IL43915A - A device for extension in the form of prolonged release and a method for extending an active factor - Google Patents
A device for extension in the form of prolonged release and a method for extending an active factorInfo
- Publication number
- IL43915A IL43915A IL4391573A IL4391573A IL43915A IL 43915 A IL43915 A IL 43915A IL 4391573 A IL4391573 A IL 4391573A IL 4391573 A IL4391573 A IL 4391573A IL 43915 A IL43915 A IL 43915A
- Authority
- IL
- Israel
- Prior art keywords
- active agent
- accordance
- sustained release
- environment
- dispensing device
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title claims 27
- 238000013268 sustained release Methods 0.000 title claims 17
- 239000012730 sustained-release form Substances 0.000 title claims 17
- 238000000034 method Methods 0.000 title claims 14
- -1 poly(carboxylic acid) Polymers 0.000 claims 14
- 230000002209 hydrophobic effect Effects 0.000 claims 10
- 241000124008 Mammalia Species 0.000 claims 9
- 125000004432 carbon atom Chemical group C* 0.000 claims 9
- 239000002253 acid Substances 0.000 claims 7
- 238000003780 insertion Methods 0.000 claims 7
- 230000037431 insertion Effects 0.000 claims 7
- 125000001931 aliphatic group Chemical group 0.000 claims 6
- 229940079593 drug Drugs 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 6
- 229920001897 terpolymer Polymers 0.000 claims 5
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 4
- 230000002035 prolonged effect Effects 0.000 claims 4
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 3
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 3
- 125000005907 alkyl ester group Chemical group 0.000 claims 3
- 125000000217 alkyl group Chemical group 0.000 claims 3
- QCHFTSOMWOSFHM-WPRPVWTQSA-N (+)-Pilocarpine Chemical class C1OC(=O)[C@@H](CC)[C@H]1CC1=CN=CN1C QCHFTSOMWOSFHM-WPRPVWTQSA-N 0.000 claims 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N Hydrocortisone Natural products O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims 2
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 2
- 150000001735 carboxylic acids Chemical class 0.000 claims 2
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 claims 2
- 125000000017 cortisol group Chemical group 0.000 claims 2
- 229960000890 hydrocortisone Drugs 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 229920001600 hydrophobic polymer Polymers 0.000 claims 2
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 2
- 239000011976 maleic acid Substances 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 229960003387 progesterone Drugs 0.000 claims 2
- 239000000186 progesterone Substances 0.000 claims 2
- 150000003180 prostaglandins Chemical class 0.000 claims 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 125000003158 alcohol group Chemical group 0.000 claims 1
- 150000008064 anhydrides Chemical class 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 230000002459 sustained effect Effects 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Ophthalmology & Optometry (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31883172A | 1972-12-27 | 1972-12-27 | |
| US31883272A | 1972-12-27 | 1972-12-27 | |
| US00318891A US3811444A (en) | 1972-12-27 | 1972-12-27 | Bioerodible ocular device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL43915A true IL43915A (en) | 1976-08-31 |
Family
ID=27406015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL4391573A IL43915A (en) | 1972-12-27 | 1973-12-26 | A device for extension in the form of prolonged release and a method for extending an active factor |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS613766B2 (instruction) |
| AR (1) | AR206692A1 (instruction) |
| CH (1) | CH603165A5 (instruction) |
| DK (1) | DK144825C (instruction) |
| ES (1) | ES421677A1 (instruction) |
| FR (1) | FR2247259B1 (instruction) |
| GB (1) | GB1417527A (instruction) |
| IE (1) | IE38672B1 (instruction) |
| IL (1) | IL43915A (instruction) |
| IT (1) | IT1055547B (instruction) |
| NL (1) | NL181627C (instruction) |
| SE (1) | SE433908B (instruction) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2013084B (en) * | 1978-01-25 | 1982-07-28 | Alcon Lab Inc | Ophthalmic drug dosage |
| NZ200564A (en) * | 1982-05-10 | 1987-03-06 | Ahi Operations Ltd | Device for slowly releasing chemicals into body cavities of animals |
| GB2150439A (en) * | 1983-07-06 | 1985-07-03 | El Madani Hassan | An intra-uterine contraceptive device |
| US4666704A (en) * | 1985-05-24 | 1987-05-19 | International Minerals & Chemical Corp. | Controlled release delivery system for macromolecules |
| US4875575A (en) * | 1988-01-26 | 1989-10-24 | The Procter & Gamble Company | Pouched laundry wash active dispenser for improved solubility |
| EP2091481A2 (en) * | 2006-12-18 | 2009-08-26 | Alcon Research, Ltd. | Devices and methods for ophthalmic drug delivery |
-
1973
- 1973-01-01 AR AR25170873A patent/AR206692A1/es active
- 1973-12-20 DK DK696173A patent/DK144825C/da not_active IP Right Cessation
- 1973-12-20 GB GB5911173A patent/GB1417527A/en not_active Expired
- 1973-12-20 SE SE7317215A patent/SE433908B/xx unknown
- 1973-12-20 ES ES421677A patent/ES421677A1/es not_active Expired
- 1973-12-21 CH CH1809973A patent/CH603165A5/xx not_active IP Right Cessation
- 1973-12-21 FR FR7345974A patent/FR2247259B1/fr not_active Expired
- 1973-12-21 IE IE232573A patent/IE38672B1/xx unknown
- 1973-12-26 IL IL4391573A patent/IL43915A/en unknown
- 1973-12-27 IT IT7087273A patent/IT1055547B/it active
- 1973-12-27 JP JP481874A patent/JPS613766B2/ja not_active Expired
- 1973-12-27 NL NL7317731A patent/NL181627C/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU6380473A (en) | 1975-06-19 |
| NL181627B (nl) | 1987-05-04 |
| DK144825B (da) | 1982-06-14 |
| DE2363963B2 (de) | 1975-09-25 |
| NL7317731A (instruction) | 1974-07-01 |
| FR2247259B1 (instruction) | 1978-02-03 |
| IE38672L (en) | 1974-06-27 |
| DE2363963A1 (de) | 1974-07-11 |
| AR206692A1 (es) | 1976-08-13 |
| JPS4994818A (instruction) | 1974-09-09 |
| CH603165A5 (instruction) | 1978-08-15 |
| NL181627C (nl) | 1987-10-01 |
| DK144825C (da) | 1982-12-27 |
| SE433908B (sv) | 1984-06-25 |
| GB1417527A (en) | 1975-12-10 |
| FR2247259A1 (instruction) | 1975-05-09 |
| ES421677A1 (es) | 1976-10-01 |
| IE38672B1 (en) | 1978-05-10 |
| IT1055547B (it) | 1982-01-11 |
| JPS613766B2 (instruction) | 1986-02-04 |
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