IL42710A - History of Norbornan, their manufacture and pharmaceutical preparations containing them - Google Patents
History of Norbornan, their manufacture and pharmaceutical preparations containing themInfo
- Publication number
- IL42710A IL42710A IL42710A IL4271073A IL42710A IL 42710 A IL42710 A IL 42710A IL 42710 A IL42710 A IL 42710A IL 4271073 A IL4271073 A IL 4271073A IL 42710 A IL42710 A IL 42710A
- Authority
- IL
- Israel
- Prior art keywords
- acid addition
- hydrogen atom
- addition salts
- compounds
- represent
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims abstract 4
- 150000002847 norbornane derivatives Chemical class 0.000 title claims abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000000034 method Methods 0.000 claims abstract 14
- 239000002253 acid Substances 0.000 claims 16
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 16
- 150000003839 salts Chemical class 0.000 claims 16
- 150000001875 compounds Chemical class 0.000 claims 13
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 7
- 125000006239 protecting group Chemical group 0.000 claims 7
- 238000003797 solvolysis reaction Methods 0.000 claims 6
- 239000000126 substance Substances 0.000 claims 5
- 125000003342 alkenyl group Chemical group 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 239000007858 starting material Substances 0.000 claims 2
- 101100139845 Caenorhabditis elegans rac-2 gene Proteins 0.000 claims 1
- 239000007868 Raney catalyst Substances 0.000 claims 1
- NPXOKRUENSOPAO-UHFFFAOYSA-N Raney nickel Chemical compound [Al].[Ni] NPXOKRUENSOPAO-UHFFFAOYSA-N 0.000 claims 1
- 229910000564 Raney nickel Inorganic materials 0.000 claims 1
- 230000002152 alkylating effect Effects 0.000 claims 1
- 150000007514 bases Chemical class 0.000 claims 1
- VUFQYRAKSQTZEB-UHFFFAOYSA-N bicyclo[2.2.1]heptan-4-amine Chemical compound C1CC2CCC1(N)C2 VUFQYRAKSQTZEB-UHFFFAOYSA-N 0.000 claims 1
- 239000003054 catalyst Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000005984 hydrogenation reaction Methods 0.000 claims 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 150000003141 primary amines Chemical class 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
- C07C209/70—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton by reduction of unsaturated amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1184472A CH571472A5 (de) | 1972-08-10 | 1972-08-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL42710A0 IL42710A0 (en) | 1973-10-25 |
| IL42710A true IL42710A (en) | 1976-10-31 |
Family
ID=4377449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL42710A IL42710A (en) | 1972-08-10 | 1973-07-10 | History of Norbornan, their manufacture and pharmaceutical preparations containing them |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US3884976A (de) |
| JP (1) | JPS4956960A (de) |
| KR (1) | KR780000174B1 (de) |
| AR (2) | AR208169A1 (de) |
| AT (1) | AT331778B (de) |
| AU (1) | AU469307B2 (de) |
| BE (1) | BE803388A (de) |
| CA (1) | CA1020953A (de) |
| CH (1) | CH571472A5 (de) |
| DD (1) | DD107030A5 (de) |
| DE (1) | DE2340160A1 (de) |
| ES (1) | ES417696A1 (de) |
| FR (1) | FR2195442B1 (de) |
| GB (1) | GB1403131A (de) |
| HU (1) | HU167767B (de) |
| IE (1) | IE37977B1 (de) |
| IL (1) | IL42710A (de) |
| LU (1) | LU68183A1 (de) |
| NL (1) | NL7311096A (de) |
| NO (1) | NO137964C (de) |
| PH (1) | PH10790A (de) |
| SU (1) | SU497764A3 (de) |
| ZA (1) | ZA734651B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3968113A (en) * | 1975-02-07 | 1976-07-06 | Eli Lilly And Company | Conversion of leurosine to vincathicine |
| US5986142A (en) * | 1997-09-23 | 1999-11-16 | Poli Industria Chimica Spa | Process for preparing bicycloheptanamine compounds |
| US6121289A (en) * | 1998-10-09 | 2000-09-19 | Theramax, Inc. | Method for enhanced brain delivery of nicotinic antagonist |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2831027A (en) * | 1955-06-06 | 1958-04-15 | Merck & Co Inc | Isocamphane compounds and processes for preparing the same |
| US2894987A (en) * | 1957-04-04 | 1959-07-14 | Merck & Co Inc | N-allyl-2-aminoisocamphane |
| US3148118A (en) * | 1962-06-05 | 1964-09-08 | Thesing Jan | Analeptically active agents |
| US3290215A (en) * | 1963-10-29 | 1966-12-06 | Du Pont | Use of methanoindanamines as antiviral agents |
| US3546291A (en) * | 1966-08-09 | 1970-12-08 | Smithkline Corp | Bicyclo(3.2.1)octane amines |
-
1972
- 1972-08-10 CH CH1184472A patent/CH571472A5/xx not_active IP Right Cessation
-
1973
- 1973-01-01 AR AR249304A patent/AR208169A1/es active
- 1973-07-10 ZA ZA734651A patent/ZA734651B/xx unknown
- 1973-07-10 IL IL42710A patent/IL42710A/en unknown
- 1973-07-17 AU AU58186/73A patent/AU469307B2/en not_active Expired
- 1973-07-30 US US383953A patent/US3884976A/en not_active Expired - Lifetime
- 1973-08-07 IE IE1340/73A patent/IE37977B1/xx unknown
- 1973-08-08 SU SU1955602A patent/SU497764A3/ru active
- 1973-08-08 LU LU68183A patent/LU68183A1/xx unknown
- 1973-08-08 DE DE19732340160 patent/DE2340160A1/de active Pending
- 1973-08-08 DD DD172769A patent/DD107030A5/xx unknown
- 1973-08-08 JP JP48088565A patent/JPS4956960A/ja active Pending
- 1973-08-09 BE BE134380A patent/BE803388A/xx unknown
- 1973-08-09 GB GB3771273A patent/GB1403131A/en not_active Expired
- 1973-08-09 ES ES417696A patent/ES417696A1/es not_active Expired
- 1973-08-09 HU HUHO1602A patent/HU167767B/hu unknown
- 1973-08-09 CA CA178,451A patent/CA1020953A/en not_active Expired
- 1973-08-09 FR FR7329129A patent/FR2195442B1/fr not_active Expired
- 1973-08-09 AT AT700473A patent/AT331778B/de not_active IP Right Cessation
- 1973-08-09 NO NO3192/73A patent/NO137964C/no unknown
- 1973-08-10 PH PH14900A patent/PH10790A/en unknown
- 1973-08-10 KR KR7301305A patent/KR780000174B1/ko not_active Expired
- 1973-08-10 NL NL7311096A patent/NL7311096A/xx not_active Application Discontinuation
-
1974
- 1974-03-26 AR AR252959A patent/AR211512A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| IE37977B1 (en) | 1977-11-23 |
| PH10790A (en) | 1977-09-06 |
| HU167767B (en) | 1975-12-29 |
| IL42710A0 (en) | 1973-10-25 |
| CA1020953A (en) | 1977-11-15 |
| NO137964B (no) | 1978-02-20 |
| ATA700473A (de) | 1975-12-15 |
| DD107030A5 (de) | 1974-07-12 |
| US3884976A (en) | 1975-05-20 |
| AU5818673A (en) | 1975-01-23 |
| AR208169A1 (es) | 1976-12-09 |
| IE37977L (en) | 1974-02-10 |
| KR780000174B1 (en) | 1978-05-13 |
| GB1403131A (en) | 1975-08-13 |
| ZA734651B (en) | 1974-06-26 |
| AR211512A1 (es) | 1978-01-30 |
| FR2195442A1 (de) | 1974-03-08 |
| AU469307B2 (en) | 1976-02-12 |
| SU497764A3 (ru) | 1975-12-30 |
| NO137964C (no) | 1978-05-31 |
| ES417696A1 (es) | 1976-02-01 |
| AT331778B (de) | 1976-08-25 |
| NL7311096A (de) | 1974-02-12 |
| FR2195442B1 (de) | 1976-08-13 |
| CH571472A5 (de) | 1976-01-15 |
| BE803388A (fr) | 1974-02-11 |
| LU68183A1 (de) | 1975-05-21 |
| JPS4956960A (de) | 1974-06-03 |
| DE2340160A1 (de) | 1974-02-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW450965B (en) | Process for mono-and 1,7-bis-N-β-hydroxyalkylation of cyclene; N-β-hydroxyalkyl-1,4,7,10-tetraazacyclododecane-lithium-salt complexes and the use of the complexes for the production of gadobutrol and analogs | |
| GB1509527A (en) | 1-(aryl-or heteroaryl)oxy-3-(substituted-amino)propan-2-ol derivatives processes for their manufacture and pharmaceutical compositions containing them | |
| IE861686L (en) | Alpha cyano -3-phenoxy-4-fluorobenzyl permethrate | |
| US3345379A (en) | 7-imidomethyl-6-demethyl-6-deoxytetracyclines | |
| US3635986A (en) | 2-substituted amino-hexahydrobenzo(a)quinolizines | |
| IL42710A (en) | History of Norbornan, their manufacture and pharmaceutical preparations containing them | |
| GB1474316A (en) | O-aminoalkyl oximes | |
| US3655737A (en) | 1-(3-hydroxy-4-methyl-phenyl)-propylamine (-2) and the salts thereof | |
| US3156688A (en) | Nu-alkyl and nu-aralkyl benzoxacycloalkanemethylamines | |
| IL73372A (en) | (5-phenyl-1,3-dioxan-4-yl)alkenoic or alkanoic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| US3860581A (en) | Preparation of 1,4-benzodiazepines | |
| ES427972A1 (es) | Procedimiento de preparacion de n-arilsulfonil n'- (aza-3 bicicloalquil) ureas. | |
| IL42590A (en) | 3-alkyl-4-sulphamoyl-aniline derivatives and processes for the preparation thereof | |
| DE2114884A1 (de) | Basisch substituierte Derivate des 1(2H)-Phthalazinons | |
| US2523275A (en) | Substituted glycinamides | |
| US2905590A (en) | Thioxanthene derivative | |
| PL120349B1 (en) | Process for preparing novel substituted aminoalkylguanidinesinov | |
| GB1380145A (en) | Acetamidine derivatives process for preparing the same and pharma ceutical uses thereof | |
| US3480674A (en) | N-secondary-alkyl tertiary polyamine compounds | |
| US2735848A (en) | Amese salts of penicillin g | |
| US2741619A (en) | Alkyl 1-alkyl-4-cyclohexylpiperidine-4-carboxylates and their synthesis | |
| KR890006656A (ko) | 약물동력학적으로 개선된 세팔로스포린 유도체, 그의 제조방법 그를 함유하는 약제학적 조성물 및 합성 중간체 | |
| US2683737A (en) | Aromatic hydrocarbon esters of basically substituted aralkylcarbamates and salts thereof | |
| US3278542A (en) | ||
| US3845104A (en) | N-substituted n,n-bis(2-fluoro-2,2-dinitroethyl)amines |