IL49702A - Thieno(2,3-c)pyridine derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

Thieno(2,3-c)pyridine derivatives, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL49702A
IL49702A IL49702A IL4970276A IL49702A IL 49702 A IL49702 A IL 49702A IL 49702 A IL49702 A IL 49702A IL 4970276 A IL4970276 A IL 4970276A IL 49702 A IL49702 A IL 49702A
Authority
IL
Israel
Prior art keywords
thieno
preparation
pharmaceutical compositions
compositions containing
pyridine derivatives
Prior art date
Application number
IL49702A
Other languages
English (en)
Other versions
IL49702A0 (en
Original Assignee
Parcor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parcor filed Critical Parcor
Publication of IL49702A0 publication Critical patent/IL49702A0/xx
Publication of IL49702A publication Critical patent/IL49702A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
IL49702A 1975-06-27 1976-06-01 Thieno(2,3-c)pyridine derivatives, their preparation and pharmaceutical compositions containing them IL49702A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7520241A FR2315274A1 (fr) 1975-06-27 1975-06-27 Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications

Publications (2)

Publication Number Publication Date
IL49702A0 IL49702A0 (en) 1976-08-31
IL49702A true IL49702A (en) 1979-01-31

Family

ID=9157178

Family Applications (1)

Application Number Title Priority Date Filing Date
IL49702A IL49702A (en) 1975-06-27 1976-06-01 Thieno(2,3-c)pyridine derivatives, their preparation and pharmaceutical compositions containing them

Country Status (26)

Country Link
US (1) US4075340A (fr)
JP (1) JPS607633B2 (fr)
AR (1) AR211777A1 (fr)
AT (1) AT347950B (fr)
BE (1) BE843402A (fr)
CA (1) CA1071635A (fr)
CH (1) CH596169A5 (fr)
DD (1) DD125080A5 (fr)
DE (1) DE2628045A1 (fr)
DK (1) DK279976A (fr)
ES (1) ES449191A1 (fr)
FR (1) FR2315274A1 (fr)
GB (1) GB1492239A (fr)
GR (1) GR60042B (fr)
HU (1) HU172697B (fr)
IE (1) IE43915B1 (fr)
IL (1) IL49702A (fr)
LU (1) LU75230A1 (fr)
MX (1) MX3565E (fr)
NL (1) NL183032C (fr)
PL (1) PL105962B1 (fr)
PT (1) PT65271B (fr)
SE (1) SE421698B (fr)
SU (1) SU628820A3 (fr)
YU (1) YU39480B (fr)
ZA (1) ZA763270B (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4127580A (en) * 1975-02-07 1978-11-28 Parcor Process for the preparation of thieno-pyridine derivatives
FR2395271A1 (fr) * 1977-06-21 1979-01-19 Parcor Procede de preparation de thieno (2,3-c) et thieno (3,2-c) pyridines
GB2038625B (en) * 1978-12-29 1983-01-12 Parcor Therapeutic composition having an antithrombotic and antiblood-platelet-aggregating activity
US4749692A (en) * 1977-06-22 1988-06-07 Sanofi, S.A. Therapeutic compositions having anti-thrombotic and anti-blood-platelet-aggregating activity
FR2397417A1 (fr) * 1977-07-12 1979-02-09 Parcor Procede de preparation de derives de la thienopyridine
AT368504B (de) * 1977-10-15 1982-10-25 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer 4-phenyl-thieno- (2,3-c)-piperidine
US4321266A (en) * 1980-10-06 1982-03-23 Sanofi 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-C] pyridine
FR2508453A1 (fr) * 1981-06-30 1982-12-31 Sanofi Sa Procede de preparation de derives des (thienyl-2)- et thienyl-3)-2 ethylamines et produits ainsi obtenus
US4547514A (en) * 1983-12-05 1985-10-15 A. H. Robins Company, Incorporated Aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and carbothioamides having antiarrhythmic activity
DE3736664A1 (de) * 1987-10-29 1989-05-11 Boehringer Ingelheim Kg Tetrahydro-furo- und -thieno(2,3-c)pyridine, ihre verwendung als arzneimittel und verfahren zu ihrer herstellung
US5294621A (en) * 1992-10-07 1994-03-15 Ortho Pharmaceutical Corporation Thieno tetrahydropyridines useful as class III antiarrhythmic agents
WO2000000472A1 (fr) * 1998-06-30 2000-01-06 Du Pont Pharmaceuticals Company Antagonistes du recepteur 5-ht¿7?
US6090797A (en) * 1998-09-02 2000-07-18 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno(2,3-C)pyridine derivatives
AU5154699A (en) * 1998-09-02 2000-03-27 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno(2,3-c)pyridine derivatives
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
CA2476896A1 (fr) * 2002-02-26 2003-09-04 North Shore-Long Island Jewish Research Institute Inhibition de la production d'une cytokine inflammatoire par la stimulation de recepteurs muscariniques cerebraux
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
WO2005092308A2 (fr) 2004-03-25 2005-10-06 The Feinstein Institute For Medical Research Garrot neural
EP2298410B1 (fr) 2004-12-27 2013-10-09 The Feinstein Institute for Medical Research Traitement des troubles inflammatoires par la stimulation électrique du nerf vague
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
WO2009029614A1 (fr) 2007-08-27 2009-03-05 The Feinstein Institute For Medical Research Dispositifs et procédés permettant d'inhiber l'activation de granulocytes par stimulation neurale
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
WO2009146030A1 (fr) 2008-03-31 2009-12-03 The Feinstein Institute For Medical Research Méthodes et systèmes de réduction d’une inflammation par neuromodulation de l’activité des lymphocytes t
EP2355893B1 (fr) 2008-11-18 2013-12-25 Setpoint Medical Corporation Dispositifs permettant d'optimiser la pose d'une électrode pour stimulation anti-inflammatoire
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
EP2440284B1 (fr) 2009-06-09 2018-09-12 Setpoint Medical Corporation Manchon pour nerf muni d'une poche pour stimulateur sans fil
WO2014169145A1 (fr) 2013-04-10 2014-10-16 Setpoint Medical Corporation Stimulation de nerf vague en boucle fermée
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
EP3636314B1 (fr) 2009-12-23 2021-09-08 Setpoint Medical Corporation Dispositifs et systèmes de stimulation neuronale pour le traitement de l'inflammation chronique
EP2707094B1 (fr) 2011-05-09 2016-02-03 Setpoint Medical Corporation Activation d'impulsions uniques de la voie anti-inflammatoire cholinergique pour traiter l'inflammation chronique
AU2013235487B2 (en) 2012-03-23 2017-09-07 Memorial Sloan-Kettering Cancer Center Treatment of pancreatic and related cancers with 5-acyl-6,7-dihydrothieno[3,2-c]pyridines
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
US10011585B2 (en) 2014-07-28 2018-07-03 Merck Sharp & Dohme Corp. Factor XIa inhibitors
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
WO2016126807A1 (fr) 2015-02-03 2016-08-11 Setpoint Medical Corporation Appareil et procédé de rappel, d'incitation ou d'alerte d'un patient ayant un stimulateur implanté
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
US10695569B2 (en) 2016-01-20 2020-06-30 Setpoint Medical Corporation Control of vagal stimulation
EP3405255A4 (fr) 2016-01-20 2019-10-16 Setpoint Medical Corporation Microstimulateurs implantables et systèmes de recharge par induction
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
WO2019036470A1 (fr) 2017-08-14 2019-02-21 Setpoint Medical Corporation Test de dépistage pour stimulation du nerf vague
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
KR20230012585A (ko) 2020-05-21 2023-01-26 더 파인스타인 인스티튜츠 포 메디칼 리서치 미주 신경 자극을 위한 시스템들 및 방법들

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2215948B1 (fr) * 1973-02-01 1976-05-14 Centre Etd Ind Pharma

Also Published As

Publication number Publication date
PL105962B1 (pl) 1979-11-30
AT347950B (de) 1979-01-25
NL183032C (nl) 1988-07-01
ATA461776A (de) 1978-06-15
JPS525793A (en) 1977-01-17
IE43915B1 (en) 1981-07-01
FR2315274B1 (fr) 1979-08-10
ZA763270B (en) 1977-05-25
IE43915L (en) 1976-12-27
FR2315274A1 (fr) 1977-01-21
GR60042B (en) 1978-04-01
ES449191A1 (es) 1977-12-01
DD125080A5 (fr) 1977-03-30
PT65271B (fr) 1977-12-10
PT65271A (fr) 1976-07-01
BE843402A (fr) 1976-12-27
GB1492239A (en) 1977-11-16
SE421698B (sv) 1982-01-25
DE2628045A1 (de) 1977-01-20
AR211777A1 (es) 1978-03-15
AU1537576A (en) 1978-01-05
JPS607633B2 (ja) 1985-02-26
CA1071635A (fr) 1980-02-12
SE7607201L (sv) 1976-12-28
SU628820A3 (ru) 1978-10-15
MX3565E (es) 1981-03-13
NL7606574A (nl) 1976-12-29
LU75230A1 (fr) 1977-02-18
HU172697B (hu) 1978-11-28
CH596169A5 (fr) 1978-02-28
NL183032B (nl) 1988-02-01
DK279976A (da) 1976-12-28
IL49702A0 (en) 1976-08-31
US4075340A (en) 1978-02-21
YU39480B (en) 1984-12-31
YU146276A (en) 1982-05-31

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