IL40220A - Anti-androgenic pharmaceutical compositions containing 2-(substituted methylene)cycloalkanones - Google Patents

Anti-androgenic pharmaceutical compositions containing 2-(substituted methylene)cycloalkanones

Info

Publication number
IL40220A
IL40220A IL40220A IL4022072A IL40220A IL 40220 A IL40220 A IL 40220A IL 40220 A IL40220 A IL 40220A IL 4022072 A IL4022072 A IL 4022072A IL 40220 A IL40220 A IL 40220A
Authority
IL
Israel
Prior art keywords
chr
phenyl
grams
substituted
milliliters
Prior art date
Application number
IL40220A
Other languages
English (en)
Other versions
IL40220A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL40220A0 publication Critical patent/IL40220A0/xx
Publication of IL40220A publication Critical patent/IL40220A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/683—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/54—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
IL40220A 1971-09-20 1972-08-28 Anti-androgenic pharmaceutical compositions containing 2-(substituted methylene)cycloalkanones IL40220A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18212371A 1971-09-20 1971-09-20

Publications (2)

Publication Number Publication Date
IL40220A0 IL40220A0 (en) 1972-10-29
IL40220A true IL40220A (en) 1976-07-30

Family

ID=22667147

Family Applications (1)

Application Number Title Priority Date Filing Date
IL40220A IL40220A (en) 1971-09-20 1972-08-28 Anti-androgenic pharmaceutical compositions containing 2-(substituted methylene)cycloalkanones

Country Status (15)

Country Link
JP (1) JPS4836155A (enrdf_load_stackoverflow)
AU (1) AU463813B2 (enrdf_load_stackoverflow)
BE (1) BE788991A (enrdf_load_stackoverflow)
CA (1) CA986015A (enrdf_load_stackoverflow)
DD (1) DD103811A5 (enrdf_load_stackoverflow)
DE (1) DE2245518A1 (enrdf_load_stackoverflow)
ES (1) ES406846A1 (enrdf_load_stackoverflow)
FR (1) FR2154536B1 (enrdf_load_stackoverflow)
GB (1) GB1394717A (enrdf_load_stackoverflow)
IE (1) IE36663B1 (enrdf_load_stackoverflow)
IL (1) IL40220A (enrdf_load_stackoverflow)
NL (1) NL7212741A (enrdf_load_stackoverflow)
PH (1) PH10556A (enrdf_load_stackoverflow)
PL (1) PL85198B1 (enrdf_load_stackoverflow)
ZA (1) ZA725886B (enrdf_load_stackoverflow)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4857029A (enrdf_load_stackoverflow) * 1971-09-22 1973-08-10
JPS493029A (enrdf_load_stackoverflow) * 1972-04-27 1974-01-11
JPS5074038A (enrdf_load_stackoverflow) * 1973-11-07 1975-06-18
FR2399426A1 (fr) * 1977-08-04 1979-03-02 Unicler A-benzylidene-cycloalcanones et alcools correspondants et leur application en therapeutique
DE2951101A1 (de) * 1979-12-19 1981-06-25 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur herstellung von azidobenzalverbindungen
FR2641277B1 (fr) * 1988-12-29 1994-08-26 Rhone Poulenc Agrochimie Azolylmethylcyclopentane ou cyclopentene benzolidene et utilisation comme fongicide
MA21706A1 (fr) * 1988-12-29 1990-07-01 Rhone Poulenc Agrochimie Benzolidene azolylmethylcycloalcane et utilisation comme fongicide.
FR2649101B1 (fr) * 1989-06-30 1994-10-28 Rhone Poulenc Agrochimie Azolylmethylcyclohexane benzilidene et utilisation comme fongicide
JPH10273467A (ja) * 1997-01-29 1998-10-13 Snow Brand Milk Prod Co Ltd 新規テトラロン又はベンゾピラノン誘導体及びその製造方法
US6162810A (en) * 1997-11-17 2000-12-19 The Regents Of The University Of California Inadone and tetralone compounds for inhibiting cell proliferation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1160689A (fr) * 1953-04-13 1958-07-24 Anton Von Waldheim Chemisch Ph Procédé de préparation de divanillydène-cyclohexanone
FR64M (enrdf_load_stackoverflow) * 1960-07-22 1961-01-09
FR1867M (fr) * 1962-04-12 1963-06-17 Egema Composition nouvelle destinée notamment au traitement de la cholestérolémie.
FR1414456A (fr) * 1964-11-19 1965-10-15 Eastman Kodak Co Procédé de préparation des 2-alcoylbutanones et produits obtenus par la mise en oevre de ce procédé

Also Published As

Publication number Publication date
PL85198B1 (enrdf_load_stackoverflow) 1976-04-30
FR2154536B1 (enrdf_load_stackoverflow) 1976-07-02
FR2154536A1 (enrdf_load_stackoverflow) 1973-05-11
DD103811A5 (enrdf_load_stackoverflow) 1974-02-12
CA986015A (en) 1976-03-23
NL7212741A (enrdf_load_stackoverflow) 1973-03-22
AU4618372A (en) 1974-03-07
DE2245518A1 (de) 1973-04-26
IE36663B1 (en) 1977-01-19
IE36663L (en) 1973-03-20
ZA725886B (en) 1974-04-24
PH10556A (en) 1977-06-08
JPS4836155A (enrdf_load_stackoverflow) 1973-05-28
GB1394717A (en) 1975-05-21
AU463813B2 (en) 1975-08-07
IL40220A0 (en) 1972-10-29
BE788991A (fr) 1973-03-19
ES406846A1 (es) 1976-05-01

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