IL43569A - Cough medicine containing codeine and its production - Google Patents
Cough medicine containing codeine and its productionInfo
- Publication number
- IL43569A IL43569A IL43569A IL4356973A IL43569A IL 43569 A IL43569 A IL 43569A IL 43569 A IL43569 A IL 43569A IL 4356973 A IL4356973 A IL 4356973A IL 43569 A IL43569 A IL 43569A
- Authority
- IL
- Israel
- Prior art keywords
- salt
- codeine
- heptan
- production
- cough medicine
- Prior art date
Links
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 title claims 12
- 206010011224 Cough Diseases 0.000 title claims 9
- 239000003814 drug Substances 0.000 title claims 7
- 238000004519 manufacturing process Methods 0.000 title claims 5
- 229960004126 codeine Drugs 0.000 title claims 3
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 title claims 3
- 150000003839 salts Chemical class 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 7
- LREQLEBVOXIEOM-UHFFFAOYSA-N 6-amino-2-methyl-2-heptanol Chemical compound CC(N)CCCC(C)(C)O LREQLEBVOXIEOM-UHFFFAOYSA-N 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 229960005402 heptaminol Drugs 0.000 claims 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 3
- 239000002253 acid Substances 0.000 claims 2
- 239000000796 flavoring agent Substances 0.000 claims 2
- 235000013355 food flavoring agent Nutrition 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 1
- 238000005422 blasting Methods 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 230000011514 reflex Effects 0.000 claims 1
- 235000020374 simple syrup Nutrition 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 229910021653 sulphate ion Inorganic materials 0.000 claims 1
- 230000008961 swelling Effects 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
Landscapes
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1673972 | 1972-11-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL43569A0 IL43569A0 (en) | 1974-03-14 |
| IL43569A true IL43569A (en) | 1976-01-30 |
Family
ID=4419797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL43569A IL43569A (en) | 1972-11-16 | 1973-11-05 | Cough medicine containing codeine and its production |
Country Status (8)
| Country | Link |
|---|---|
| AT (1) | AT330344B (Direct) |
| BE (1) | BE807454A (Direct) |
| ES (1) | ES419868A1 (Direct) |
| FR (1) | FR2206940B1 (Direct) |
| GB (1) | GB1388099A (Direct) |
| IL (1) | IL43569A (Direct) |
| NL (1) | NL147936B (Direct) |
| SE (1) | SE419162B (Direct) |
-
1973
- 1973-10-17 AT AT880573A patent/AT330344B/de not_active IP Right Cessation
- 1973-10-23 GB GB4936473A patent/GB1388099A/en not_active Expired
- 1973-10-23 ES ES419868A patent/ES419868A1/es not_active Expired
- 1973-11-05 IL IL43569A patent/IL43569A/en unknown
- 1973-11-06 SE SE7315057A patent/SE419162B/xx unknown
- 1973-11-09 NL NL737315355A patent/NL147936B/xx not_active IP Right Cessation
- 1973-11-15 FR FR7340722A patent/FR2206940B1/fr not_active Expired
- 1973-11-16 BE BE137870A patent/BE807454A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2206940A1 (Direct) | 1974-06-14 |
| ES419868A1 (es) | 1976-08-01 |
| ATA880573A (de) | 1975-09-15 |
| AT330344B (de) | 1976-06-25 |
| BE807454A (fr) | 1974-03-15 |
| NL147936B (nl) | 1975-12-15 |
| DE2349157A1 (de) | 1974-05-30 |
| GB1388099A (en) | 1975-03-19 |
| DE2349157B2 (de) | 1977-04-14 |
| IL43569A0 (en) | 1974-03-14 |
| FR2206940B1 (Direct) | 1977-08-19 |
| SE419162B (sv) | 1981-07-20 |
| NL7315355A (Direct) | 1974-05-20 |
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