IL44964A

IL44964A - Large capacity syringe

Info

Publication number: IL44964A
Application number: IL44964A
Authority: IL
Original assignee: Survival Technology
Priority date: 1973-09-27
Filing date: 1974-06-03
Publication date: 1977-10-31
Also published as: SE7410614L; CA1032047A; ES220443Y; JPS5060086A; DE2445535A1; GB1437595A; NL7410918A; CH583568A5; FR2245382A1; BE820501A; SE406707B; IL44964A0; AU6946874A; ES220443U; AR201235Q; AU468624B2; IT1022396B; US3895633A; FR2245382B1

Description

n na nVtan Vsra PITS LARGE CAPACITY SYRINGE ABSTRACT A syringe adapted to inject substantial amounts of medicament, said syringe comprising a syringe barrel having a necked portion at one end with a central through-bore while the other end is open and provided with a peripheral flange. A cannula assembly is fixedly fitted into the necked end of the syringe barrel, said cannula assembly including a body portion fixedly fitting into the necked portion of the syringe barrel with a cannula extending outwardly therefrom. A cylindrical needle support extends rearwardly from the body and mounts a needle within the syringe barrel . A cartridge assembly is slidably carried within the syringe barrel and includes a cylindrical cartridge body having a necked end closed by a stopper.

The open end of the cylindrical body is closed off by a plunger whereby the medicament is held between the stopper and the plunger. The necked end of the cartridge body mounts a cap having an outwardly extending sleeve sized to fit over the needle support. Interengaging means are provided on the sleeve and needle support to lock the cartridge assembly in inactivated and actuated position. A retaining clip fits over the open end of the syringe barrel to retain the cartridge assembly within said barrel. nTfiflUSSTON OF PRIOR ART The field of large syringes capable of injecting large amounts of medicament has expanded tremendously in recent years . One of the interesting prior art patents in this field is that to Miskel, U.S. patent No. 2,778,360. One of the embodiments described in the Miskel patent describes a cartridge comprising an elongated hollow glass cylinder containing a frangible membrane for separating two medicaments in the cylinder. One end of the cylinder is closed by a plunger while the other end 4s closed by a stopper held in place by a closure cap which overlies the face of the stopper flange to compress the same against the ampoule neck. The cartridge is slidably carried in a syringe casing, one of which mounts a needle unit comprising a needle holder formed as a stopped cylinder having a rearwardly extending skirt, a cylindrical portion and a reduced cylindrical forward portion which mounts a needle. A plug fits within the aforesaid cylindrical portion and mounts a stopper piercing needle. The needle holder unit with both needles is mounted in the forward end of the syringe casing whereby the closure cap will slidably fit within the rearwardly extending skirt so that the cartridge may be pushed forward in order to pierce the stopper with the cannula to allow ejection of the medicament.

The device of this invention is an improvement over the Miskel device in several ways. First of all, in Applicants' device the cannula sheath fits over the outer surface of the outer sleeve of the cannula mounting body member. This assures that any wobble produced b# the needle in the cannula body mounting member will not affect the seal.

Further, on the inside end of Applicants' needle is protected by a sleeve on a cap which is sealingly connnected over the cap of the cartridge. It should be further noted hat in Applicants1 device the cannula mounting body together with the portions which extend forwardly and rearwardly thereof is an important factor since there is no possibility of any contamination reaching the cannula or needle with such an integral construction. There are other advantages with regard to thej-psesent invention and such will become apparent in the following detailed description.

SUMMARY OF THE INVENTION There is today more than ever a great need for hyp.rodermic syringe assemblies capable of dispensing relatively large amounts of medicament, for example, in the orders of lOcc and 50cc. In addition, the unit must be economical and foolproof in use. This need immediately suggests a device having disposable cartridges and cannula needles. In addition, the syringe unit must be stowable for rather lengthy periods of time without loss of effectiveness. It is with the above in mind that the syringe assembly of this invention has been developed.

In view of the foregoing, it is an object of this invention to provide a hypodermic syringe having a substantial capacity and further having a disposable cartridge assembly and cannula assembly.

It is another object of this invention to provide a syringe comprising a holder barrel, a cannula assembly fixedly positioned in one end of the barrel and a cartridge assembly slidably mounted within the barrel for communication with the cannula.

It is a still further object to provide a syringe comprising a syringe barrel having a necked portion at one end with a central through-bore while the other end is open and provided with a peripheral flange. A cannula assembly is fixedly fitted into the necked end of the syringe barrel, said cannula assembly including a body portion fixedly fitting into the necked portion of the syringe barrel with a cannula extending outwardly therefrom. A cylindrical needle support extends rearwardly from the body and mounts a needle ■within the syringe "barrel. A cartridge assembly is slidably carried within the syringe barrel and includes a cylindrical cartridge body having a necked end closed by a stopper. The open end of the cylindrical body is closed off by a plunger whereby the medicament is held between the stopper and the plunger. The necked end of the cartridge body mounts a cap having an outwardly extending sleeve sized to fit over the needle support. Interengaging means are provided on the sleeve and needle support to lock the cartridge assembly in inactivated and actuated position. A retaining clip fits over the open end of the syringe barrel to retain the cartridge assembly within said barrel.

It is yet another object of this invention to provide as a single assembled unit the combination of a cannula assembly and a cartridge assembly wherein the unit as such is sterile and ready for assembly into a syringe barrel.

It is still another object of this invention to provide a single assembled unit as above wherein the can-nulas may be changed depending upon the particular need.

IN THE DRAWINGS Fig. 1 is a sectional view of the syringe as it appears when ready for use, with the cannula sheath still in place.

Fig. 2 is a sectional view of the syringe after the device has been actuated by pressing on the plunger to cause the cartridge assembly to move toward the cannula end whereby the stopper is pierced by the rear needle and communi Fig. 3 is an exploded view illustrating the parts of the syringe, and Fig. 4 is a sectional view of the top portion of a modification wherein a retaining member is fitted over the open end of the cylindrical cartridge body to retain the plunger within said body.

DETAILED DESCRIPTION As shown in Fig. » the syringe.10 comprises a cylindrical syringe barrel 20 which slidably carries within it a cylindrical cartridge body 30 . Plunger 40 frictionally fits within the cylindrical cartridge body 30 and has a plunger rod 50 threadedly affixed thereto. A retainer βθ clips down over the peripheral flange 22 of barrel 20 to hold the cartridge body 30 and plunger 40 within the barrel 20 . A cap 70 fits over the necked end of the cartridge body 30 and slidably receives the needle end of cannula assembly 80. A sheath 120 fits over the injection cannula 87 for safety and sterility.

More specifically3 as illustrated in Figs. 1 and 2, the syringe 10 comprises a transparent cylindrical syringe barrel 20 having an open end with the other end being formed into an axially extending necked flange 24 of a diameter less than that of the barrel. The flange 24 has internal threads 25 for purposes to be described later. The open end of the syringe barrel is provided with a peripheral flange 22.

A cartridge assembly is slidably carried within the syringe barrel 20 and comprises a cylindrical body 30 a necked portion 31 which is substantially smaller than the cartridge body to form an opening 32 aligned with the longitudinal axis of the cartridge body 30. The necked portion 31 terminates in a peripheral flange 3 . A stopper 90 closes off the opening 32, and specifically includes a disc portion 92 fitting over the entire end of the peripheral flange 3 with a sleeve portion 94 extending outwardly from the disc portion 92 and being sized to snugly fit within the necked portion 31. A retaining ring 96 fits over the stopper disc portion 92 and over and around the peripheral flange 34 to hold the stopper 90 securely in place.

A cap 70 fits over retaining ring 96 and includes a cylindrical body 72 having inwardly projecting lugs 74 which fit. over flange 34 to retain the cap 70 in position. A cap sleeve 6 extends from the cap body 72 and has a dir-ameter less than that of the body with its longitudinal axis in alignment with that of the cartridge body 30. A positioning and retaining annular bead 78 is internally formed on the sleeve 76 adjacent the end thereof.

A cannula assembly 80 is fixedly mounted in the syringe barrel 20 and comprises a threaded body portion 8l sized for threading into threads 25 of the syringe barrel flange 2 . The body portion 8l has a circular flange 82 at one end of the threaded portion which flange bears against the inner end of the syringe barrel flange 2 to firmly position the cannula body in the syringe barrel. The body portion 8l has a horizontal section 83 extending outwardly therefrom for wrench use when assembly takes place and is further formed with a central opening aligned with the extends forwardly from the body 8l coaxially with the body opening. The outer surface of the inner sleeve is provided with a slight taper in conformance with standard Luer tapers. An outer sleeve 85 also extends from the body 8l coaxially and spaced from inner sleeve 84. The inner surface of outer sleeve 85 is provided with threads 86 of the standard "Luer-Lok" type.

An injection cannular 87 with attached hub 88 and outwardly extending peripheral flange 89 is fitted over inner sleeve 84 with the flange 89 being threaded into outer sleeve threads 86. The hub 88 may be provided with peripheral flat portions to accommodate a wrench for assembly purposes. A cylindrical needle support 100 of reduced diameter extends rearwardly from the body 8l and has its longitudinal axis in alignment with that of the body. Needle support 100 mounts a needle 102 at its outer end for ultimate communication with the medicament within the cartridge cylinder 30. A peripheral bead 104 is formed on the needle support 100 adjacent the needle to frictionally engage the inner wall of the cap sleeve 76 and maintain sterility. Additionally, needle support 100 is provided with an annular recess 106 forwardly of the bead 104 and also with a peripheral shoulder 108 forwardly of the annular recess 106. The diameter of needle support 100 is sized to fit within cap sleeve 76 while annular recess 106 is adapted to be engaged by the bead 78 and later by shoulder 108 engaging bead 78.

The medicament 110 within the cylinder 30 is held therein by stopper 9° and plunger 49 which snugly fits within the cartridge cylinder 30. The plunger 40 has a surface of the cartridge cylinder 30 to provide a good seal and yet moderate friction. The exposed end of the plunger 40 is provided with an internally threaded hole adapted to threadedly receive the threaded end 52 of plunger rod 50 while the outer end of the plunger rod 50 is formed with a finger grip 54 to assist in operation of the syringe device.

The cartridge cylinder 30 and plunger 40 are retained within the syringe barrel 20 by means of retaining clip 60. As shown in Fig. 35 clip 60 has a pair of opposed wings 62 extending outwardly from disc base 64. A clip 66 extends downwardly from the end of each wing 62. As shown in Fig. lj the retaining clip 60 fits over the end of syringe barrel 20 so that the clips 66 will fit over the barrel flange 22. Further, the injection cannula 87 is protected in storage condition by means of cannula sheath 120 whose open end fits snugly over outer sleeve 85 of the cannula body 8l to maintain sterility.

The assembly and operation of the syringe device should now be obvious in view of the foregoing description^ even so a brief description follows. First of all, the cap 70 is assembled to cannula assembly 80 as illustrated in Fig. 1 with the bead 78 on sleeve 76 fitting into recess 106 on needle support 100. After this, the cap 70 is affixed to the stoppered end of cartridge body 30 by fitting same over retaining ring 96. The thus assembled unit is then introduced into the open end of syringe barrel 20 so that the threaded body portion 8l is threaded into threads 2 in the syringe barrel flange 24. Next, the retaining clip 60 is positioned over the flange 22 to hold the cartridge assembly < When the syringe is to be used, the plunger rod 50 is threadedly affixed to the plunger 0 and the syringe unit is then activated by pushing forwardly on the plunger rod to force the cartridge assembly toward the needle 102 to the position shown in Pig. 2 wherein- the needle 102 has pierced the stopper 90 and the peripheral bead 78 on sleeve 76 fits into annular recess 10β to lock the cartridge assembly in place. At this stage, the cannula sheath 120 is removed and the injection cannula 87 is directed into the patient. Next, the plunger rod is pulled slightly rearward -ly to aspirate after which the plunger rod is pushed forwardly whereby the medicament 110 is injected. Alternatively, the syringe unit may be stored with the plunger rod threadedly affixed to the plunger in order to avoid delay at the time of use.

As will be noted, the activating of the syringe unit, the insertion of the cannula into the patient and the injection of the medicament are all accomplished by a thrust in the direction of the injection cannula by the person handling the syringe unit. This coupled with the usual aspiration step assures that the party using the syringe will be able to follow standard injection steps and thus obviate any possibility of improper injection.

The medicament 110 may be of the type which over a period of time will give off gases or even expand under high temperature conditions. In order to make certain that the plunger 40 is not forced out of the cylindrical cartridge body 30 when the cartridge assembly is stored prior to assembly in the syringe barrel 20, a retaining member 130 i itte e n e a Fig. 4. The retaining member 130 comprises an outer circular sheath 132 and a generally coextensive inner circular sheath 134 inwardly therefrom to form an annular space 136. The two sheath portions 132 and 13 are connected at one end to close off this space 136. When the retaining member 130 is fitted down over the open end of the cartridge body 3 , the end of the inner sheath 136 will bear against plunger 40 in the manner indicated in Fig. 4. As will be readily apparent, the embodiment of Fig. 4 is the same as that of Fig. 1, except for the addition of the retaining member 130.

Claims

I CLAIM:

1. A syringe adapted to inject substantial amounts of medicament, said syringe comprising a cylindrical syringe barrel having a rear open end and a forward end provided with internal threads, a cylindrical cartridge body slidably carried within said barrel, said cartridge body haying a rear open end and a necked portion at the forward end, a plunger slidably carried within the cartridge body, a stopper mounted in the necked end of the cartridge body to form a closed medicament chamber between said stopper and the plunger, retaining means on the rear end portion of the syringe barrel to retain the cartridge body within the barrel and the plunger within the cartridge body, the improvement comprising: a cannula mounting body member having a threaded section threadedly engaging the internal threads on the forward end of the syringe barrel so as to fixedly position said body member in the forward end of said barrel, a needle support integral with and extending rearwardly from the cannula mounting body member, a hollow needle affixed to the neddle support with its free end spaced from the cartridge stopper, cooperating means on the necked portion of the cartridge and the needle support to provide sterility of the needle and to maintain relative position of the needle with respect to the cartridge stopper, a cannula hub mounting portion integral with and extending forwardly from the body: member, said cannula hub mounting portion comprising an integral forwardly extending outer sleeve within said outer sleeve, a cannula having a hub with an annular peripheral flange thereon, the cannula hub fitting over the inner sleeve with the hub flange engaging the internal threads on the outer sleeve, a passage connecting the needle and the cannula, said inner sleeve forming a portion of the passage connecting the needle and the cannula, and a cannula sheath covering the cannula and snugly engaging the outer surface of the outer sleeve of the cannula hub mounting portion to form a sterile seal so as to maintain sterile integrity of the cannula.

2. The invention as set forth in claim 1 and vherein the cannula hub and the cannula hub mounting member are provided with flat peripheral faces to assist in assembling of the same.

3. The invention as set forth in claim 1 and wherein the medicament chamber is filled with a medicament and the rear end portion of the cartridge body is provided with a retaining member to prevent expulsion of the plunger from the cartridge body upon expansion of the medicament.

4. A syringe adapted to inject substantial amounts of medicament, said syringe comprising a cylindrical syringe barrel having a rear open end and a necked forward end provided with internal threads, a cylindrical cartridge body slidably carried within said barrel, said cartridge body having a rear open end and a necked portion at the forward end, a plunger slidably carried within the cartridge body, a stopper mounted in the necked end of the cartridge body to form a closed medicament chamber between said stopper and the plunger, a cap fitting over and secured to the necked portion of the cartridge body, said cap having a cylindrical sleeve extending forwardly and coaxial with the longitudinal axis of the cartridge body, a cannula mounting body member, a cylindrical needle support extending from the rearward side of the body member and slidably fitting within the cap sleeve, a needle affixed to the outer end of the support with its free end spaced from the stopper, cooperating positioning means on the needle support and cap sleeve to maintain the relative position of the needle and the stopper, a cannula hub mounting portion extending <~ forwardly from the body member, said hub mounting portion having internal threads, a cannula having a hub with an annular peripheral flange thereon secured to said hub mounting portion by engagement of the annular flange with the internal threads in the aforesaid mounting portion, a cannula sheath covering the cannula to maintain same in sterile condition, the cannula mounting body member having a threaded section sized to threadedly engage the internal threads on the necked portion of the barrel, the cartridge body being carried within the barrel with the cannula directed forward and through the necked portion of the barrel with the threads on the cannula mounting body member engaging the internal threads on the necked portion of the barrel to securely mount the cartridge body and cannula in position with respect to the syringe barrel3 a flange on the rear end portion of the syringe barrel, and a retaining clip fitting over the rear end of the. barrel and secured to the flange to retain the cartridge body and plunger within the barrel.

5. The invention as set forth in claim 4 and wherein the rear end portion of the cartridge body is provided with a retaining member to prevent expulsion of the plunger from the cartridge body upon expansion of the medicament.

6. The invention as set forth in claim and wherein a plunger rod is secured to the plunger and fits through the retaining clip.

7. The invention as set forth in claim 5 and wherein the retaining member comprises a sheath fitting over the rear end of the cartridge body and extending forwardly on both sides thereof whereby the sheath edge on the inner side of the cartridge body will abut the plunger.