IL56494A - 17 alpha-alkoxyalkoxy steroids of the pregnane series,their preparation and pharmaceutical compositions containing them - Google Patents

17 alpha-alkoxyalkoxy steroids of the pregnane series,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL56494A
IL56494A IL56494A IL5649479A IL56494A IL 56494 A IL56494 A IL 56494A IL 56494 A IL56494 A IL 56494A IL 5649479 A IL5649479 A IL 5649479A IL 56494 A IL56494 A IL 56494A
Authority
IL
Israel
Prior art keywords
alkoxyalkoxy
steroids
alpha
preparation
pharmaceutical compositions
Prior art date
Application number
IL56494A
Other languages
English (en)
Other versions
IL56494A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19782803661 external-priority patent/DE2803661A1/de
Priority claimed from DE19782855465 external-priority patent/DE2855465A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL56494A0 publication Critical patent/IL56494A0/xx
Publication of IL56494A publication Critical patent/IL56494A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0084—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkylene group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL56494A 1978-01-25 1979-01-25 17 alpha-alkoxyalkoxy steroids of the pregnane series,their preparation and pharmaceutical compositions containing them IL56494A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782803661 DE2803661A1 (de) 1978-01-25 1978-01-25 Neue in 17-position substituierte 11beta-hydroxysteroide der pregnanreihe, ihre herstellung und verwendung
DE19782855465 DE2855465A1 (de) 1978-12-19 1978-12-19 Neue kortikoide, verfahren zu ihrer herstellung, ihre verwendung und diese kortikoide enthaltende pharmazeutische praeparate

Publications (2)

Publication Number Publication Date
IL56494A0 IL56494A0 (en) 1979-03-12
IL56494A true IL56494A (en) 1983-02-23

Family

ID=25773724

Family Applications (1)

Application Number Title Priority Date Filing Date
IL56494A IL56494A (en) 1978-01-25 1979-01-25 17 alpha-alkoxyalkoxy steroids of the pregnane series,their preparation and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US4207316A (ru)
EP (1) EP0003341B1 (ru)
AU (1) AU529292B2 (ru)
BG (3) BG33736A3 (ru)
CS (1) CS207753B2 (ru)
DD (2) DD141523A5 (ru)
DE (1) DE2967070D1 (ru)
DK (1) DK28779A (ru)
EG (1) EG14273A (ru)
ES (1) ES477162A1 (ru)
FI (1) FI66023C (ru)
FR (1) FR2422689A1 (ru)
GB (1) GB2014150B (ru)
IE (1) IE47729B1 (ru)
IL (1) IL56494A (ru)
NO (1) NO154583C (ru)
NZ (1) NZ189460A (ru)
PH (1) PH18164A (ru)
PT (1) PT69126A (ru)
RO (2) RO81116A (ru)
SU (6) SU876059A3 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2952003A1 (de) * 1979-12-21 1981-07-02 Schering Ag Berlin Und Bergkamen, 1000 Berlin Neue kortikoid-17-thioacetale, ihre herstellung und verwendung
DE3038855A1 (de) * 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue d-homo-kortikoide, ihre herstellung und verwendung
KR960700266A (ko) * 1993-01-08 1996-01-19 클래스 빌헬름슨 신규 결장- 또는 회장-특이성 스테로이드 유도체(Novel Colon-or lleum-Specific Steroid Derivatives)
US5502222A (en) * 1994-06-01 1996-03-26 Schering Corporation Process for preparing delta 9,11 and 21-chloro corticosteroids
US8729108B2 (en) * 2008-06-17 2014-05-20 Christopher J Dannaker Waterborne topical compositions for the delivery of active ingredients such as azelaic acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6682287D0 (pt) * 1965-08-30 1973-12-04 Merck & Co Inc Processo para preparar 17-alcoxi-progesteronas
NL6605514A (ru) * 1966-04-25 1967-10-26
US3453297A (en) * 1968-07-24 1969-07-01 Merck & Co Inc 17alpha-lower alkoxy-pregna-4,6-diene-3,20-dione steroids

Also Published As

Publication number Publication date
NO154583C (no) 1986-11-05
ES477162A1 (es) 1979-07-01
NO154583B (no) 1986-07-28
EG14273A (en) 1984-06-30
DK28779A (da) 1979-07-26
IL56494A0 (en) 1979-03-12
EP0003341A3 (en) 1979-08-22
IE47729B1 (en) 1984-05-30
DE2967070D1 (en) 1984-08-02
GB2014150A (en) 1979-08-22
PH18164A (en) 1985-04-09
AU4365779A (en) 1979-08-02
RO81116B (ro) 1983-05-30
RO81116A (ro) 1983-06-01
FI790240A (fi) 1979-07-26
CS207753B2 (en) 1981-08-31
GB2014150B (en) 1982-11-24
DD141523A5 (de) 1980-05-07
SU876059A3 (ru) 1981-10-23
SU927123A3 (ru) 1982-05-07
PT69126A (de) 1979-02-01
FI66023C (fi) 1984-08-10
FR2422689A1 (fr) 1979-11-09
DD150749A5 (de) 1981-09-16
IE790134L (en) 1979-07-25
FI66023B (fi) 1984-04-30
BG33737A3 (en) 1983-04-15
BG33736A3 (en) 1983-04-15
NO790229L (no) 1979-07-26
EP0003341A2 (de) 1979-08-08
SU876060A3 (ru) 1981-10-23
EP0003341B1 (de) 1984-06-27
US4207316A (en) 1980-06-10
NZ189460A (en) 1981-11-19
SU890979A3 (ru) 1981-12-15
AU529292B2 (en) 1983-06-02
BG33738A3 (en) 1983-04-15
SU880253A3 (ru) 1981-11-07
SU1103797A3 (ru) 1984-07-15
RO76163A (ro) 1981-08-17

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