CA986015A - Arylidene cyclanones and process for their use in inhibiting androgen action - Google Patents
Arylidene cyclanones and process for their use in inhibiting androgen actionInfo
- Publication number
- CA986015A CA986015A CA150,548A CA150548A CA986015A CA 986015 A CA986015 A CA 986015A CA 150548 A CA150548 A CA 150548A CA 986015 A CA986015 A CA 986015A
- Authority
- CA
- Canada
- Prior art keywords
- cyclanones
- arylidene
- androgen action
- inhibiting androgen
- inhibiting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003098 androgen Substances 0.000 title 1
- 125000003968 arylidene group Chemical group [H]C(c)=* 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
- C07C49/683—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
- C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/54—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18212371A | 1971-09-20 | 1971-09-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA986015A true CA986015A (en) | 1976-03-23 |
Family
ID=22667147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA150,548A Expired CA986015A (en) | 1971-09-20 | 1972-08-30 | Arylidene cyclanones and process for their use in inhibiting androgen action |
Country Status (15)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4857029A (enrdf_load_stackoverflow) * | 1971-09-22 | 1973-08-10 | ||
| JPS493029A (enrdf_load_stackoverflow) * | 1972-04-27 | 1974-01-11 | ||
| JPS5074038A (enrdf_load_stackoverflow) * | 1973-11-07 | 1975-06-18 | ||
| FR2399426A1 (fr) * | 1977-08-04 | 1979-03-02 | Unicler | A-benzylidene-cycloalcanones et alcools correspondants et leur application en therapeutique |
| DE2951101A1 (de) * | 1979-12-19 | 1981-06-25 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren zur herstellung von azidobenzalverbindungen |
| FR2641277B1 (fr) * | 1988-12-29 | 1994-08-26 | Rhone Poulenc Agrochimie | Azolylmethylcyclopentane ou cyclopentene benzolidene et utilisation comme fongicide |
| MA21706A1 (fr) * | 1988-12-29 | 1990-07-01 | Rhone Poulenc Agrochimie | Benzolidene azolylmethylcycloalcane et utilisation comme fongicide. |
| FR2649101B1 (fr) * | 1989-06-30 | 1994-10-28 | Rhone Poulenc Agrochimie | Azolylmethylcyclohexane benzilidene et utilisation comme fongicide |
| JPH10273467A (ja) * | 1997-01-29 | 1998-10-13 | Snow Brand Milk Prod Co Ltd | 新規テトラロン又はベンゾピラノン誘導体及びその製造方法 |
| US6162810A (en) * | 1997-11-17 | 2000-12-19 | The Regents Of The University Of California | Inadone and tetralone compounds for inhibiting cell proliferation |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1160689A (fr) * | 1953-04-13 | 1958-07-24 | Anton Von Waldheim Chemisch Ph | Procédé de préparation de divanillydène-cyclohexanone |
| FR64M (enrdf_load_stackoverflow) * | 1960-07-22 | 1961-01-09 | ||
| FR1867M (fr) * | 1962-04-12 | 1963-06-17 | Egema | Composition nouvelle destinée notamment au traitement de la cholestérolémie. |
| FR1414456A (fr) * | 1964-11-19 | 1965-10-15 | Eastman Kodak Co | Procédé de préparation des 2-alcoylbutanones et produits obtenus par la mise en oevre de ce procédé |
-
0
- BE BE788991D patent/BE788991A/xx unknown
-
1972
- 1972-08-28 IL IL40220A patent/IL40220A/en unknown
- 1972-08-28 ZA ZA725886A patent/ZA725886B/xx unknown
- 1972-08-30 CA CA150,548A patent/CA986015A/en not_active Expired
- 1972-08-31 AU AU46183/72A patent/AU463813B2/en not_active Expired
- 1972-09-01 IE IE1189/72A patent/IE36663B1/xx unknown
- 1972-09-07 PH PH13872A patent/PH10556A/en unknown
- 1972-09-15 DE DE2245518A patent/DE2245518A1/de active Pending
- 1972-09-18 PL PL1972157806A patent/PL85198B1/pl unknown
- 1972-09-19 GB GB4337572A patent/GB1394717A/en not_active Expired
- 1972-09-19 ES ES406846A patent/ES406846A1/es not_active Expired
- 1972-09-20 FR FR7233325A patent/FR2154536B1/fr not_active Expired
- 1972-09-20 JP JP47093762A patent/JPS4836155A/ja active Pending
- 1972-09-20 DD DD165766A patent/DD103811A5/xx unknown
- 1972-09-20 NL NL7212741A patent/NL7212741A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL85198B1 (enrdf_load_stackoverflow) | 1976-04-30 |
| FR2154536B1 (enrdf_load_stackoverflow) | 1976-07-02 |
| FR2154536A1 (enrdf_load_stackoverflow) | 1973-05-11 |
| DD103811A5 (enrdf_load_stackoverflow) | 1974-02-12 |
| NL7212741A (enrdf_load_stackoverflow) | 1973-03-22 |
| AU4618372A (en) | 1974-03-07 |
| DE2245518A1 (de) | 1973-04-26 |
| IE36663B1 (en) | 1977-01-19 |
| IE36663L (en) | 1973-03-20 |
| ZA725886B (en) | 1974-04-24 |
| PH10556A (en) | 1977-06-08 |
| JPS4836155A (enrdf_load_stackoverflow) | 1973-05-28 |
| GB1394717A (en) | 1975-05-21 |
| AU463813B2 (en) | 1975-08-07 |
| IL40220A0 (en) | 1972-10-29 |
| BE788991A (fr) | 1973-03-19 |
| IL40220A (en) | 1976-07-30 |
| ES406846A1 (es) | 1976-05-01 |
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