IL47043A - Pharmaceutical preparations comprising crystallized insulin and amorphous des-phenylal-anine-insulin having antidiabetic activity and process for their manufacture - Google Patents
Pharmaceutical preparations comprising crystallized insulin and amorphous des-phenylal-anine-insulin having antidiabetic activity and process for their manufactureInfo
- Publication number
- IL47043A IL47043A IL47043A IL4704375A IL47043A IL 47043 A IL47043 A IL 47043A IL 47043 A IL47043 A IL 47043A IL 4704375 A IL4704375 A IL 4704375A IL 47043 A IL47043 A IL 47043A
- Authority
- IL
- Israel
- Prior art keywords
- insulin
- phenylal
- anine
- manufacture
- pharmaceutical preparations
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 3
- 229940125396 insulin Drugs 0.000 title 2
- 102000004877 Insulin Human genes 0.000 title 1
- 108090001061 Insulin Proteins 0.000 title 1
- 230000003178 anti-diabetic effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2418218A DE2418218A1 (de) | 1974-04-13 | 1974-04-13 | Neue arzneimittel-zubereitung mit antidiabetischer wirkung |
DE19742459515 DE2459515C3 (de) | 1974-12-17 | 1974-12-17 | Arzneimittelzubereitungen mit antidiabetischer Wirkung |
Publications (2)
Publication Number | Publication Date |
---|---|
IL47043A0 IL47043A0 (en) | 1975-06-25 |
IL47043A true IL47043A (en) | 1978-06-15 |
Family
ID=25766977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL47043A IL47043A (en) | 1974-04-13 | 1975-04-07 | Pharmaceutical preparations comprising crystallized insulin and amorphous des-phenylal-anine-insulin having antidiabetic activity and process for their manufacture |
Country Status (11)
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1560232A (en) * | 1977-02-01 | 1980-01-30 | Novo Industri As | Biphasic insulin preparations comprising crystalline insulin and monodesamido insulin |
DE3717370A1 (de) * | 1987-05-22 | 1988-12-01 | Hoechst Ag | Mischkristalle aus insulin und insulinderivaten, verfahren zur herstellung dieser mischkristalle, diese mischkristalle enthaltende pharmazeutische mittel und ihre verwendung zur behandlung von diabetes mellitus |
DE69627340T2 (de) | 1995-07-25 | 2004-02-05 | Novartis Ag | Transformierenden waeckstumsfaktor beta krystalle |
-
1975
- 1975-03-31 EG EG178/75A patent/EG12098A/xx active
- 1975-04-07 IL IL47043A patent/IL47043A/xx unknown
- 1975-04-07 GB GB14079/75A patent/GB1492837A/en not_active Expired
- 1975-04-08 NL NL7504165A patent/NL7504165A/xx not_active Application Discontinuation
- 1975-04-08 ES ES436398A patent/ES436398A1/es not_active Expired
- 1975-04-10 FI FI751084A patent/FI751084A7/fi not_active Application Discontinuation
- 1975-04-11 AU AU80073/75A patent/AU500430B2/en not_active Expired
- 1975-04-11 CA CA224,590A patent/CA1047919A/en not_active Expired
- 1975-04-11 LU LU72269A patent/LU72269A1/xx unknown
- 1975-04-11 IE IE832/75A patent/IE40985B1/xx unknown
- 1975-04-14 FR FR7511535A patent/FR2267116B1/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2267116B1 (enrdf_load_stackoverflow) | 1978-10-06 |
FI751084A7 (enrdf_load_stackoverflow) | 1975-10-14 |
ES436398A1 (es) | 1977-05-01 |
NL7504165A (nl) | 1975-10-15 |
GB1492837A (en) | 1977-11-23 |
IE40985B1 (en) | 1979-09-26 |
CA1047919A (en) | 1979-02-06 |
FR2267116A1 (enrdf_load_stackoverflow) | 1975-11-07 |
LU72269A1 (enrdf_load_stackoverflow) | 1977-02-03 |
IL47043A0 (en) | 1975-06-25 |
IE40985L (en) | 1975-10-13 |
AU500430B2 (en) | 1979-05-24 |
AU8007375A (en) | 1976-10-14 |
EG12098A (en) | 1980-12-31 |
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