IL47975A - 4-oxo-and 4-thioxo-hexahydro-4h-pyrazino(2,1- )isoquinoline derivatives and preparation thereof - Google Patents

4-oxo-and 4-thioxo-hexahydro-4h-pyrazino(2,1- )isoquinoline derivatives and preparation thereof

Info

Publication number
IL47975A
IL47975A IL47975A IL4797575A IL47975A IL 47975 A IL47975 A IL 47975A IL 47975 A IL47975 A IL 47975A IL 4797575 A IL4797575 A IL 4797575A IL 47975 A IL47975 A IL 47975A
Authority
IL
Israel
Prior art keywords
pyrazino
thioxo
hexahydro
oxo
preparation
Prior art date
Application number
IL47975A
Other languages
English (en)
Other versions
IL47975A0 (en
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of IL47975A0 publication Critical patent/IL47975A0/xx
Publication of IL47975A publication Critical patent/IL47975A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IL47975A 1974-08-28 1975-08-21 4-oxo-and 4-thioxo-hexahydro-4h-pyrazino(2,1- )isoquinoline derivatives and preparation thereof IL47975A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2441261A DE2441261A1 (de) 1974-08-28 1974-08-28 Ringsubstituierte pyrazino-isochinolin-derivat und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
IL47975A0 IL47975A0 (en) 1975-11-25
IL47975A true IL47975A (en) 1980-05-30

Family

ID=5924323

Family Applications (1)

Application Number Title Priority Date Filing Date
IL47975A IL47975A (en) 1974-08-28 1975-08-21 4-oxo-and 4-thioxo-hexahydro-4h-pyrazino(2,1- )isoquinoline derivatives and preparation thereof

Country Status (22)

Country Link
US (1) US4051243A (enEXAMPLES)
JP (1) JPS5168595A (enEXAMPLES)
AT (1) AT350055B (enEXAMPLES)
BE (1) BE832735A (enEXAMPLES)
CH (3) CH617934A5 (enEXAMPLES)
DD (1) DD121789A5 (enEXAMPLES)
DE (1) DE2441261A1 (enEXAMPLES)
DK (1) DK386175A (enEXAMPLES)
EG (1) EG12384A (enEXAMPLES)
ES (1) ES440509A1 (enEXAMPLES)
FI (1) FI752411A7 (enEXAMPLES)
FR (1) FR2282891A1 (enEXAMPLES)
GB (1) GB1479235A (enEXAMPLES)
IE (1) IE42218B1 (enEXAMPLES)
IL (1) IL47975A (enEXAMPLES)
LU (1) LU73263A1 (enEXAMPLES)
NL (1) NL7510173A (enEXAMPLES)
NO (1) NO752939L (enEXAMPLES)
OA (1) OA05094A (enEXAMPLES)
PH (1) PH12677A (enEXAMPLES)
SE (1) SE7509473L (enEXAMPLES)
ZA (1) ZA755480B (enEXAMPLES)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141978A (en) * 1973-12-17 1979-02-27 Merck Patent Gesellschaft Mit Beschrankter Haftung 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4196291A (en) * 1973-12-17 1980-04-01 Merck Patent Gesellschaft Mit Beschraenkter Haftung 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
US4120961A (en) * 1974-08-28 1978-10-17 E. Merck Ring substituted pyrazino-isoquinoline derivatives and their preparation
FR2520740A1 (fr) * 1982-01-29 1983-08-05 Sanofi Sa Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires
US4517187A (en) * 1982-10-18 1985-05-14 Pennwalt Corporation 1,3,4,6,7-11b-Hexahydro-7-phenyl-2H-pyrazino[2,1-a]isoquinolines methods of preparation, and use as antidepressants
EP0134984B1 (en) * 1983-07-16 1988-07-13 Beecham Group Plc Benzazepine and benzoxazepine derivatives
US4772705A (en) * 1985-07-25 1988-09-20 Pennwalt Corporation Processes for the preparation of trans 1,3,4,6,7,11b-hexahydro-7-aryl-2H-pyrazinol[2,1-a]isoquinolines
US20040131560A1 (en) * 2002-10-04 2004-07-08 The Procter & Gamble Company Oral compositions and use thereof
UA95093C2 (uk) * 2005-12-07 2011-07-11 Нікомед Фарма Ас Спосіб одержання кальцієвмісної сполуки
TWI519508B (zh) * 2007-06-12 2016-02-01 Achaogen Inc 抗菌劑
CN101691367B (zh) * 2009-08-31 2013-07-24 中国人民解放军第二军医大学 具有抗真菌活性的哌嗪并[2,1-a]异喹啉类化合物或其盐类
WO2021041539A2 (en) * 2019-08-28 2021-03-04 Ferro Therapeutics, Inc. Compounds and methods of use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2362539C2 (de) * 1973-12-17 1986-05-07 Merck Patent Gmbh, 6100 Darmstadt 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
FR2282891B1 (enEXAMPLES) 1980-03-28
ATA663375A (de) 1978-10-15
DK386175A (da) 1976-02-29
FR2282891A1 (fr) 1976-03-26
PH12677A (en) 1979-07-11
OA05094A (fr) 1981-01-31
BE832735A (nl) 1976-02-25
GB1479235A (en) 1977-07-06
CH617934A5 (enEXAMPLES) 1980-06-30
IE42218B1 (en) 1980-07-02
SE7509473L (sv) 1976-03-01
ES440509A1 (es) 1977-06-01
AT350055B (de) 1979-05-10
JPS5168595A (en) 1976-06-14
AU8410675A (en) 1977-02-24
CH623584A5 (enEXAMPLES) 1981-06-15
US4051243A (en) 1977-09-27
CH624113A5 (enEXAMPLES) 1981-07-15
DE2441261A1 (de) 1976-03-18
LU73263A1 (enEXAMPLES) 1977-04-15
IE42218L (en) 1976-02-28
EG12384A (en) 1980-03-31
ZA755480B (en) 1976-07-28
FI752411A7 (enEXAMPLES) 1976-02-29
IL47975A0 (en) 1975-11-25
NL7510173A (nl) 1976-03-02
NO752939L (enEXAMPLES) 1976-03-02
DD121789A5 (enEXAMPLES) 1976-08-20

Similar Documents

Publication Publication Date Title
ZA755614B (en) 1,3,4-trisubstituted-4-arylpiperidines and their preparation
IL47975A (en) 4-oxo-and 4-thioxo-hexahydro-4h-pyrazino(2,1- )isoquinoline derivatives and preparation thereof
ZA755929B (en) Aminobenzazocines and preparation thereof
ZA754975B (en) 7-methoxy-6-thiatetracyclines and their preparation
ZA756481B (en) 4-methylthio-2-trifluoromethyl methane-sulfonanilide and derivatives thereof
JPS5262399A (en) Polyamideterpolymer and preparation thereof
JPS51138609A (en) 12222tetrafluoroethyll fluoromethilether and its preparation
ZA75703B (en) New phenoxy-alkyl-carboxylic acid derivatives and the preparation thereof
IL58505A0 (en) 16,16-disubstituted androst-5-ene derivatives and their preparation
GB1519050A (en) Indolo-quinolizine derivatives and a process for the preparation thereof
JPS5212158A (en) Epoxyandrostane and preparation thereof
ZA757673B (en) Phenylpyridazines and the preparation thereof
IL47335A0 (en) Hexahydro-diazepino-indole derivatives and the preparation thereof
JPS5251364A (en) Thiazolizine derivatives and preparation thereof
GB1521487A (en) 1,2,3,4-tetrahydroisoquinolines and the preparation thereof
ZA763622B (en) 1-acyl-1,2,3,4-tetrahydro-6-quinolinols and their preparation
ZA757458B (en) New prostenoic acid derivatives and with the preparation thereof
IL48140A0 (en) Novel 2,6-methano-3-benzazocines and their preparation
GB1488068A (en) 7alpha-alkoxy-cephalosporin derivatives and their preparation
AU8273475A (en) Isoquinoline derivatives
GB1548989A (en) Amino1,2,3,4-tetrahydrobenyo (g) isoquinoline and derivatives thereof
GB1549237A (en) 2,5-dihydrofuron derivatives and their preparation
JPS51119096A (en) Polyurethaneeelastmer and preparation thereof
ZA752472B (en) 3,4-dicarboxycephalosporins and derivatives
ZA756355B (en) 3,7-dimethyl-3-hydroxy-6-octenenitrile and process for its preparation