IL44738A - Method for in vitro determination of thyroid function and diagnostic reagent composition therefor - Google Patents
Method for in vitro determination of thyroid function and diagnostic reagent composition thereforInfo
- Publication number
- IL44738A IL44738A IL44738A IL4473874A IL44738A IL 44738 A IL44738 A IL 44738A IL 44738 A IL44738 A IL 44738A IL 4473874 A IL4473874 A IL 4473874A IL 44738 A IL44738 A IL 44738A
- Authority
- IL
- Israel
- Prior art keywords
- reagent composition
- diagnostic reagent
- vitro determination
- thyroid function
- silicon dioxide
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Claims (4)
1. „ A diagnostic reagent composition for use in the in vitro determination of thyroid function comprising a buffered aqueous suspension containing: finely divided, amorphous silicon dioxide; a thyroid hormone substance tagged with radioactive iodine and a nonionic surfactant.
2. A diagnostic reagent composition as set . forth in claim 1 wherein said thyroid hormone substance is selected from the group consisting of L-thyroxine and L-triiodothyronine.
3. A diagnostic reagent composition as set forth in claim 1 or 2 wherein said noriionic surfactant is selected from the group consisting of polyoxyethylene alcohols, polyoxyethylene sorbitan fatty acid esters, nonylphenoxypoly (ethyleneoxy) ethanols and sorbitan fatty acid esters.
4.. The method for the in vitro determination of thyroid function which comprises the steps of mixing a blood serum sample with a measured amount of a reagent composition as defined in any one of claims 1 to 3> separating the silicon dioxide from the resulting suspension; and meagurlng the radioactivity of the separated silicon dioxide residue or the supernatant liquid.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36066073A | 1973-05-14 | 1973-05-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL44738A0 IL44738A0 (en) | 1974-06-30 |
| IL44738A true IL44738A (en) | 1976-08-31 |
Family
ID=23418929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL44738A IL44738A (en) | 1973-05-14 | 1974-04-30 | Method for in vitro determination of thyroid function and diagnostic reagent composition therefor |
Country Status (10)
| Country | Link |
|---|---|
| JP (1) | JPS5048986A (en) |
| BE (1) | BE814906A (en) |
| CA (1) | CA1028603A (en) |
| CH (1) | CH581320A5 (en) |
| DE (1) | DE2423174A1 (en) |
| FR (1) | FR2229973B3 (en) |
| GB (1) | GB1428317A (en) |
| IL (1) | IL44738A (en) |
| IT (1) | IT1021547B (en) |
| NL (1) | NL7406237A (en) |
-
1974
- 1974-04-29 GB GB1871774A patent/GB1428317A/en not_active Expired
- 1974-04-30 CA CA198,539A patent/CA1028603A/en not_active Expired
- 1974-04-30 IL IL44738A patent/IL44738A/en unknown
- 1974-05-09 NL NL7406237A patent/NL7406237A/xx not_active Application Discontinuation
- 1974-05-13 DE DE2423174A patent/DE2423174A1/en not_active Withdrawn
- 1974-05-13 JP JP49053162A patent/JPS5048986A/ja active Pending
- 1974-05-13 BE BE1005947A patent/BE814906A/en unknown
- 1974-05-14 CH CH659074A patent/CH581320A5/xx not_active IP Right Cessation
- 1974-05-14 IT IT50982/74A patent/IT1021547B/en active
- 1974-05-14 FR FR7416702A patent/FR2229973B3/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL7406237A (en) | 1974-11-18 |
| FR2229973A1 (en) | 1974-12-13 |
| JPS5048986A (en) | 1975-05-01 |
| FR2229973B3 (en) | 1977-03-11 |
| IT1021547B (en) | 1978-02-20 |
| CH581320A5 (en) | 1976-10-29 |
| CA1028603A (en) | 1978-03-28 |
| DE2423174A1 (en) | 1974-12-05 |
| IL44738A0 (en) | 1974-06-30 |
| GB1428317A (en) | 1976-03-17 |
| BE814906A (en) | 1974-11-13 |
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