IL43913A - Preparation of acid D] - 7) a - amino - a - p - hydroxyphenyl (- acetamido [- 3 -) 1, 2, 3 - triazole - 5 - ile (thymethyl - 3 - cephalic - 4 - carboxylitol salt - Google Patents

Preparation of acid D] - 7) a - amino - a - p - hydroxyphenyl (- acetamido [- 3 -) 1, 2, 3 - triazole - 5 - ile (thymethyl - 3 - cephalic - 4 - carboxylitol salt

Info

Publication number
IL43913A
IL43913A IL43913A IL4391373A IL43913A IL 43913 A IL43913 A IL 43913A IL 43913 A IL43913 A IL 43913A IL 4391373 A IL4391373 A IL 4391373A IL 43913 A IL43913 A IL 43913A
Authority
IL
Israel
Prior art keywords
hydroxyphenyl
amino
reaction
formula
acid
Prior art date
Application number
IL43913A
Other languages
English (en)
Hebrew (he)
Other versions
IL43913A0 (en
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IL43913A0 publication Critical patent/IL43913A0/xx
Publication of IL43913A publication Critical patent/IL43913A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL43913A 1972-12-26 1973-12-25 Preparation of acid D] - 7) a - amino - a - p - hydroxyphenyl (- acetamido [- 3 -) 1, 2, 3 - triazole - 5 - ile (thymethyl - 3 - cephalic - 4 - carboxylitol salt IL43913A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31834072A 1972-12-26 1972-12-26

Publications (2)

Publication Number Publication Date
IL43913A0 IL43913A0 (en) 1974-03-14
IL43913A true IL43913A (en) 1977-08-31

Family

ID=23237764

Family Applications (3)

Application Number Title Priority Date Filing Date
IL50774A IL50774A (en) 1972-12-26 1973-12-25 Preparation of D -) - () p - hydroxyphenyl (- glycyl chloride hydrochloride
IL43913A IL43913A (en) 1972-12-26 1973-12-25 Preparation of acid D] - 7) a - amino - a - p - hydroxyphenyl (- acetamido [- 3 -) 1, 2, 3 - triazole - 5 - ile (thymethyl - 3 - cephalic - 4 - carboxylitol salt
IL50774A IL50774A0 (en) 1972-12-26 1976-10-27 The preparation of d-(-)-2-(p-hydroxyphenyl)-glycyl chloride hydrochloride

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL50774A IL50774A (en) 1972-12-26 1973-12-25 Preparation of D -) - () p - hydroxyphenyl (- glycyl chloride hydrochloride

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL50774A IL50774A0 (en) 1972-12-26 1976-10-27 The preparation of d-(-)-2-(p-hydroxyphenyl)-glycyl chloride hydrochloride

Country Status (23)

Country Link
JP (4) JPS5652024B2 (ro)
KR (1) KR780000197B1 (ro)
AR (4) AR203636A1 (ro)
AT (1) AT331397B (ro)
BE (1) BE808924A (ro)
BG (3) BG21233A3 (ro)
CH (1) CH602760A5 (ro)
DD (2) DD110664A5 (ro)
DE (1) DE2364192A1 (ro)
ES (3) ES421707A1 (ro)
FR (2) FR2211216B1 (ro)
GB (3) GB1460914A (ro)
HU (2) HU167560B (ro)
IL (3) IL50774A (ro)
IN (1) IN139259B (ro)
LU (1) LU69080A1 (ro)
NL (1) NL7317715A (ro)
NO (1) NO142710C (ro)
OA (1) OA04655A (ro)
RO (1) RO66051A (ro)
SE (2) SE404692B (ro)
SU (1) SU576948A3 (ro)
ZA (1) ZA739607B (ro)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907667A (en) * 1973-08-22 1975-09-23 Gulf Research Development Co Process for producing a lubricating oil from a residue feed
NZ179268A (en) * 1974-12-13 1978-04-28 Bristol Myers Co Derivative of cephalosporin c, the preparation of certain cephalosporins
NL162387C (nl) * 1977-09-06 1980-05-16 Gist Brocades Nv Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur.
ATA308979A (de) * 1979-04-25 1982-01-15 Biochemie Gmbh Verfahren zur herstellung von (d)-phenylglycylchlorid hydrochloryd-derivaten
EP0018546B1 (en) * 1979-04-25 1983-09-28 BIOCHEMIE Gesellschaft m.b.H. Process for the production of phenylglycyl chloride hydrochlorides
JPS6128429A (ja) * 1983-10-21 1986-02-08 Kazuo Ogata 均質機の分割式均質装置
IT1186778B (it) * 1985-10-15 1987-12-16 Lark Spa Cefatrizina glicerolo solvato cristallino e procedimento per la sua preparazione
JPH01152718U (ro) * 1988-04-13 1989-10-20
CN103772414B (zh) * 2013-12-31 2016-03-09 福建省福抗药业股份有限公司 一种制备丙二醇头孢曲嗪的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1159449B (de) * 1961-03-22 1963-12-19 Gruenenthal Chemie Verfahren zur Herstellung von 6-Acylaminopenicillansaeuren und deren Salzen
IL38099A (en) * 1970-12-17 1976-01-30 Smith Kline French Lab 3-heterocyclyl thiomethylcephalosporins
IE36346B1 (en) * 1971-05-11 1976-10-13 R & L Molecular Research Ltd Antibacterial agents and a process for the preparation thereof
CA1076560A (en) * 1972-06-14 1980-04-29 Smith Kline And French Canada Ltd. 3-heterocyclic thiomethylcephalosporins

Also Published As

Publication number Publication date
JPS5912661B2 (ja) 1984-03-24
FR2267307A1 (ro) 1975-11-07
NO743649L (no) 1974-06-27
JPS4994696A (ro) 1974-09-09
RO66051A (fr) 1979-08-15
AR205560A1 (es) 1976-05-14
IL50774A0 (en) 1976-12-31
AR203636A1 (es) 1975-09-30
IN139259B (ro) 1976-05-29
IL43913A0 (en) 1974-03-14
KR780000197B1 (en) 1978-05-26
JPS5953277B2 (ja) 1984-12-24
AU6384773A (en) 1975-06-26
JPS5191224A (en) 1976-08-10
GB1460915A (en) 1977-01-06
SU576948A3 (ru) 1977-10-15
DD116602A5 (ro) 1975-12-05
AR205561A1 (es) 1976-05-14
ATA1083073A (de) 1975-11-15
SE7512972L (sv) 1975-11-18
NO142710B (no) 1980-06-23
BG21234A3 (bg) 1976-03-20
JPS5191282A (en) 1976-08-10
GB1460914A (en) 1977-01-06
ES444926A1 (es) 1977-11-16
AR203896A1 (es) 1975-10-31
FR2211216B1 (ro) 1977-04-22
FR2267307B1 (ro) 1978-05-19
ES421707A1 (es) 1976-09-16
DD110664A5 (ro) 1975-01-05
CH602760A5 (ro) 1978-07-31
JPS5652024B2 (ro) 1981-12-09
NO142710C (no) 1980-10-01
NL7317715A (ro) 1974-06-28
AT331397B (de) 1976-08-25
JPS5191283A (en) 1976-08-10
LU69080A1 (ro) 1974-08-19
HU167560B (ro) 1975-11-28
BG21601A3 (bg) 1976-07-20
FR2211216A1 (ro) 1974-07-19
GB1460916A (en) 1977-01-06
DE2364192A1 (de) 1974-06-27
ZA739607B (en) 1974-09-25
BE808924A (fr) 1974-06-20
HU169451B (ro) 1976-11-28
ES444927A1 (es) 1977-04-16
BG21233A3 (bg) 1976-03-20
IL50774A (en) 1977-08-31
SE7512971L (sv) 1975-11-18
OA04655A (fr) 1980-12-31
SE404692B (sv) 1978-10-23

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