IE37800L - Benzamide derivatives - Google Patents

Benzamide derivatives

Info

Publication number
IE37800L
IE37800L IE730986A IE98673A IE37800L IE 37800 L IE37800 L IE 37800L IE 730986 A IE730986 A IE 730986A IE 98673 A IE98673 A IE 98673A IE 37800 L IE37800 L IE 37800L
Authority
IE
Ireland
Prior art keywords
methoxy
chlorobenzamide
reacting
amino
acetamido
Prior art date
Application number
IE730986A
Other versions
IE37800B1 (en
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ile De France filed Critical Ile De France
Publication of IE37800L publication Critical patent/IE37800L/en
Publication of IE37800B1 publication Critical patent/IE37800B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1395131 N - [2 - (N,N - diethylamino)ethyl]- 2 - methoxy - 4 - amino - 5 - chlorobenzamide SOC D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE 13 June 1973 [20 June 1972] 28203/73 Heading C2C N - [2 - (N<SP>1</SP>,N<SP>1</SP> - diethylamino)ethyl] - 2- methoxy - 4 - amino - 5 - chlorobenzamide is prepared by reacting a C 1-3 alkyl 2-methoxy-4- acetamido-5-chlorobenzoate with ethanolamine, reacting the resulting novel N-(2-hydroxyethyl)- 2 - methoxy - 4 - acetamido - 5 - chlorobenzamide with thionyl chloride, followed by alkaline hydrolysis, and reacting the resulting novel N - (2 - chloroethyl) - 2 - methoxy - 4 - amino - 5- chlorobenzamide with diethylamine; and may subsequently be converted to its pharmaceutically acceptable mineral or organic acid addition salts or quaternary ammonium salts. [GB1395131A]
IE986/73A 1972-06-20 1973-06-15 Benzamide derivatives IE37800B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7222288A FR2277815A1 (en) 1972-06-20 1972-06-20 NEW PROCESS FOR THE PREPARATION OF N (DIETHYLAMINOETHYL) 2-METHOXY 4-AMINO 5-CHLOROBENZAMIDE

Publications (2)

Publication Number Publication Date
IE37800L true IE37800L (en) 1973-12-20
IE37800B1 IE37800B1 (en) 1977-10-12

Family

ID=9100526

Family Applications (1)

Application Number Title Priority Date Filing Date
IE986/73A IE37800B1 (en) 1972-06-20 1973-06-15 Benzamide derivatives

Country Status (26)

Country Link
JP (3) JPS5522468B2 (en)
KR (1) KR780000231B1 (en)
AT (1) AT350044B (en)
AU (1) AU468921B2 (en)
BE (1) BE801038A (en)
BG (3) BG22074A3 (en)
CA (1) CA1001170A (en)
CH (1) CH568277A5 (en)
CS (1) CS167389B2 (en)
DD (1) DD107441A5 (en)
DE (1) DE2330373A1 (en)
DK (1) DK131030B (en)
ES (1) ES415952A1 (en)
FI (1) FI56677C (en)
FR (1) FR2277815A1 (en)
GB (1) GB1395131A (en)
HU (1) HU166936B (en)
IE (1) IE37800B1 (en)
IL (1) IL42499A (en)
LU (1) LU67805A1 (en)
MC (1) MC1007A1 (en)
NO (1) NO135092C (en)
RO (1) RO64465A (en)
SE (5) SE402452B (en)
YU (1) YU36691B (en)
ZA (1) ZA734127B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5881689U (en) * 1981-11-25 1983-06-02 富士電機冷機株式会社 Cup type vending machine
JPS59155682U (en) * 1983-04-05 1984-10-19 東芝機器株式会社 beverage vending machine
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides
JPH02148390A (en) * 1988-11-30 1990-06-07 Fuji Electric Co Ltd Automatic vending machine for hot commodity
US10539725B2 (en) 2016-11-30 2020-01-21 Samsung Electronics Co., Ltd. Optical filter and camera module and electronic device
CN113698321B (en) * 2021-09-30 2023-04-18 内蒙古康普药业有限公司 New metoclopramide diamine impurity and application

Also Published As

Publication number Publication date
DK131030B (en) 1975-05-20
YU36691B (en) 1984-08-31
DD107441A5 (en) 1974-08-05
AT350044B (en) 1979-05-10
BG20570A3 (en) 1975-12-05
IL42499A (en) 1976-11-30
FI56677C (en) 1980-03-10
DE2330373A1 (en) 1974-01-17
SE7602736L (en) 1976-02-27
DK131030C (en) 1975-10-20
JPS5522468B2 (en) 1980-06-17
JPS553340B2 (en) 1980-01-24
IL42499A0 (en) 1973-08-29
ES415952A1 (en) 1976-02-01
FI56677B (en) 1979-11-30
IE37800B1 (en) 1977-10-12
CA1001170A (en) 1976-12-07
MC1007A1 (en) 1974-10-18
SE7602735L (en) 1976-02-27
NO135092B (en) 1976-11-01
JPS4985039A (en) 1974-08-15
GB1395131A (en) 1975-05-21
BE801038A (en) 1973-12-18
SE421070B (en) 1981-11-23
KR780000231B1 (en) 1978-07-01
RO64465A (en) 1979-05-15
LU67805A1 (en) 1974-07-10
FR2277815B1 (en) 1978-10-20
SE421069B (en) 1981-11-23
JPS5070334A (en) 1975-06-11
BG22073A3 (en) 1976-11-25
HU166936B (en) 1975-06-28
AU5699473A (en) 1974-12-19
AU468921B2 (en) 1976-01-29
BG22074A3 (en) 1976-11-25
FR2277815A1 (en) 1976-02-06
YU160773A (en) 1982-06-18
CH568277A5 (en) 1975-10-31
JPS5070333A (en) 1975-06-11
ATA531673A (en) 1978-10-15
CS167389B2 (en) 1976-04-29
SE7607357L (en) 1976-06-28
ZA734127B (en) 1974-05-29
NO135092C (en) 1977-02-09
JPS553341B2 (en) 1980-01-24
SE7607356L (en) 1976-06-28
SE402452B (en) 1978-07-03

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