IL41343A - Pharmaceutical compositions containing n-(benzoylamino-halobenzyl),n-alkyl-glycine amides - Google Patents
Pharmaceutical compositions containing n-(benzoylamino-halobenzyl),n-alkyl-glycine amidesInfo
- Publication number
- IL41343A IL41343A IL41343A IL4134373A IL41343A IL 41343 A IL41343 A IL 41343A IL 41343 A IL41343 A IL 41343A IL 4134373 A IL4134373 A IL 4134373A IL 41343 A IL41343 A IL 41343A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical
- benzoylamino
- compound
- pharmaceutical compositions
- formula
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract 15
- 239000004471 Glycine Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 10
- 239000002253 acid Substances 0.000 claims abstract 6
- -1 isopropylamino group Chemical group 0.000 claims abstract 6
- 150000003839 salts Chemical class 0.000 claims abstract 6
- 239000004480 active ingredient Substances 0.000 claims abstract 3
- 239000003937 drug carrier Substances 0.000 claims abstract 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 claims abstract 2
- 125000000217 alkyl group Chemical group 0.000 claims abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract 2
- 229910052801 chlorine Inorganic materials 0.000 claims abstract 2
- 239000000460 chlorine Substances 0.000 claims abstract 2
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 claims abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 10
- 229940127557 pharmaceutical product Drugs 0.000 claims 10
- 208000004756 Respiratory Insufficiency Diseases 0.000 claims 6
- 201000004193 respiratory failure Diseases 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 230000003115 biocidal effect Effects 0.000 claims 2
- 230000001419 dependent effect Effects 0.000 claims 2
- LKCKUYRPMPUHTD-UHFFFAOYSA-N 2-amino-n-propan-2-ylacetamide Chemical compound CC(C)NC(=O)CN LKCKUYRPMPUHTD-UHFFFAOYSA-N 0.000 claims 1
- 208000027775 Bronchopulmonary disease Diseases 0.000 claims 1
- OMFXVFTZEKFJBZ-UHFFFAOYSA-N Corticosterone Natural products O=C1CCC2(C)C3C(O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 OMFXVFTZEKFJBZ-UHFFFAOYSA-N 0.000 claims 1
- WLMVUCVOAJYFKF-UHFFFAOYSA-N N-[5-chloro-2-[[methyl-[2-oxo-2-(propan-2-ylamino)ethyl]amino]methyl]phenyl]benzamide Chemical compound C(C)(C)NC(CN(C)CC1=C(C=C(C=C1)Cl)NC(C1=CC=CC=C1)=O)=O WLMVUCVOAJYFKF-UHFFFAOYSA-N 0.000 claims 1
- 239000003470 adrenal cortex hormone Substances 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 229940124630 bronchodilator Drugs 0.000 claims 1
- 229940097217 cardiac glycoside Drugs 0.000 claims 1
- 239000002368 cardiac glycoside Substances 0.000 claims 1
- OMFXVFTZEKFJBZ-HJTSIMOOSA-N corticosterone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@H](CC4)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OMFXVFTZEKFJBZ-HJTSIMOOSA-N 0.000 claims 1
- RKHQGWMMUURILY-UHRZLXHJSA-N cortivazol Chemical compound C([C@H]1[C@@H]2C[C@H]([C@]([C@@]2(C)C[C@H](O)[C@@H]1[C@@]1(C)C2)(O)C(=O)COC(C)=O)C)=C(C)C1=CC1=C2C=NN1C1=CC=CC=C1 RKHQGWMMUURILY-UHRZLXHJSA-N 0.000 claims 1
- LPMXVESGRSUGHW-HBYQJFLCSA-N ouabain Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1C[C@@]2(O)CC[C@H]3[C@@]4(O)CC[C@H](C=5COC(=O)C=5)[C@@]4(C)C[C@@H](O)[C@@H]3[C@@]2(CO)[C@H](O)C1 LPMXVESGRSUGHW-HBYQJFLCSA-N 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- 230000000241 respiratory effect Effects 0.000 claims 1
- 230000028327 secretion Effects 0.000 claims 1
- 229930002534 steroid glycoside Natural products 0.000 claims 1
- 238000009423 ventilation Methods 0.000 claims 1
- UCDKONUHZNTQPY-UHFFFAOYSA-N bromhexine hydrochloride Chemical compound Cl.C1CCCCC1N(C)CC1=CC(Br)=CC(Br)=C1N UCDKONUHZNTQPY-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19722203028 DE2203028A1 (de) | 1972-01-22 | 1972-01-22 | Neues atemtherapeutikum |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL41343A0 IL41343A0 (en) | 1973-03-30 |
| IL41343A true IL41343A (en) | 1976-09-30 |
Family
ID=5833732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL41343A IL41343A (en) | 1972-01-22 | 1973-01-19 | Pharmaceutical compositions containing n-(benzoylamino-halobenzyl),n-alkyl-glycine amides |
Country Status (8)
| Country | Link |
|---|---|
| AU (1) | AU472192B2 (enExample) |
| BE (1) | BE794371A (enExample) |
| DE (1) | DE2203028A1 (enExample) |
| FR (1) | FR2169129B1 (enExample) |
| GB (1) | GB1421655A (enExample) |
| IE (1) | IE37086B1 (enExample) |
| IL (1) | IL41343A (enExample) |
| ZA (1) | ZA73263B (enExample) |
-
0
- BE BE794371D patent/BE794371A/xx unknown
-
1972
- 1972-01-22 DE DE19722203028 patent/DE2203028A1/de active Pending
-
1973
- 1973-01-05 IE IE21/73A patent/IE37086B1/xx unknown
- 1973-01-05 GB GB77573A patent/GB1421655A/en not_active Expired
- 1973-01-12 AU AU51056/73A patent/AU472192B2/en not_active Expired
- 1973-01-12 ZA ZA730263A patent/ZA73263B/xx unknown
- 1973-01-19 IL IL41343A patent/IL41343A/en unknown
- 1973-01-22 FR FR7302160A patent/FR2169129B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2203028A1 (de) | 1973-08-02 |
| AU472192B2 (en) | 1976-05-20 |
| IL41343A0 (en) | 1973-03-30 |
| BE794371A (fr) | 1973-07-23 |
| ZA73263B (en) | 1973-11-28 |
| FR2169129A1 (enExample) | 1973-09-07 |
| GB1421655A (en) | 1976-01-21 |
| IE37086B1 (en) | 1977-04-27 |
| IE37086L (en) | 1973-07-22 |
| FR2169129B1 (enExample) | 1976-10-22 |
| AU5105673A (en) | 1974-07-18 |
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