IL41200A - Substituted 3-amino-prop-1-enes,their preparation and pharmaceutical compositions containing them - Google Patents
Substituted 3-amino-prop-1-enes,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL41200A IL41200A IL41200A IL4120072A IL41200A IL 41200 A IL41200 A IL 41200A IL 41200 A IL41200 A IL 41200A IL 4120072 A IL4120072 A IL 4120072A IL 41200 A IL41200 A IL 41200A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- substituted
- represent
- group
- biphenylyl
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims 5
- 238000000034 method Methods 0.000 claims 28
- -1 biphenylyl Chemical group 0.000 claims 19
- 125000005843 halogen group Chemical group 0.000 claims 15
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 11
- 229910052739 hydrogen Inorganic materials 0.000 claims 9
- 239000001257 hydrogen Substances 0.000 claims 9
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 9
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 7
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 229910052799 carbon Inorganic materials 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 4
- 125000004432 carbon atom Chemical group C* 0.000 claims 3
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 2
- 239000005864 Sulphur Substances 0.000 claims 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 125000003983 fluorenyl group Chemical group C1(=CC=CC=2C3=CC=CC=C3CC12)* 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- DYLIWHYUXAJDOJ-OWOJBTEDSA-N (e)-4-(6-aminopurin-9-yl)but-2-en-1-ol Chemical compound NC1=NC=NC2=C1N=CN2C\C=C\CO DYLIWHYUXAJDOJ-OWOJBTEDSA-N 0.000 claims 1
- OVSKIKFHRZPJSS-UHFFFAOYSA-N 2,4-D Chemical compound OC(=O)COC1=CC=C(Cl)C=C1Cl OVSKIKFHRZPJSS-UHFFFAOYSA-N 0.000 claims 1
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 claims 1
- 125000002252 acyl group Chemical group 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 125000001246 bromo group Chemical group Br* 0.000 claims 1
- 238000002425 crystallisation Methods 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 150000002576 ketones Chemical class 0.000 claims 1
- 150000002825 nitriles Chemical class 0.000 claims 1
- 230000000269 nucleophilic effect Effects 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/782—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
- C07C49/788—Ketones containing a keto group bound to a six-membered aromatic ring polycyclic with keto groups bound to a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1516973A GB1434714A (en) | 1971-12-29 | 1971-12-29 | 3-amino-prop-1-enes methods for their preparation |
| GB4874872 | 1972-10-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL41200A0 IL41200A0 (en) | 1973-02-28 |
| IL41200A true IL41200A (en) | 1976-06-30 |
Family
ID=26266323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL41200A IL41200A (en) | 1971-12-29 | 1972-12-28 | Substituted 3-amino-prop-1-enes,their preparation and pharmaceutical compositions containing them |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3932663A (ja) |
| JP (1) | JPS5750774B2 (ja) |
| AR (3) | AR205875A1 (ja) |
| BE (1) | BE793469A (ja) |
| CA (1) | CA1009255A (ja) |
| CH (5) | CH598191A5 (ja) |
| DE (1) | DE2263817A1 (ja) |
| DK (1) | DK143897C (ja) |
| ES (2) | ES410122A1 (ja) |
| FI (1) | FI58490C (ja) |
| FR (1) | FR2166122B1 (ja) |
| HU (1) | HU166958B (ja) |
| IL (1) | IL41200A (ja) |
| NL (1) | NL7217642A (ja) |
| SE (2) | SE395142B (ja) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4079081A (en) * | 1971-12-29 | 1978-03-14 | Burroughs Wellcome Co. | 1,1-Diaryl-3-amino-prop-1-enes |
| HU169636B (ja) * | 1973-03-28 | 1976-12-28 | ||
| PH14982A (en) * | 1979-06-14 | 1982-03-05 | Beecham Group Ltd | 3-nitro-1-phenyl-1-(n-chlorophenyl)-propan-2-ol |
| EP0322151A3 (en) * | 1987-12-23 | 1989-10-04 | Imperial Chemical Industries Plc | Aromatic compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1206427B (de) * | 1962-11-23 | 1965-12-09 | Giulini Gmbh Geb | Verfahren zur Herstellung von blutdruck-steigernden 2-Alkyl-3, 3-diphenylpropen-(2)-ylaminen |
-
0
- BE BE793469D patent/BE793469A/xx not_active IP Right Cessation
-
1972
- 1972-01-01 AR AR245898A patent/AR205875A1/es active
- 1972-12-13 US US05/314,845 patent/US3932663A/en not_active Expired - Lifetime
- 1972-12-27 NL NL7217642A patent/NL7217642A/xx not_active Application Discontinuation
- 1972-12-28 ES ES410122A patent/ES410122A1/es not_active Expired
- 1972-12-28 DK DK650972A patent/DK143897C/da not_active IP Right Cessation
- 1972-12-28 SE SE7217048A patent/SE395142B/xx unknown
- 1972-12-28 DE DE2263817A patent/DE2263817A1/de not_active Ceased
- 1972-12-28 FI FI3668/72A patent/FI58490C/fi active
- 1972-12-28 FR FR7246606A patent/FR2166122B1/fr not_active Expired
- 1972-12-28 CH CH1896272A patent/CH598191A5/xx not_active IP Right Cessation
- 1972-12-28 JP JP48004159A patent/JPS5750774B2/ja not_active Expired
- 1972-12-28 IL IL41200A patent/IL41200A/en unknown
- 1972-12-29 CA CA160,202A patent/CA1009255A/en not_active Expired
- 1972-12-29 HU HUWE475A patent/HU166958B/hu unknown
-
1973
- 1973-01-01 AR AR250872A patent/AR206205A1/es active
- 1973-09-28 ES ES419165A patent/ES419165A1/es not_active Expired
-
1974
- 1974-01-01 AR AR256434A patent/AR205550A1/es active
-
1976
- 1976-02-16 SE SE7601707A patent/SE410311B/xx unknown
-
1977
- 1977-08-29 CH CH1050677A patent/CH609325A5/xx not_active IP Right Cessation
- 1977-08-29 CH CH1050577A patent/CH599105A5/xx not_active IP Right Cessation
- 1977-08-29 CH CH1050977A patent/CH598192A5/xx not_active IP Right Cessation
- 1977-08-29 CH CH1050877A patent/CH609326A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2166122A1 (ja) | 1973-08-10 |
| DK143897B (da) | 1981-10-26 |
| ES419165A1 (es) | 1977-02-01 |
| DE2263817A1 (de) | 1973-07-05 |
| SE410311B (sv) | 1979-10-08 |
| HU166958B (ja) | 1975-06-28 |
| FI58490C (fi) | 1981-02-10 |
| US3932663A (en) | 1976-01-13 |
| CH599105A5 (ja) | 1978-05-12 |
| AR206205A1 (es) | 1976-07-07 |
| CH598192A5 (ja) | 1978-04-28 |
| CA1009255A (en) | 1977-04-26 |
| JPS4875552A (ja) | 1973-10-11 |
| CH609325A5 (ja) | 1979-02-28 |
| CH598191A5 (ja) | 1978-04-28 |
| SE7601707L (sv) | 1976-02-16 |
| FI58490B (fi) | 1980-10-31 |
| SE395142B (sv) | 1977-08-01 |
| NL7217642A (ja) | 1973-07-03 |
| IL41200A0 (en) | 1973-02-28 |
| DK143897C (da) | 1982-04-13 |
| BE793469A (fr) | 1973-06-28 |
| ES410122A1 (es) | 1976-01-01 |
| FR2166122B1 (ja) | 1977-04-15 |
| JPS5750774B2 (ja) | 1982-10-28 |
| AR205550A1 (es) | 1976-05-14 |
| AR205875A1 (es) | 1976-06-15 |
| CH609326A5 (ja) | 1979-02-28 |
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