BE788991A - Arylidene cyclanones et methode d'utilisation de celles-ci dansl'inhibition de l'action des androgenes - Google Patents

Arylidene cyclanones et methode d'utilisation de celles-ci dansl'inhibition de l'action des androgenes

Info

Publication number
BE788991A
BE788991A BE788991DA BE788991A BE 788991 A BE788991 A BE 788991A BE 788991D A BE788991D A BE 788991DA BE 788991 A BE788991 A BE 788991A
Authority
BE
Belgium
Prior art keywords
cyclanones
arylidene
androgens
inhibition
action
Prior art date
Application number
Other languages
English (en)
Inventor
W B Scanlon
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Publication of BE788991A publication Critical patent/BE788991A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/683Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/46Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/54Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
BE788991D 1971-09-20 Arylidene cyclanones et methode d'utilisation de celles-ci dansl'inhibition de l'action des androgenes BE788991A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18212371A 1971-09-20 1971-09-20

Publications (1)

Publication Number Publication Date
BE788991A true BE788991A (fr) 1973-03-19

Family

ID=22667147

Family Applications (1)

Application Number Title Priority Date Filing Date
BE788991D BE788991A (fr) 1971-09-20 Arylidene cyclanones et methode d'utilisation de celles-ci dansl'inhibition de l'action des androgenes

Country Status (15)

Country Link
JP (1) JPS4836155A (fr)
AU (1) AU463813B2 (fr)
BE (1) BE788991A (fr)
CA (1) CA986015A (fr)
DD (1) DD103811A5 (fr)
DE (1) DE2245518A1 (fr)
ES (1) ES406846A1 (fr)
FR (1) FR2154536B1 (fr)
GB (1) GB1394717A (fr)
IE (1) IE36663B1 (fr)
IL (1) IL40220A (fr)
NL (1) NL7212741A (fr)
PH (1) PH10556A (fr)
PL (1) PL85198B1 (fr)
ZA (1) ZA725886B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4857029A (fr) * 1971-09-22 1973-08-10
JPS493029A (fr) * 1972-04-27 1974-01-11
JPS5074038A (fr) * 1973-11-07 1975-06-18
FR2399426A1 (fr) * 1977-08-04 1979-03-02 Unicler A-benzylidene-cycloalcanones et alcools correspondants et leur application en therapeutique
DE2951101A1 (de) * 1979-12-19 1981-06-25 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur herstellung von azidobenzalverbindungen
FR2649101B1 (fr) * 1989-06-30 1994-10-28 Rhone Poulenc Agrochimie Azolylmethylcyclohexane benzilidene et utilisation comme fongicide
FR2641277B1 (fr) * 1988-12-29 1994-08-26 Rhone Poulenc Agrochimie Azolylmethylcyclopentane ou cyclopentene benzolidene et utilisation comme fongicide
CA2006309C (fr) * 1988-12-29 2001-12-18 Jean Hutt Azolylmethylcyclopentane benzylidene fongicide
JPH10273467A (ja) * 1997-01-29 1998-10-13 Snow Brand Milk Prod Co Ltd 新規テトラロン又はベンゾピラノン誘導体及びその製造方法
US6162810A (en) * 1997-11-17 2000-12-19 The Regents Of The University Of California Inadone and tetralone compounds for inhibiting cell proliferation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1160689A (fr) * 1953-04-13 1958-07-24 Anton Von Waldheim Chemisch Ph Procédé de préparation de divanillydène-cyclohexanone
FR64M (fr) * 1960-07-22 1961-01-09
FR1867M (fr) * 1962-04-12 1963-06-17 Egema Composition nouvelle destinée notamment au traitement de la cholestérolémie.
FR1414456A (fr) * 1964-11-19 1965-10-15 Eastman Kodak Co Procédé de préparation des 2-alcoylbutanones et produits obtenus par la mise en oevre de ce procédé

Also Published As

Publication number Publication date
PL85198B1 (fr) 1976-04-30
ES406846A1 (es) 1976-05-01
FR2154536B1 (fr) 1976-07-02
NL7212741A (fr) 1973-03-22
DE2245518A1 (de) 1973-04-26
CA986015A (en) 1976-03-23
AU463813B2 (en) 1975-08-07
IL40220A0 (en) 1972-10-29
ZA725886B (en) 1974-04-24
FR2154536A1 (fr) 1973-05-11
AU4618372A (en) 1974-03-07
JPS4836155A (fr) 1973-05-28
GB1394717A (en) 1975-05-21
IL40220A (en) 1976-07-30
DD103811A5 (fr) 1974-02-12
PH10556A (en) 1977-06-08
IE36663L (en) 1973-03-20
IE36663B1 (en) 1977-01-19

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