Lab Franc Procédé de préparation de stéroïdes 21-bromés
US3169131A (en) * 1963-03-29 1965-02-09 Upjohn Co Process for the preparation of 4-fluorohydrocortisone, 21-acylates and 16-substituted derivatives thereof, and intermediates produced in the preparation thereof

Also Published As

Publication number Publication date
IT7967708A0 (it) 1979-04-04
PT69410A (fr) 1979-04-01
EP0004766A3 (en) 1979-10-31
ATA251679A (de) 1982-04-15
EP0004766A2 (en) 1979-10-17
ES479269A1 (es) 1980-01-16
JPS54135762A (en) 1979-10-22
GR66483B (es) 1981-03-24
DK136379A (da) 1979-10-06
ZA791637B (en) 1980-11-26
PL214677A1 (es) 1980-01-02
FI791080A (fi) 1979-10-06
NO791143L (no) 1979-10-08
AU4575379A (en) 1979-10-11
AR224124A1 (es) 1981-10-30
CS209915B2 (en) 1981-12-31

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