IL44625A - Diuretic and antihypertensive compositions containing certain pyrazole derivatives - Google Patents
Diuretic and antihypertensive compositions containing certain pyrazole derivativesInfo
- Publication number
- IL44625A IL44625A IL44625A IL4462574A IL44625A IL 44625 A IL44625 A IL 44625A IL 44625 A IL44625 A IL 44625A IL 4462574 A IL4462574 A IL 4462574A IL 44625 A IL44625 A IL 44625A
- Authority
- IL
- Israel
- Prior art keywords
- diuretic
- compositions containing
- pyrazole derivatives
- containing certain
- certain pyrazole
- Prior art date
Links
- 230000003276 anti-hypertensive effect Effects 0.000 title 1
- 239000002934 diuretic Substances 0.000 title 1
- 230000001882 diuretic effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000003217 pyrazoles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
- C07D231/52—Oxygen atom in position 3 and nitrogen atom in position 5, or vice versa
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2319278A DE2319278C2 (de) | 1973-04-17 | 1973-04-17 | Pharmazeutisches Mittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL44625A0 IL44625A0 (en) | 1974-06-30 |
| IL44625A true IL44625A (en) | 1978-07-31 |
Family
ID=5878313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL44625A IL44625A (en) | 1973-04-17 | 1974-04-12 | Diuretic and antihypertensive compositions containing certain pyrazole derivatives |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US4018890A (enEXAMPLES) |
| BE (1) | BE813745A (enEXAMPLES) |
| DE (1) | DE2319278C2 (enEXAMPLES) |
| FR (1) | FR2226169B1 (enEXAMPLES) |
| GB (1) | GB1434171A (enEXAMPLES) |
| IE (1) | IE39211B1 (enEXAMPLES) |
| IL (1) | IL44625A (enEXAMPLES) |
| LU (1) | LU69870A1 (enEXAMPLES) |
| NL (1) | NL178564C (enEXAMPLES) |
| PH (1) | PH10818A (enEXAMPLES) |
| ZA (1) | ZA742383B (enEXAMPLES) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2427272C3 (de) | 1974-06-06 | 1981-10-01 | Bayer Ag, 5090 Leverkusen | 1-(2-(β-Naphthyloxy)-äthyl)-3-methyl -pyrazolon-(5), Verfahren sowie Verwendung als Antithrombotikum |
| CA1229553A (en) * | 1983-05-18 | 1987-11-24 | Edmund Y. Lukevits | Pharmaceutical preparation for the treatment of hypertensive disease and myocardial infarction |
| DE3436383A1 (de) * | 1984-10-04 | 1986-04-10 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von pyrazolonderivaten |
| USRE35801E (en) * | 1985-05-20 | 1998-05-19 | Mitsubishi Chemical Corporation | Prophylactic and therapeutic composition for circulatory disorders and method of treatment |
| DK169672B1 (da) * | 1985-05-20 | 1995-01-09 | Mitsubishi Chem Ind | Farmaceutiske præparater indeholdende pyrazolonderivater som aktiv bestanddel og anvendelsen af pyrazolonderivater til fremstilling af farmaceutiske præparater |
| DE3626908A1 (de) * | 1986-08-08 | 1988-02-11 | Bayer Ag | Parenterale loesung |
| AU2003250483A1 (en) | 2002-08-19 | 2004-03-11 | Pfizer Products Inc. | Combination therapy for hyperproliferative diseases |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| JP5498168B2 (ja) | 2006-12-01 | 2014-05-21 | ブリストル−マイヤーズ スクイブ カンパニー | アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体 |
| BR112015026513A2 (pt) | 2013-04-17 | 2017-07-25 | Pfizer | derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares |
| US9573122B2 (en) * | 2014-08-29 | 2017-02-21 | Chevron U.S.A. Inc. | Small crystal LTL framework type zeolites |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| FI3911648T3 (fi) | 2019-01-18 | 2025-01-10 | Astrazeneca Ab | 6'-[[[(1s,3s)-3-[[5-(difluorometoksi)-2-pyrimidinyyli]amino]syklopentyyli]amino][1(2h),3'-bipyridin]-2-oni pcsk9:n estäjänä ja menetelmät sen käyttöön |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2476987A (en) * | 1949-07-26 | S-acyloxy pyrazqles and method foe | ||
| US3147276A (en) * | 1964-09-01 | Pyrazolones | ||
| US2376380A (en) * | 1945-05-22 | Preparation of amino pyrazolones | ||
| US2476986A (en) * | 1949-07-26 | Elmobe louis martin | ||
| GB559919A (en) * | 1942-09-07 | 1944-03-10 | Lamson Engineering Co | Improvements in and relating to pneumatic tube conveyor systems |
| GB636988A (en) * | 1947-12-24 | 1950-05-10 | Gevaert Photo Producten Naamlo | Improvements in and relating to the production of colour photographic images |
| US2511231A (en) * | 1949-03-26 | 1950-06-13 | Eastman Kodak Co | 1-cyanophenyl-3-acylamino-5-pyrazolone couplers for color photography |
| US2600788A (en) * | 1949-06-07 | 1952-06-17 | Eastman Kodak Co | Halogen-substituted pyrazolone couplers for color photography |
| CA519436A (en) * | 1949-08-22 | 1955-12-13 | Gysin Hans | Carbamic acid esters as well as pest combatting agents and a method of making the same |
| US2672417A (en) * | 1949-12-31 | 1954-03-16 | Gevaert Photo Prod Nv | Production of color photographic images |
| GB779703A (en) * | 1953-07-06 | 1957-07-24 | Hoechst Ag | Pyrazolone compounds and a process for making them |
| US2848446A (en) * | 1954-02-23 | 1958-08-19 | Saul & Co | Azo dyestuffs |
| DE1003215B (de) * | 1954-08-07 | 1957-02-28 | Hoechst Ag | Verfahren zur Herstellung von 1-Benzyl-3-methyl-pyrazolon-(5) |
| US3014916A (en) * | 1959-01-22 | 1961-12-26 | May & Baker Ltd | Pyrazole derivatives |
| GB935538A (en) * | 1959-04-06 | 1963-08-28 | Stop Motion Devices Corp | Stop-motion head for use on knitting machines |
| GB961037A (en) * | 1960-08-23 | 1964-06-17 | Smith & Nephew | Pyrazolones and processes for their preparation |
| NL279140A (enEXAMPLES) * | 1961-05-31 | |||
| US3190888A (en) * | 1963-08-22 | 1965-06-22 | American Home Prod | Aryloxyalkylpyrazole |
| DE1670529C3 (de) * | 1966-07-13 | 1974-01-10 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt | Substituierte s-Triazine |
| GB1190914A (en) * | 1966-09-26 | 1970-05-06 | Agfa Gevaert Nv | 2-Pyrazolin-5-Ones and the use thereof as Colour Couplers |
| FR1558513A (enEXAMPLES) * | 1968-01-04 | 1969-02-28 | ||
| GB1247688A (en) * | 1968-02-26 | 1971-09-29 | Agfa Gevaert | Monomeric and polymeric 2-pyrazoline-5-one colour couplers |
| JPS4818858B1 (enEXAMPLES) * | 1969-04-07 | 1973-06-08 | ||
| FR2068413A1 (en) * | 1969-10-22 | 1971-08-27 | Synthelabo | 1-alkyl-3-alkylamino-5-aryl-pyrazolines hypo-and hypertensives |
| US3615506A (en) * | 1970-02-09 | 1971-10-26 | Eastman Kodak Co | Silver halide emulsions containing 3-cyclicamino-5-pyrazolone color couplers |
| US3694456A (en) * | 1970-05-08 | 1972-09-26 | Takeda Chemical Industries Ltd | 1-disubstituted aminopyrazoles |
| FR2101060B1 (enEXAMPLES) * | 1970-08-14 | 1974-02-01 | Roussel Uclaf | |
| FR2104931B1 (enEXAMPLES) * | 1970-09-08 | 1975-01-10 | Ferlux | |
| JPS548689B1 (enEXAMPLES) * | 1970-12-04 | 1979-04-18 | ||
| JPS5417772B1 (enEXAMPLES) * | 1970-12-04 | 1979-07-03 | ||
| DE2230792A1 (de) * | 1972-06-23 | 1974-01-17 | Bayer Ag | 3-amino-pyrazolone-(5), verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DE2230675A1 (de) * | 1972-06-23 | 1974-01-10 | Bayer Ag | Diuretisches und antihypertensives mittel |
| AR207445A1 (es) * | 1973-04-17 | 1976-10-08 | Bayer Ag | Procedimiento de preparacion de nuevos derivados de pirazolonas-(5)-1-substituidas |
-
1973
- 1973-04-17 DE DE2319278A patent/DE2319278C2/de not_active Expired
-
1974
- 1974-03-29 FR FR7411442A patent/FR2226169B1/fr not_active Expired
- 1974-04-02 PH PH15695A patent/PH10818A/en unknown
- 1974-04-09 US US05/459,408 patent/US4018890A/en not_active Expired - Lifetime
- 1974-04-12 IL IL44625A patent/IL44625A/xx unknown
- 1974-04-16 LU LU69870A patent/LU69870A1/xx unknown
- 1974-04-16 BE BE143221A patent/BE813745A/xx not_active IP Right Cessation
- 1974-04-16 NL NLAANVRAGE7405114,A patent/NL178564C/xx not_active IP Right Cessation
- 1974-04-16 ZA ZA00742383A patent/ZA742383B/xx unknown
- 1974-04-16 GB GB1650974A patent/GB1434171A/en not_active Expired
- 1974-04-17 IE IE797/74A patent/IE39211B1/xx unknown
-
1979
- 1979-12-12 US US06/102,840 patent/US4288446A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NL7405114A (enEXAMPLES) | 1974-10-21 |
| US4018890A (en) | 1977-04-19 |
| FR2226169A1 (enEXAMPLES) | 1974-11-15 |
| USB459408I5 (enEXAMPLES) | 1976-03-23 |
| LU69870A1 (enEXAMPLES) | 1974-11-21 |
| NL178564C (nl) | 1986-04-16 |
| PH10818A (en) | 1977-09-08 |
| IL44625A0 (en) | 1974-06-30 |
| IE39211L (en) | 1974-10-17 |
| US4288446A (en) | 1981-09-08 |
| AU6793474A (en) | 1975-10-16 |
| IE39211B1 (en) | 1978-08-30 |
| FR2226169B1 (enEXAMPLES) | 1978-07-28 |
| NL178564B (nl) | 1985-11-18 |
| DE2319278A1 (de) | 1974-11-07 |
| BE813745A (fr) | 1974-10-16 |
| ZA742383B (en) | 1975-04-30 |
| GB1434171A (en) | 1976-05-05 |
| DE2319278C2 (de) | 1986-02-20 |
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