IL42499A - Preparation of n(diethylaminoethyl)2-methoxy 4-amino-5-chlorobenzamide - Google Patents
Preparation of n(diethylaminoethyl)2-methoxy 4-amino-5-chlorobenzamideInfo
- Publication number
- IL42499A IL42499A IL42499A IL4249973A IL42499A IL 42499 A IL42499 A IL 42499A IL 42499 A IL42499 A IL 42499A IL 4249973 A IL4249973 A IL 4249973A IL 42499 A IL42499 A IL 42499A
- Authority
- IL
- Israel
- Prior art keywords
- vith
- chlorobenzamide
- diethylaminoethyl
- methoxy
- amino
- Prior art date
Links
- TTWJBBZEZQICBI-UHFFFAOYSA-N metoclopramide Chemical compound CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC TTWJBBZEZQICBI-UHFFFAOYSA-N 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 150000002148 esters Chemical class 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 150000007524 organic acids Chemical class 0.000 claims 1
- 235000005985 organic acids Nutrition 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (1)
1. C L A I M S A novel method of corresponding to the its salts of addition pharmaceutically acceptable mineral organic acids f its quaternary characterised in that an ester of acid having the in vhich R is a lover alkyl group vith 1 to carbon is reacted vith ethanol and that the resulting is treated vith thiouyl chloride to give vhich reacts vith diethylaaine to give A method according to 1 vherein the ester used is Compounds of the formula wherein X is hydroxy group when Y is and X is chlorine atom when Y is an insufficientOCRQuality
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7222288A FR2277815A1 (en) | 1972-06-20 | 1972-06-20 | NEW PROCESS FOR THE PREPARATION OF N (DIETHYLAMINOETHYL) 2-METHOXY 4-AMINO 5-CHLOROBENZAMIDE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL42499A0 IL42499A0 (en) | 1973-08-29 |
| IL42499A true IL42499A (en) | 1976-11-30 |
Family
ID=9100526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL42499A IL42499A (en) | 1972-06-20 | 1973-06-14 | Preparation of n(diethylaminoethyl)2-methoxy 4-amino-5-chlorobenzamide |
Country Status (26)
| Country | Link |
|---|---|
| JP (3) | JPS5522468B2 (en) |
| KR (1) | KR780000231B1 (en) |
| AT (1) | AT350044B (en) |
| AU (1) | AU468921B2 (en) |
| BE (1) | BE801038A (en) |
| BG (3) | BG22074A3 (en) |
| CA (1) | CA1001170A (en) |
| CH (1) | CH568277A5 (en) |
| CS (1) | CS167389B2 (en) |
| DD (1) | DD107441A5 (en) |
| DE (1) | DE2330373A1 (en) |
| DK (1) | DK131030B (en) |
| ES (1) | ES415952A1 (en) |
| FI (1) | FI56677C (en) |
| FR (1) | FR2277815A1 (en) |
| GB (1) | GB1395131A (en) |
| HU (1) | HU166936B (en) |
| IE (1) | IE37800B1 (en) |
| IL (1) | IL42499A (en) |
| LU (1) | LU67805A1 (en) |
| MC (1) | MC1007A1 (en) |
| NO (1) | NO135092C (en) |
| RO (1) | RO64465A (en) |
| SE (5) | SE402452B (en) |
| YU (1) | YU36691B (en) |
| ZA (1) | ZA734127B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5881689U (en) * | 1981-11-25 | 1983-06-02 | 富士電機冷機株式会社 | Cup type vending machine |
| US4808624A (en) * | 1984-06-28 | 1989-02-28 | Bristol-Myers Company | Pharmacologically active substituted benzamides |
| JPH02148390A (en) * | 1988-11-30 | 1990-06-07 | Fuji Electric Co Ltd | hot item vending machine |
| US10539725B2 (en) | 2016-11-30 | 2020-01-21 | Samsung Electronics Co., Ltd. | Optical filter and camera module and electronic device |
| CN113698321B (en) * | 2021-09-30 | 2023-04-18 | 内蒙古康普药业有限公司 | New metoclopramide diamine impurity and application |
-
1972
- 1972-06-20 FR FR7222288A patent/FR2277815A1/en active Granted
-
1973
- 1973-06-13 GB GB2820373A patent/GB1395131A/en not_active Expired
- 1973-06-14 IL IL42499A patent/IL42499A/en unknown
- 1973-06-14 YU YU1607/73A patent/YU36691B/en unknown
- 1973-06-14 DE DE2330373A patent/DE2330373A1/en active Pending
- 1973-06-15 ES ES415952A patent/ES415952A1/en not_active Expired
- 1973-06-15 NO NO2498/73A patent/NO135092C/no unknown
- 1973-06-15 AU AU56994/73A patent/AU468921B2/en not_active Expired
- 1973-06-15 IE IE986/73A patent/IE37800B1/en unknown
- 1973-06-16 BG BG25556A patent/BG22074A3/xx unknown
- 1973-06-16 BG BG23895A patent/BG22073A3/xx unknown
- 1973-06-16 BG BG025555A patent/BG20570A3/en unknown
- 1973-06-18 DD DD171627A patent/DD107441A5/xx unknown
- 1973-06-18 BE BE1005166A patent/BE801038A/en not_active IP Right Cessation
- 1973-06-18 SE SE7308532A patent/SE402452B/en unknown
- 1973-06-18 LU LU67805A patent/LU67805A1/xx unknown
- 1973-06-18 AT AT531673A patent/AT350044B/en not_active IP Right Cessation
- 1973-06-18 FI FI1953/73A patent/FI56677C/en active
- 1973-06-19 JP JP6967773A patent/JPS5522468B2/ja not_active Expired
- 1973-06-19 CA CA174,384A patent/CA1001170A/en not_active Expired
- 1973-06-19 ZA ZA734127A patent/ZA734127B/en unknown
- 1973-06-19 CS CS4410A patent/CS167389B2/cs unknown
- 1973-06-19 DK DK337673AA patent/DK131030B/en not_active IP Right Cessation
- 1973-06-19 HU HUSO1088A patent/HU166936B/hu unknown
- 1973-06-20 CH CH898873A patent/CH568277A5/xx not_active IP Right Cessation
- 1973-06-20 RO RO7375188A patent/RO64465A/en unknown
- 1973-06-20 KR KR7300971A patent/KR780000231B1/en not_active Expired
- 1973-09-20 JP JP10686073A patent/JPS553340B2/ja not_active Expired
- 1973-09-20 JP JP10686173A patent/JPS553341B2/ja not_active Expired
-
1974
- 1974-06-08 MC MC1048A patent/MC1007A1/en unknown
-
1976
- 1976-02-27 SE SE7602736A patent/SE421070B/en not_active IP Right Cessation
- 1976-02-27 SE SE7602735A patent/SE421069B/en not_active IP Right Cessation
- 1976-06-28 SE SE7607357A patent/SE7607357L/en unknown
- 1976-06-28 SE SE7607356A patent/SE7607356L/en unknown
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