IL52227A - Process for the preparation of 10,19-dihydro-vitamin d derivatives and some novel 10,19-dihydro-1alpha-hydroxy and 1 alpha,25-dihydroxy-vitamin d3 compounds and pharmaceutical compositions containing them - Google Patents

Process for the preparation of 10,19-dihydro-vitamin d derivatives and some novel 10,19-dihydro-1alpha-hydroxy and 1 alpha,25-dihydroxy-vitamin d3 compounds and pharmaceutical compositions containing them

Info

Publication number
IL52227A
IL52227A IL52227A IL5222777A IL52227A IL 52227 A IL52227 A IL 52227A IL 52227 A IL52227 A IL 52227A IL 5222777 A IL5222777 A IL 5222777A IL 52227 A IL52227 A IL 52227A
Authority
IL
Israel
Prior art keywords
dihydro
vitamin
1alpha
dihydroxy
alpha
Prior art date
Application number
IL52227A
Other languages
English (en)
Other versions
IL52227A0 (en
Original Assignee
Res Inst Medicine Chem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Inst Medicine Chem filed Critical Res Inst Medicine Chem
Publication of IL52227A0 publication Critical patent/IL52227A0/xx
Publication of IL52227A publication Critical patent/IL52227A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14All rings being cycloaliphatic
    • C07C2602/24All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL52227A 1976-06-03 1977-06-02 Process for the preparation of 10,19-dihydro-vitamin d derivatives and some novel 10,19-dihydro-1alpha-hydroxy and 1 alpha,25-dihydroxy-vitamin d3 compounds and pharmaceutical compositions containing them IL52227A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB23036/76A GB1583749A (en) 1976-06-03 1976-06-03 Vitamin d derivatives

Publications (2)

Publication Number Publication Date
IL52227A0 IL52227A0 (en) 1977-08-31
IL52227A true IL52227A (en) 1981-05-20

Family

ID=10189072

Family Applications (1)

Application Number Title Priority Date Filing Date
IL52227A IL52227A (en) 1976-06-03 1977-06-02 Process for the preparation of 10,19-dihydro-vitamin d derivatives and some novel 10,19-dihydro-1alpha-hydroxy and 1 alpha,25-dihydroxy-vitamin d3 compounds and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US4159326A (es)
JP (1) JPS5315356A (es)
AU (1) AU517020B2 (es)
BE (1) BE855326A (es)
CA (1) CA1111435A (es)
CH (1) CH629768A5 (es)
DE (1) DE2724994A1 (es)
DK (1) DK243477A (es)
ES (1) ES459413A1 (es)
FR (2) FR2353529A1 (es)
GB (1) GB1583749A (es)
IE (1) IE45627B1 (es)
IL (1) IL52227A (es)
IN (1) IN156431B (es)
LU (1) LU77468A1 (es)
MX (1) MX4820E (es)
NL (1) NL7706056A (es)
NO (1) NO771946L (es)
NZ (1) NZ184288A (es)
SE (1) SE7706469L (es)
ZA (1) ZA773308B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588716A (en) * 1984-05-04 1986-05-13 Wisconsin Alumni Research Foundation Method for treating metabolic bone disease in mammals
US5789397A (en) * 1991-01-08 1998-08-04 Bone Care International, Inc. Methods for preparation and use of 1A,24(S)-dihydroxy vitamin D2
US6251883B1 (en) 1991-01-08 2001-06-26 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxy vitamin D2
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
US6538037B2 (en) 1991-01-08 2003-03-25 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-dihydroxyvitamin D2
US6166000A (en) * 1991-01-08 2000-12-26 Bone Care International, Inc. Methods for preparation and use of 1α,24(S)-Dihydroxy vitamin . D.sub2
AU1247592A (en) 1991-01-08 1992-08-17 Lunar Corporation Methods for preparation and use of 1alpha,24-dihydroxy vitamin d2
DE69325253T2 (de) * 1992-08-28 1999-12-02 Bone Care International Inc., Madison 1alpha,24(s)-dihydroxy vitamin d2, seine synthese und verwendung
AU7719894A (en) * 1993-09-03 1995-03-22 Smithkline Beecham Corporation Stabilized tablet formulation
DE29506819U1 (de) * 1995-04-28 1995-07-13 Groz-Beckert KG, 72458 Albstadt Barre mit Modulen für Tuftingwerkzeuge (II)
US6362350B1 (en) 1999-07-01 2002-03-26 Wisconsin Alumni Research Foundation Crystalline 1α, 24(S)-dihydroxyvitamin D2 and method of purification thereof
US20060003950A1 (en) * 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents
US7094775B2 (en) * 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3049553A (en) * 1962-08-14 Process for the production of the reduc-
US2942009A (en) * 1956-02-14 1960-06-21 Philips Corp Method of reducing unsaturated compounds with an alkaline or alkalineearth metal in liquid ammonia
US3607888A (en) * 1969-08-07 1971-09-21 Wisconsin Alumni Res Found 25-hydroxytachysterol3 25-hydroxydihydrotachysterol3 and methods for preparing same
US3725489A (en) * 1969-10-02 1973-04-03 Allied Chem Hydrogenation of alkenes employing an organometallic hydrogenation catalyst
US3697559A (en) * 1971-02-25 1972-10-10 Wisconsin Alumni Res Found 1,25-dihydroxycholecalciferol
US3901928A (en) * 1973-01-10 1975-08-26 Robert Henry Hesse 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds
JPS5119752A (en) * 1974-08-07 1976-02-17 Masayuki Ishikawa 1 arufua* 2 arufuaa jihidorokishikorekarushifuerooruno seiho

Also Published As

Publication number Publication date
FR2429783B1 (es) 1981-05-08
AU517020B2 (en) 1981-07-02
CH629768A5 (de) 1982-05-14
BE855326A (fr) 1977-12-02
IE45627L (en) 1977-12-03
DE2724994A1 (de) 1977-12-15
DK243477A (da) 1977-12-04
SE7706469L (sv) 1977-12-04
ZA773308B (en) 1978-07-26
JPS625903B2 (es) 1987-02-07
NO771946L (no) 1977-12-06
LU77468A1 (es) 1977-09-19
FR2353529A1 (fr) 1977-12-30
FR2429783A1 (fr) 1980-01-25
GB1583749A (en) 1981-02-04
NL7706056A (nl) 1977-12-06
FR2353529B1 (es) 1980-04-25
US4159326A (en) 1979-06-26
ES459413A1 (es) 1978-04-01
JPS5315356A (en) 1978-02-13
IN156431B (es) 1985-08-03
AU2574977A (en) 1978-12-07
IL52227A0 (en) 1977-08-31
MX4820E (es) 1982-10-20
NZ184288A (en) 1980-08-26
CA1111435A (en) 1981-10-27
IE45627B1 (en) 1982-10-20

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