IL41227A - Substituted 1-chromonyloxy-2-hydroxy-3-phenoxypropanes,their preparation and pharmaceutical compositions containing them - Google Patents

Substituted 1-chromonyloxy-2-hydroxy-3-phenoxypropanes,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL41227A
IL41227A IL41227A IL4122773A IL41227A IL 41227 A IL41227 A IL 41227A IL 41227 A IL41227 A IL 41227A IL 4122773 A IL4122773 A IL 4122773A IL 41227 A IL41227 A IL 41227A
Authority
IL
Israel
Prior art keywords
formula
compound
hydroxy
phenoxy
cyano
Prior art date
Application number
IL41227A
Other languages
English (en)
Other versions
IL41227A0 (en
Original Assignee
Miles Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Lab filed Critical Miles Lab
Publication of IL41227A0 publication Critical patent/IL41227A0/xx
Publication of IL41227A publication Critical patent/IL41227A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL41227A 1972-01-14 1973-01-03 Substituted 1-chromonyloxy-2-hydroxy-3-phenoxypropanes,their preparation and pharmaceutical compositions containing them IL41227A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB191272A GB1405253A (en) 1972-01-14 1972-01-14 1- 2-substituted-chromonyloxy-w-hydroxy-3-phenoxy-propanes

Publications (2)

Publication Number Publication Date
IL41227A0 IL41227A0 (en) 1973-03-30
IL41227A true IL41227A (en) 1976-08-31

Family

ID=9730211

Family Applications (1)

Application Number Title Priority Date Filing Date
IL41227A IL41227A (en) 1972-01-14 1973-01-03 Substituted 1-chromonyloxy-2-hydroxy-3-phenoxypropanes,their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US3899513A (fr)
JP (1) JPS5411310B2 (fr)
AR (1) AR194869A1 (fr)
BE (1) BE793969A (fr)
BR (1) BR7300291D0 (fr)
CA (1) CA1010883A (fr)
CH (1) CH585702A5 (fr)
DE (1) DE2301541A1 (fr)
DK (1) DK135349C (fr)
ES (1) ES410559A1 (fr)
FR (1) FR2181667B1 (fr)
GB (1) GB1405253A (fr)
HU (1) HU164946B (fr)
IL (1) IL41227A (fr)
NL (1) NL7300408A (fr)
NO (1) NO138564C (fr)
SE (1) SE396387B (fr)
SU (1) SU469247A3 (fr)
ZA (1) ZA7358B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567201A (en) * 1981-11-25 1986-01-28 Takeda Chemical Industries, Ltd. Diphenoxypropane derivatives and compositions of antiasthmatic and antiinflammatory agents thereof
US5135940A (en) * 1982-09-23 1992-08-04 Merck Frosst Canada, Inc. Leukotriene antagonists
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
US4820867A (en) * 1983-04-21 1989-04-11 Merck Frosst Canada, Inc. Phenoxypropoxy halophenylacetic acids as leukotriene antagonists
ZA844519B (en) * 1983-06-24 1985-02-27 Hoffmann La Roche Dihydrobenzopyran derivatives
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
US4874777A (en) * 1987-04-10 1989-10-17 Eli Lilly And Company Leukotriene antagonists
US4853398A (en) * 1987-04-13 1989-08-01 Eli Lilly And Company Leukotriene antagonists and use thereas
US5352690A (en) * 1992-07-01 1994-10-04 Eli Lilly And Company 1,2,4-trioxygenated benzene derivatives useful as leukotriene antagonists
KR100783255B1 (ko) 2004-02-13 2007-12-06 워너-램버트 캄파니 엘엘씨 안드로젠 수용체 조절제
US7507860B2 (en) 2004-04-13 2009-03-24 Pfizer Inc. Androgen modulators
BRPI0509980A (pt) * 2004-04-22 2007-10-16 Warner Lambert Co moduladores de androgênio
MXPA06015169A (es) 2004-07-08 2007-08-21 Warner Lambert Co Moduladores de androgenos.
TW200724139A (en) 2005-05-05 2007-07-01 Warner Lambert Co Androgen modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1144905A (en) * 1965-03-25 1969-03-12 Fisons Pharmaceuticals Ltd Substituted bis-(2-carboxy-chromonyl-oxy) derivatives and preparation and pharmaceutical compositions thereof
GB1190193A (en) * 1966-07-05 1970-04-29 Fisons Pharmaceuticals Ltd Bis-(2-Carboxy-Chromonyl-Oxy) Derivatives, their preparation, and Pharmaceutical Compositions thereof
GB1292601A (en) * 1968-10-30 1972-10-11 Fisons Pharmaceuticals Ltd Bis-(2-carboxy-chromone) compounds, their preparation and pharmaceutical compositions containing them
GB1290174A (fr) * 1969-05-20 1972-09-20 Fisons Pharmaceuticals Ltd
US3823165A (en) * 1969-10-28 1974-07-09 Fisons Ltd Pharmaceutically active compounds

Also Published As

Publication number Publication date
GB1405253A (en) 1975-09-10
DK135349C (da) 1977-09-26
SE396387B (sv) 1977-09-19
AR194869A1 (es) 1973-08-24
NL7300408A (fr) 1973-07-17
CA1010883A (en) 1977-05-24
FR2181667B1 (fr) 1976-09-03
US3899513A (en) 1975-08-12
JPS5411310B2 (fr) 1979-05-14
NO138564C (no) 1978-09-27
CH585702A5 (fr) 1977-03-15
SU469247A3 (ru) 1975-04-30
DK135349B (da) 1977-04-12
ZA7358B (en) 1973-10-31
BR7300291D0 (pt) 1973-10-25
BE793969A (fr) 1973-05-02
JPS4878171A (fr) 1973-10-20
HU164946B (fr) 1974-05-28
IL41227A0 (en) 1973-03-30
DE2301541A1 (de) 1973-09-06
NO138564B (no) 1978-06-19
ES410559A1 (es) 1976-05-01
FR2181667A1 (fr) 1973-12-07

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