ZA742383B - Diuretic and antihypertensive drugs and their use - Google Patents

Diuretic and antihypertensive drugs and their use

Info

Publication number
ZA742383B
ZA742383B ZA00742383A ZA742383A ZA742383B ZA 742383 B ZA742383 B ZA 742383B ZA 00742383 A ZA00742383 A ZA 00742383A ZA 742383 A ZA742383 A ZA 742383A ZA 742383 B ZA742383 B ZA 742383B
Authority
ZA
South Africa
Prior art keywords
diuretic
antihypertensive drugs
antihypertensive
drugs
Prior art date
Application number
ZA00742383A
Other languages
English (en)
Inventor
E Wehinger
H Horstmann
E Moeller
K Meng
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA742383B publication Critical patent/ZA742383B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
    • C07D231/52—Oxygen atom in position 3 and nitrogen atom in position 5, or vice versa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA00742383A 1973-04-17 1974-04-16 Diuretic and antihypertensive drugs and their use ZA742383B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2319278A DE2319278C2 (de) 1973-04-17 1973-04-17 Pharmazeutisches Mittel

Publications (1)

Publication Number Publication Date
ZA742383B true ZA742383B (en) 1975-04-30

Family

ID=5878313

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00742383A ZA742383B (en) 1973-04-17 1974-04-16 Diuretic and antihypertensive drugs and their use

Country Status (11)

Country Link
US (2) US4018890A (xx)
BE (1) BE813745A (xx)
DE (1) DE2319278C2 (xx)
FR (1) FR2226169B1 (xx)
GB (1) GB1434171A (xx)
IE (1) IE39211B1 (xx)
IL (1) IL44625A (xx)
LU (1) LU69870A1 (xx)
NL (1) NL178564C (xx)
PH (1) PH10818A (xx)
ZA (1) ZA742383B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2427272C3 (de) 1974-06-06 1981-10-01 Bayer Ag, 5090 Leverkusen 1-(2-(β-Naphthyloxy)-äthyl)-3-methyl -pyrazolon-(5), Verfahren sowie Verwendung als Antithrombotikum
CA1229553A (en) * 1983-05-18 1987-11-24 Edmund Y. Lukevits Pharmaceutical preparation for the treatment of hypertensive disease and myocardial infarction
DE3436383A1 (de) * 1984-10-04 1986-04-10 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von pyrazolonderivaten
USRE35801E (en) * 1985-05-20 1998-05-19 Mitsubishi Chemical Corporation Prophylactic and therapeutic composition for circulatory disorders and method of treatment
DK169672B1 (da) * 1985-05-20 1995-01-09 Mitsubishi Chem Ind Farmaceutiske præparater indeholdende pyrazolonderivater som aktiv bestanddel og anvendelsen af pyrazolonderivater til fremstilling af farmaceutiske præparater
DE3626908A1 (de) * 1986-08-08 1988-02-11 Bayer Ag Parenterale loesung
AU2003250483A1 (en) 2002-08-19 2004-03-11 Pfizer Products Inc. Combination therapy for hyperproliferative diseases
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのｎ−ピペリジン−３−イルベンズアミド誘導体
US9573122B2 (en) * 2014-08-29 2017-02-21 Chevron U.S.A. Inc. Small crystal LTL framework type zeolites
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
JOP20210193A1 (ar) 2019-01-18 2023-01-30 Astrazeneca Ab مثبطات pcsk9 وطرق استخدامها

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2476986A (en) * 1949-07-26 Elmobe louis martin
US2376380A (en) * 1945-05-22 Preparation of amino pyrazolones
US2476987A (en) * 1949-07-26 S-acyloxy pyrazqles and method foe
US3147276A (en) * 1964-09-01 Pyrazolones
GB559919A (en) * 1942-09-07 1944-03-10 Lamson Engineering Co Improvements in and relating to pneumatic tube conveyor systems
GB636988A (en) * 1947-12-24 1950-05-10 Gevaert Photo Producten Naamlo Improvements in and relating to the production of colour photographic images
US2511231A (en) * 1949-03-26 1950-06-13 Eastman Kodak Co 1-cyanophenyl-3-acylamino-5-pyrazolone couplers for color photography
US2600788A (en) * 1949-06-07 1952-06-17 Eastman Kodak Co Halogen-substituted pyrazolone couplers for color photography
ZA10401B (xx) * 1949-08-22
US2672417A (en) * 1949-12-31 1954-03-16 Gevaert Photo Prod Nv Production of color photographic images
GB779703A (en) * 1953-07-06 1957-07-24 Hoechst Ag Pyrazolone compounds and a process for making them
US2848446A (en) * 1954-02-23 1958-08-19 Saul & Co Azo dyestuffs
DE1003215B (de) * 1954-08-07 1957-02-28 Hoechst Ag Verfahren zur Herstellung von 1-Benzyl-3-methyl-pyrazolon-(5)
US3014916A (en) * 1959-01-22 1961-12-26 May & Baker Ltd Pyrazole derivatives
GB935538A (en) * 1959-04-06 1963-08-28 Stop Motion Devices Corp Stop-motion head for use on knitting machines
GB961037A (en) * 1960-08-23 1964-06-17 Smith & Nephew Pyrazolones and processes for their preparation
NL279140A (xx) * 1961-05-31
US3190888A (en) * 1963-08-22 1965-06-22 American Home Prod Aryloxyalkylpyrazole
DE1670529C3 (de) * 1966-07-13 1974-01-10 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Substituierte s-Triazine
GB1190914A (en) * 1966-09-26 1970-05-06 Agfa Gevaert Nv 2-Pyrazolin-5-Ones and the use thereof as Colour Couplers
FR1558513A (xx) * 1968-01-04 1969-02-28
GB1247688A (en) * 1968-02-26 1971-09-29 Agfa Gevaert Monomeric and polymeric 2-pyrazoline-5-one colour couplers
JPS4818858B1 (xx) * 1969-04-07 1973-06-08
FR2068413A1 (en) * 1969-10-22 1971-08-27 Synthelabo 1-alkyl-3-alkylamino-5-aryl-pyrazolines hypo-and hypertensives
US3615506A (en) * 1970-02-09 1971-10-26 Eastman Kodak Co Silver halide emulsions containing 3-cyclicamino-5-pyrazolone color couplers
US3694456A (en) * 1970-05-08 1972-09-26 Takeda Chemical Industries Ltd 1-disubstituted aminopyrazoles
FR2101060B1 (xx) * 1970-08-14 1974-02-01 Roussel Uclaf
FR2104931B1 (xx) * 1970-09-08 1975-01-10 Ferlux
JPS548689B1 (xx) * 1970-12-04 1979-04-18
JPS5417772B1 (xx) * 1970-12-04 1979-07-03
DE2230675A1 (de) * 1972-06-23 1974-01-10 Bayer Ag Diuretisches und antihypertensives mittel
DE2230792A1 (de) * 1972-06-23 1974-01-17 Bayer Ag 3-amino-pyrazolone-(5), verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
AR207445A1 (es) * 1973-04-17 1976-10-08 Bayer Ag Procedimiento de preparacion de nuevos derivados de pirazolonas-(5)-1-substituidas

Also Published As

Publication number Publication date
LU69870A1 (xx) 1974-11-21
DE2319278A1 (de) 1974-11-07
GB1434171A (en) 1976-05-05
IL44625A (en) 1978-07-31
FR2226169B1 (xx) 1978-07-28
IL44625A0 (en) 1974-06-30
NL178564B (nl) 1985-11-18
IE39211L (en) 1974-10-17
US4018890A (en) 1977-04-19
BE813745A (fr) 1974-10-16
NL7405114A (xx) 1974-10-21
FR2226169A1 (xx) 1974-11-15
AU6793474A (en) 1975-10-16
NL178564C (nl) 1986-04-16
USB459408I5 (xx) 1976-03-23
PH10818A (en) 1977-09-08
US4288446A (en) 1981-09-08
IE39211B1 (en) 1978-08-30
DE2319278C2 (de) 1986-02-20

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