IL44721A - Pharmaceutical composition containing certain 1,4-or 1,3-disubstituted piperidine derivatives - Google Patents

Pharmaceutical composition containing certain 1,4-or 1,3-disubstituted piperidine derivatives

Info

Publication number
IL44721A
IL44721A IL44721A IL4472174A IL44721A IL 44721 A IL44721 A IL 44721A IL 44721 A IL44721 A IL 44721A IL 4472174 A IL4472174 A IL 4472174A IL 44721 A IL44721 A IL 44721A
Authority
IL
Israel
Prior art keywords
fluorobenzoyl
propyl
antiemetic
piperidine
composition
Prior art date
Application number
IL44721A
Other languages
English (en)
Other versions
IL44721A0 (en
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of IL44721A0 publication Critical patent/IL44721A0/xx
Publication of IL44721A publication Critical patent/IL44721A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
IL44721A 1973-05-03 1974-04-26 Pharmaceutical composition containing certain 1,4-or 1,3-disubstituted piperidine derivatives IL44721A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/356,975 US4101662A (en) 1973-05-03 1973-05-03 Method for inhibiting emesis and compositions therefor

Publications (2)

Publication Number Publication Date
IL44721A0 IL44721A0 (en) 1974-06-30
IL44721A true IL44721A (en) 1977-06-30

Family

ID=23403763

Family Applications (1)

Application Number Title Priority Date Filing Date
IL44721A IL44721A (en) 1973-05-03 1974-04-26 Pharmaceutical composition containing certain 1,4-or 1,3-disubstituted piperidine derivatives

Country Status (7)

Country Link
US (1) US4101662A (ja)
JP (2) JPS6156227B2 (ja)
AU (1) AU471020B2 (ja)
BE (1) BE814396A (ja)
FR (1) FR2227868B1 (ja)
GB (1) GB1429751A (ja)
IL (1) IL44721A (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4246268A (en) * 1979-02-09 1981-01-20 Richardson-Merrell Inc. Neuroleptic-4-(naphthylmethyl)piperidine derivatives
US4284636A (en) * 1979-09-04 1981-08-18 Richardson-Merrell Inc. Cinnamoylpiperidinobutyrophenone antipsychotic agents
US4283404A (en) * 1979-09-04 1981-08-11 Richardson-Merrell Inc. Aroylethenylpiperidinobutyrophenone antipsychotic agents
ZA806501B (en) * 1979-10-27 1981-10-28 Richardson Merrell Inc 4-(4-alkyl-aroyl-1-piperidino)butyrophenone antipsychotic agents
FR2581993B1 (fr) * 1985-05-14 1988-03-18 Synthelabo Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique
US5021428A (en) * 1985-07-02 1991-06-04 Merrell Dow Pharmaceuticals Inc. Novel chemical compounds for the prophylactic treatment of migraine
KR910006138B1 (ko) * 1986-09-30 1991-08-16 에자이 가부시끼가이샤 환상아민 유도체
JP2573195B2 (ja) * 1986-09-30 1997-01-22 エーザイ株式会社 環状アミン誘導体
US4870083A (en) * 1987-11-24 1989-09-26 Merrell Dow Pharmaceuticals Inc. 1,4-Disubstituted-piperidinyl compounds useful as analgesics and muscle relaxants
US5523307A (en) * 1987-11-27 1996-06-04 Eisai Co., Ltd. Cyclic amine and pharmacological composition
DE3854991T2 (de) * 1987-11-27 1996-07-18 Eisai Co Ltd Cyclische Amine und pharmakologische Verbindungen
US5196439A (en) * 1987-11-27 1993-03-23 Eisai Co., Ltd. Piperidine compounds useful to treat cerebrovascular diseases
US5162342A (en) * 1988-01-21 1992-11-10 Merrell Dow Pharmaceuticals Inc. Use of 1,4-disubstituted-piperidinyl compounds for analgesia and muscle relaxation
EP0661266A1 (en) * 1993-12-27 1995-07-05 Toa Eiyo Ltd. Substituted cyclic amine compounds as 5HT2 antagonists
KR20050085673A (ko) * 2002-12-18 2005-08-29 에프엠씨 코포레이션 Ｎ-(치환된 아릴메틸)-4-(이치환된 메틸)피페리딘 및피페라진

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3128278A (en) * 1964-04-07 Substituted l
US3576810A (en) * 1968-06-20 1971-04-27 Robins Co Inc A H 1-substituted-3-(-4)-aroylpiperidines
US3852455A (en) * 1970-11-27 1974-12-03 Richardson Merrell Inc 4-{8 4({60 hydroxybenzyl)piperidino{9 -4-fluorobutyrophenone derivatives as tranquilizers

Also Published As

Publication number Publication date
JPS6156227B2 (ja) 1986-12-01
FR2227868B1 (ja) 1977-09-09
IL44721A0 (en) 1974-06-30
AU471020B2 (en) 1976-04-08
BE814396A (fr) 1974-08-16
JPS59152371A (ja) 1984-08-31
AU6851674A (en) 1975-11-06
GB1429751A (en) 1976-03-24
JPS5018477A (ja) 1975-02-26
FR2227868A1 (ja) 1974-11-29
JPS6131099B2 (ja) 1986-07-17
US4101662A (en) 1978-07-18

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